Skip to main content
Top
Published in: Obesity Surgery 6/2021

Open Access 01-06-2021 | Obesity | Original Contributions

Bariatric-Metabolic Surgery Utilisation in Patients With and Without Diabetes: Data from the IFSO Global Registry 2015–2018

Authors: Richard Welbourn, Marianne Hollyman, Robin Kinsman, John Dixon, Ricardo Cohen, John Morton, Amir Ghaferi, Kelvin Higa, Johan Ottosson, Francois Pattou, Salman Al-Sabah, Merhan Anvari, Jacques Himpens, Ronald Liem, Villy Våge, Peter Walton, Wendy Brown, Lilian Kow

Published in: Obesity Surgery | Issue 6/2021

Login to get access

Abstract

Background

Comparative international practice of patients undergoing bariatric-metabolic surgery for type 2 diabetes mellitus (T2DM) is unknown. We aimed to ascertain baseline age, sex, body mass index (BMI) and types of operations performed for patients with T2DM submitted to the IFSO Global Registry.

Materials and Methods

Cross-sectional analysis of patients having primary surgery in 2015–2018 for countries with ≥90% T2DM data completion and ≥ 1000 submitted records.

Results

Fifteen countries including 11 national registries met the inclusion criteria. The rate of T2DM was 24.2% (99,537 of 411,581 patients, country range 12.0–55.1%) and 77.1% of all patients were women. In every country, patients with T2DM were older than those without T2DM (overall mean age 49.2 [SD 11.4] years vs 41.8 [11.9] years, all p < 0.001). Men were more likely to have T2DM than women, odds ratio (OR) 1.68 (95% CI 1.65–1.71), p < 0.001. Men showed higher rates of T2DM for BMI <35 kg/m2 compared to BMI ≥35.0 kg/m2, OR 2.76 (2.52–3.03), p < 0.001. This was not seen in women, OR 0.78 (0.73–0.83), p < 0.001. Sleeve gastrectomy was the commonest operation overall, but less frequent for patients with T2DM, patients with T2DM 54.9% vs without T2DM 65.8%, OR 0.63 (0.63–0.64), p < 0.001. Twelve out of 15 countries had higher proportions of gastric bypass compared to non-bypass operations for T2DM, OR 1.70 (1.67–1.72), p < 0.001.

