Personalized Nutrition for Management of Micronutrient Deficiency—Literature Review in Non-bariatric Populations and Possible Utility in Bariatric Cohort

1.

Ogden CL, Carroll MD, Kit BK, et al. Prevalence of childhood and adult obesity in the United States, 2011–2012. JAMA. 2014;311(8):806–14. https://doi.org/10.1001/jama.2014.732.CrossRefPubMedPubMedCentral

2.

Bloomberg RD, Fleishman A, Nalle JE, et al. Nutritional deficiencies following bariatric surgery: what have we learned? Obes Surg. 2005;15(2):145–54. https://doi.org/10.1381/0960892053268264.CrossRefPubMed

3.

Sawaya RA, Jaffe J, Friedenberg L, et al. Vitamin, mineral, and drug absorption following bariatric surgery. Curr Drug Metab. 2012;13(9):1345–55.CrossRef

4.

Ahmad DS, Esmadi M, Hammad H. Malnutrition secondary to non-compliance with vitamin and mineral supplements after gastric bypass surgery: What can we do about it? Am J Case Rep. 2012;13:209–13. https://doi.org/10.12659/AJCR.883335.CrossRefPubMedPubMedCentral

5.

Mechanick JI, Apovian C, Brethauer S, et al. Clinical practice guidelines for the perioperative nutrition, metabolic, and nonsurgical support of patients undergoing bariatric procedures - 2019 update: cosponsored by American Association of Clinical Endocrinologists/American College of Endocrinology, the Obesity Society, American Society for Metabolic & Bariatric Surgery, Obesity Medicine Association, and American Society of Anesthesiologists - Executive Summary. Endocr Pract. 2019;25(12):1346–59. https://doi.org/10.4158/GL-2019-0406.CrossRefPubMed

6.

Lombardo M, Franchi A, Padua E, et al. Potential nutritional deficiencies in obese subjects 5 years after bariatric surgery. Bariatric Surgical Practice and Patient Care. 2019;14(3):125–30.CrossRef

7.

Mahlay NF, Verka LG, Thomsen K, et al. Vitamin D status before Roux-en-Y and efficacy of prophylactic and therapeutic doses of vitamin D in patients after Roux-en-Y gastric bypass surgery. Obes Surg. 2009;19(5):590–4. https://doi.org/10.1007/s11695-008-9698-1.CrossRefPubMed

8.

Ferguson LR, De Caterina R, Görman U, et al. Guide and position of the International Society of Nutrigenetics/Nutrigenomics on personalised nutrition: part 1 - fields of precision nutrition. J Nutrigenet Nutrigenomics. 2016;9(1):12–27. https://doi.org/10.1159/000445350.CrossRefPubMed

9.

Trovato GM. Behavior, nutrition and lifestyle in a comprehensive health and disease paradigm: skills and knowledge for a predictive, preventive and personalized medicine. EPMA J. 2012;3(1):8. https://doi.org/10.1007/s13167-012-0141-2.CrossRefPubMedPubMedCentral

10.

Fallaize R, Macready AL, Butler LT, et al. An insight into the public acceptance of nutrigenomic-based personalised nutrition. Nutr Res Rev. 2013;26(1):39–48. https://doi.org/10.1017/S0954422413000024.CrossRefPubMed

11.

Crovesy L, Rosado EL. Interaction between genes involved in energy intake regulation and diet in obesity. Nutrition. 2019;67–68:110547. https://doi.org/10.1016/j.nut.2019.06.027.CrossRefPubMed

12.

Nielsen DE, El-Sohemy A. A randomized trial of genetic information for personalized nutrition. Genes Nutr. 2012;7(4):559–66. https://doi.org/10.1007/s12263-012-0290-x.CrossRefPubMedPubMedCentral

13.

Maher B. Nature readers flirt with personal genomics. Nature. 2011;478(7367):19. https://doi.org/10.1038/478019a.CrossRefPubMed

14.

Bloss CS, Schork NJ, Topol EJ. Effect of direct-to-consumer genomewide profiling to assess disease risk. N Engl J Med. 2011;364(6):524–34. https://doi.org/10.1056/NEJMoa1011893.CrossRefPubMedPubMedCentral

15.

