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General Thoracic and Cardiovascular Surgery

Published in:

01-07-2018 | Case Report

A surgical case of methotrexate-associated lymphomatoid granuloma

Authors: Hajime Watanabe, Ryota Masuda, Tomohiko Matsuzaki, Rurika Hamanaka, Yoichiro Ikoma, Takayuki Nakano, Kana Oiwa, Mitsutomo Kohno, Masayuki Iwazaki

Published in: General Thoracic and Cardiovascular Surgery | Issue 7/2018

Abstract

We reported a surgical case of methotrexate-associated lymphomatoid granuloma. A 69-year-old female had been treated with methotrexate for rheumatoid arthritis for 35 months. The patient underwent partial resection of the right upper pulmonary lobe for lung cancer when she was 67 years old. A nodule was detected in the left lung field on a chest radiograph performed during the postoperative follow-up period. Computed tomography revealed a 28-mm nodule in the lower left pulmonary lobe. A transbronchial biopsy examination did not lead to a diagnosis. The pulmonary nodule subsequently increased in size. We suspected a malignant tumor and performed lower left lobectomy. A pathological examination revealed lymphomatoid granuloma. Finally, the patient was diagnosed with methotrexate-associated lymphomatoid granuloma based on her history of oral methotrexate treatment.

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Title: A surgical case of methotrexate-associated lymphomatoid granuloma
Authors: Hajime Watanabe
Ryota Masuda
Tomohiko Matsuzaki
Rurika Hamanaka
Yoichiro Ikoma
Takayuki Nakano
Kana Oiwa
Mitsutomo Kohno
Masayuki Iwazaki
Publication date: 01-07-2018
Publisher: Springer Japan
Published in: General Thoracic and Cardiovascular Surgery / Issue 7/2018
Print ISSN: 1863-6705
Electronic ISSN: 1863-6713
DOI: https://doi.org/10.1007/s11748-017-0871-0

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A surgical case of methotrexate-associated lymphomatoid granuloma

Abstract

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Abstract

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