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Obesity Surgery

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01-01-2021 | Sleeve Gastrectomy | Original Contributions

Thyroid Hormone Changes After Sleeve Gastrectomy With and Without Antral Preservation

Authors: Kerem Karaman, Kaan Mansıroglu, Ozkan Subasi, Aytac Biricik, Hakan Yirgin, Elif Kose, Metin Ercan

Published in: Obesity Surgery | Issue 1/2021

Abstract

Background

The effect of bariatric surgery on thyroid hormone changes yielded inconsistent results. The aim of the present study was to assess the change of thyroid hormone levels following laparoscopic sleeve gastrectomy (LSG), with or without antral preservation (AP).

Methods

Thyroid hormones (TSH, FT3, FT4) were examined preoperatively, at the end of the first postoperative month, and first postoperative year. Secondly, antral resection (AR) and AP were compared at inducing weight loss and thereby affecting thyroid hormone levels.

Results

Euthyroid obese patients (86 female/20 male) underwent LSG. Of these, 58 patients underwent AR and 48 patients AP. The mean FT3 levels significantly decreased both in the first postoperative month and the first year (P < 0.001), whereas mean TSH levels decreased significantly in the first postoperative year (P < 0.001). FT4 levels remained nearly unchanged (P = 0.517). Postoperative first year body mass index (BMI) loss, excess BMI loss percentile (%EBMIL), and total body weight loss percentile (%TWL) were significantly higher in AR group than the AP group (P ≤ 0.01). When the change in thyroid hormone levels was analyzed by pyloric distance according to time periods, no significant difference was found in TSH and FT4 levels (P > 0.05); however, reduction in FT3 levels was significantly greater in patients with AR than in AP patients (P = 0.028).

Conclusion

LSG promotes significant reduction in TSH and FT3 levels, whereas FT4 levels remain unchanged. LSG with AR provides more weight loss in short term and appears to be more effective at lowering FT3 levels.

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Title: Thyroid Hormone Changes After Sleeve Gastrectomy With and Without Antral Preservation
Authors: Kerem Karaman
Kaan Mansıroglu
Ozkan Subasi
Aytac Biricik
Hakan Yirgin
Elif Kose
Metin Ercan
Publication date: 01-01-2021
Publisher: Springer US
Keywords: Sleeve Gastrectomy
Bariatric Surgery
Bariatric Surgery
Published in: Obesity Surgery / Issue 1/2021
Print ISSN: 0960-8923
Electronic ISSN: 1708-0428
DOI: https://doi.org/10.1007/s11695-020-04896-4

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Thyroid Hormone Changes After Sleeve Gastrectomy With and Without Antral Preservation

Abstract

Background

Methods

Results

Conclusion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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