Conclusion

Patients with T2DM had different characteristics to those without T2DM. Older men were more likely to have T2DM, with higher rates of BMI <35 kg/m2 and increased likelihood of food rerouting operations.
Appendix
Available only for authorised users
Literature
3.
go back to reference Salminen P, Helmiö M, Ovaska J, et al. Effect of laparoscopic sleeve gastrectomy vs laparoscopic Roux-en-Y gastric bypass on weight loss at 5 years among patients with morbid obesity: the SLEEVEPASS randomized clinical trial. JAMA. 2018;319(3):241–54. Salminen P, Helmiö M, Ovaska J, et al. Effect of laparoscopic sleeve gastrectomy vs laparoscopic Roux-en-Y gastric bypass on weight loss at 5 years among patients with morbid obesity: the SLEEVEPASS randomized clinical trial. JAMA. 2018;319(3):241–54.
4.
go back to reference Peterli R, Wölnerhanssen BK, Peters T, et al. Effect of laparoscopic sleeve gastrectomy vs laparoscopic Roux-en-Y gastric bypass on weight loss in patients with morbid obesity: the SM-BOSS randomized clinical trial. JAMA. 2018;319(3):255–65. https://doi.org/10.1001/jama.2017.20897. Peterli R, Wölnerhanssen BK, Peters T, et al. Effect of laparoscopic sleeve gastrectomy vs laparoscopic Roux-en-Y gastric bypass on weight loss in patients with morbid obesity: the SM-BOSS randomized clinical trial. JAMA. 2018;319(3):255–65. https://​doi.​org/​10.​1001/​jama.​2017.​20897.
5.
go back to reference Hofsø D, Fatima F, Borgeraas H, et al. Gastric bypass versus sleeve gastrectomy in patients with type 2 diabetes (Oseberg): a singlecenter, triple-blind, randomized controlled trial. Lancet Diabetes Endocrinol. 2019;7(12):912–24. Hofsø D, Fatima F, Borgeraas H, et al. Gastric bypass versus sleeve gastrectomy in patients with type 2 diabetes (Oseberg): a singlecenter, triple-blind, randomized controlled trial. Lancet Diabetes Endocrinol. 2019;7(12):912–24.
6.
go back to reference Avenell A, Robertson C, Skea Z, et al. Bariatric surgery, lifestyle interventions and orlistat for severe obesity: the REBALANCE mixed-methods systematic review and economic evaluation. Health Technol Assess. 2018;22(68):1–246. https://doi.org/10.3310/hta22680. Avenell A, Robertson C, Skea Z, et al. Bariatric surgery, lifestyle interventions and orlistat for severe obesity: the REBALANCE mixed-methods systematic review and economic evaluation. Health Technol Assess. 2018;22(68):1–246. https://​doi.​org/​10.​3310/​hta22680.
7.
go back to reference Borgeraas H, Hofsø D, Hertel JK, et al. Comparison of the effect of Roux-en-Y gastric bypass and sleeve gastrectomy on remission of type 2 diabetes: a systematic review and meta-analysis of randomized controlled trials. Obes Rev. 2020;21(6):e13011. https://doi.org/10.1111/obr.13011. Borgeraas H, Hofsø D, Hertel JK, et al. Comparison of the effect of Roux-en-Y gastric bypass and sleeve gastrectomy on remission of type 2 diabetes: a systematic review and meta-analysis of randomized controlled trials. Obes Rev. 2020;21(6):e13011. https://​doi.​org/​10.​1111/​obr.​13011.
8.
go back to reference Dixon JB, Zimmet P, Alberti KG, et al. Bariatric surgery: an IDF statement for obese Type 2 diabetes. Diabet Med. 2011;28(6):628–42. Dixon JB, Zimmet P, Alberti KG, et al. Bariatric surgery: an IDF statement for obese Type 2 diabetes. Diabet Med. 2011;28(6):628–42.
9.
go back to reference Stegenga H, Haines A, Jones K, et al. Identification, assessment, and management of overweight and obesity: summary of updated NICE guidance. BMJ. 2014;349:g6608. Stegenga H, Haines A, Jones K, et al. Identification, assessment, and management of overweight and obesity: summary of updated NICE guidance. BMJ. 2014;349:g6608.
10.
go back to reference Welbourn R, Hopkins J, Dixon JB, et al. Commissioning guidance for weight assessment and management in adults and children with severe complex obesity. Obes Rev. 2018;19:14–27. Welbourn R, Hopkins J, Dixon JB, et al. Commissioning guidance for weight assessment and management in adults and children with severe complex obesity. Obes Rev. 2018;19:14–27.
11.
13.
go back to reference Buchwald H, Varco RL. Metabolic surgery (modern surgical monographs): Grune & Stratton; 1978. ISBN 10: 0808910779 / ISBN 13: 9780808910770 Buchwald H, Varco RL. Metabolic surgery (modern surgical monographs): Grune & Stratton; 1978. ISBN 10: 0808910779 / ISBN 13: 9780808910770
15.
go back to reference Xia Q, Campbell JA, Ahmad H, et al. Bariatric surgery is a cost-saving treatment for obesity-a comprehensive meta-analysis and updated systematic review of health economic evaluations of bariatric surgery. Obes Rev. 2020;21(1):e12932. Xia Q, Campbell JA, Ahmad H, et al. Bariatric surgery is a cost-saving treatment for obesity-a comprehensive meta-analysis and updated systematic review of health economic evaluations of bariatric surgery. Obes Rev. 2020;21(1):e12932.
