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01-08-2021 | Obesity | Original Contributions

The Effect of Bariatric Surgery on Metabolic Syndrome: A Three-center Experience in Saudi Arabia

Authors: Abdulrahman O. Alomar, Mohammed F. Shaheen, Abdallh S. Almaneea, Eyad K. Althaqeb, Ziyad M. Alshahrani, Yazeed A. Jarman, Sultan Alhabdan

Published in: Obesity Surgery | Issue 8/2021

Abstract

Purpose

The prevalence of metabolic syndrome (MetS) increases in parallel with the increasing incidence of obesity. Hence, bariatric surgery is potentially curative in obese patients with MetS. We aim to measure the effect of bariatric surgery as well as the potential factors leading to MetS resolution in the Saudi population.

Methods

A retrospective review of three tertiary care centers in Saudi Arabia was done. We identified 386 patients who have MetS and underwent bariatric surgery during the period between January 2016 and December 2018. After exclusion of patients with insufficient follow-up, data from 275 patients was analyzed. MetS diagnosis, persistence, and resolution were determined using the International Diabetes Federation consensus worldwide definition.

Results

MetS resolution was achieved in 78%, 79%, 73%, and 82% at 1, 2, 3, and 4 years after bariatric surgery, respectively. Accumulatively, 80% achieved MetS resolution with an average follow-up period of two and a half years. Patients who experienced resolution had younger age, lower BMI, lower systolic blood pressure, lower triglycerides, lower fasting plasma glucose, and lower HbA1c preoperatively in addition to a higher percentage of excess weight loss after bariatric surgery when compared to those who had persistence of MetS.

Conclusion

More than three fourths of patients with MetS achieved resolution after bariatric surgery. Certain patient characteristics, such as young age and higher excess weight loss postoperatively, were associated with a higher chance of MetS resolution.

Graphical abstract

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Title: The Effect of Bariatric Surgery on Metabolic Syndrome: A Three-center Experience in Saudi Arabia
Authors: Abdulrahman O. Alomar
Mohammed F. Shaheen
Abdallh S. Almaneea
Eyad K. Althaqeb
Ziyad M. Alshahrani
Yazeed A. Jarman
Sultan Alhabdan
Publication date: 01-08-2021
Publisher: Springer US
Keywords: Obesity
Obesity
Sleeve Gastrectomy
Bariatric Surgery
Bariatric Surgery
Published in: Obesity Surgery / Issue 8/2021
Print ISSN: 0960-8923
Electronic ISSN: 1708-0428
DOI: https://doi.org/10.1007/s11695-021-05461-3

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

The Effect of Bariatric Surgery on Metabolic Syndrome: A Three-center Experience in Saudi Arabia

Abstract

Purpose

Methods

Results

Conclusion

Graphical abstract

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

Graphical abstract

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