17.
go back to reference Welbourn R, Pournaras DJ, Dixon J, et al. Bariatric surgery worldwide: baseline demographic description and one-year outcomes from the Second IFSO Global Registry Report 2013-2015. Obes Surg. 2018;28:313–22. Welbourn R, Pournaras DJ, Dixon J, et al. Bariatric surgery worldwide: baseline demographic description and one-year outcomes from the Second IFSO Global Registry Report 2013-2015. Obes Surg. 2018;28:313–22.
19.
go back to reference Buchwald H, Williams SE. Bariatric surgery worldwide 2003. Obes Surg 2004;14:1157-64 Buchwald H, Williams SE. Bariatric surgery worldwide 2003. Obes Surg 2004;14:1157-64
20.
go back to reference Buchwald H, Oien DM. Metabolic/bariatric surgery Worldwide 2008. Obes Surg. 2009;19:1605–11. Buchwald H, Oien DM. Metabolic/bariatric surgery Worldwide 2008. Obes Surg. 2009;19:1605–11.
21.
go back to reference Buchwald H, Oien DM. Metabolic/bariatric surgery worldwide 2011. Obes Surg. 2013;23:427–36. Buchwald H, Oien DM. Metabolic/bariatric surgery worldwide 2011. Obes Surg. 2013;23:427–36.
22.
go back to reference Angrisani L, Santonicola A, Iovino P, et al. Bariatric surgery worldwide 2013. Obes Surg. 2015;25:1822–32. Angrisani L, Santonicola A, Iovino P, et al. Bariatric surgery worldwide 2013. Obes Surg. 2015;25:1822–32.
23.
go back to reference Angrisani L, Santonicola A, Iovino P, et al. IFSO worldwide survey 2016: primary, endoluminal, and revisional procedures. Obes Surg. 2018;28:3783–94. Angrisani L, Santonicola A, Iovino P, et al. IFSO worldwide survey 2016: primary, endoluminal, and revisional procedures. Obes Surg. 2018;28:3783–94.
24.
go back to reference Welbourn R, Gagner M, Naslund I, et al. First IFSO Global Registry Report 2014. Henley-on-Thames: Dendrite Clinical Systems Ltd; 2014. ISBN 978-0-9568154-9-1 Welbourn R, Gagner M, Naslund I, et al. First IFSO Global Registry Report 2014. Henley-on-Thames: Dendrite Clinical Systems Ltd; 2014. ISBN 978-0-9568154-9-1
29.
go back to reference Martin M, Beekley A, Kjorstad R, et al. Socioeconomic disparities in eligibility and access to bariatric surgery: a national population-based analysis. Surg Obes Relat Dis. 2010;6:8e15. Martin M, Beekley A, Kjorstad R, et al. Socioeconomic disparities in eligibility and access to bariatric surgery: a national population-based analysis. Surg Obes Relat Dis. 2010;6:8e15.
30.
go back to reference Kumar SB, Hamilton BC, Wood SG, et al. Is laparoscopic sleeve gastrectomy safer than laparoscopic gastric bypass? A comparison of 30-day complications using the MBSAQIP data registry. Surg Obes Relat Dis. 2018;14:264–9. Kumar SB, Hamilton BC, Wood SG, et al. Is laparoscopic sleeve gastrectomy safer than laparoscopic gastric bypass? A comparison of 30-day complications using the MBSAQIP data registry. Surg Obes Relat Dis. 2018;14:264–9.
31.
32.
go back to reference Marso SP, Daniels GH, Brown-Frandsen K, et al. Liraglutide and cardiovascular outcomes in type 2 diabetes. NEJM. 2016;375:311–22. Marso SP, Daniels GH, Brown-Frandsen K, et al. Liraglutide and cardiovascular outcomes in type 2 diabetes. NEJM. 2016;375:311–22.
33.
go back to reference Pi-Sunyer X, Astrup A, Fujioka K, et al. A randomized, controlled trial of 3.0 mg of liraglutide in weight management. NEJM. 2015;373:11–22. Pi-Sunyer X, Astrup A, Fujioka K, et al. A randomized, controlled trial of 3.0 mg of liraglutide in weight management. NEJM. 2015;373:11–22.
34.
go back to reference Dixon JB. Regional differences in the coverage and uptake of bariatric-metabolic surgery: a focus on type 2 diabetes. Surg Obes Relat Dis. 2016;12(6):1171–7. Dixon JB. Regional differences in the coverage and uptake of bariatric-metabolic surgery: a focus on type 2 diabetes. Surg Obes Relat Dis. 2016;12(6):1171–7.
36.
go back to reference Ng M, Fleming T, Robinson M, et al. Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2014;384:766–81. Ng M, Fleming T, Robinson M, et al. Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2014;384:766–81.
38.
Metadata
Title
Bariatric-Metabolic Surgery Utilisation in Patients With and Without Diabetes: Data from the IFSO Global Registry 2015–2018
Authors
Richard Welbourn
Marianne Hollyman
Robin Kinsman
John Dixon
Ricardo Cohen
John Morton
Amir Ghaferi
Kelvin Higa
Johan Ottosson
Francois Pattou
Salman Al-Sabah
Merhan Anvari
Jacques Himpens
Ronald Liem
Villy Våge
Peter Walton
Wendy Brown
Lilian Kow
Publication date
01-06-2021
Publisher
Springer US
Published in
Obesity Surgery / Issue 6/2021
Print ISSN: 0960-8923
Electronic ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-021-05280-6

Other articles of this Issue 6/2021

Obesity Surgery 6/2021 Go to the issue