Brolin RE, LaMarca LB, Kenler HA, et al. Malabsorptive gastric bypass in patients with superobesity. J Gastrointest Surg. 2002;6(2):195–203. discussion 4-5CrossRef

16.

Berger JR. The neurological complications of bariatric surgery. Arch Neurol. 2004;61(8):1185–9. https://doi.org/10.1001/archneur.61.8.1185.CrossRefPubMed

17.

Shenkin A. Micronutrients in health and disease. Postgrad Med J. 2006;82(971):559–67. https://doi.org/10.1136/pgmj.2006.047670.CrossRefPubMedPubMedCentral

18.

Geissler C, Powers H. Fundamentals of human nutrition E-book: for students and practitioners in health sciences: Churchill Livingstone Elsevier; 2009. 324 p.

19.

Reddy VS, Palika R, Ismail A, et al. Nutrigenomics: Opportunities & challenges for public health nutrition. Indian J Med Res. 2018;148(5):632–41. https://doi.org/10.4103/ijmrIJMR_1738_18.CrossRefPubMedPubMedCentral

20.

Lister Hill National Center for Biomedical Communications. Genetics home reference [unspecified]. Bethesda, MD: National Library of Medicine, National Institutes of Health,; 2003. Available from: http://ghr.nlm.nih.gov/.

21.

Sharp P, Srai SK. Molecular mechanisms involved in intestinal iron absorption. World J Gastroenterol. 2007;13(35):4716–24. https://doi.org/10.3748/wjg.v13.i35.4716.CrossRefPubMedPubMedCentral

22.

Kluijtmans LA, van den Heuvel LP, Boers GH, et al. Molecular genetic analysis in mild hyperhomocysteinemia: a common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease. Am J Hum Genet. 1996;58(1):35–41.PubMedPubMedCentral

23.

Borel P, Desmarchelier C. Bioavailability of fat-soluble vitamins and phytochemicals in humans: effects of genetic variation. Annu Rev Nutr. 2018;38:69–96. https://doi.org/10.1146/annurev-nutr-082117-051628.CrossRefPubMed

24.

Dib MJ, Elliott R, Ahmadi KR. A critical evaluation of results from genome-wide association studies of micronutrient status and their utility in the practice of precision nutrition. Br J Nutr. 2019;122(2):121–30. https://doi.org/10.1017/S0007114519001119.CrossRefPubMed

25.

Desmarchelier C, Borel P, Goncalves A, et al. A combination of single-nucleotide polymorphisms is associated with interindividual variability in cholecalciferol bioavailability in healthy men. J Nutr. 2016;146(12):2421–8. https://doi.org/10.3945/jn.116.237115.CrossRefPubMed

26.

Nissen J, Rasmussen LB, Ravn-Haren G, et al. Common variants in CYP2R1 and GC genes predict vitamin D concentrations in healthy Danish children and adults. PLoS One. 2014;9(2):e89907. https://doi.org/10.1371/journal.pone.0089907.CrossRefPubMedPubMedCentral

27.

Barry EL, Rees JR, Peacock JL, et al. Genetic variants in CYP2R1, CYP24A1, and VDR modify the efficacy of vitamin D3 supplementation for increasing serum 25-hydroxyvitamin D levels in a randomized controlled trial. J Clin Endocrinol Metab. 2014;99(10):E2133–7. https://doi.org/10.1210/jc.2014-1389.CrossRefPubMedPubMedCentral

28.

NIH. Genetics Home Reference [cited 2019]. Available from: https://ghr.nlm.nih.gov/.

29.

Surendran S, Adaikalakoteswari A, Saravanan P, et al. An update on vitamin B12-related gene polymorphisms and B12 status. Genes Nutr. 2018;13:2. Epub 2018/02/06. https://doi.org/10.1186/s12263-018-0591-9.CrossRefPubMedPubMedCentral

30.

Zinck JW, de Groh M, MacFarlane AJ. Genetic modifiers of folate, vitamin B-12, and homocysteine status in a cross-sectional study of the Canadian population. Am J Clin Nutr. 2015;101(6):1295–304. Epub 2015/05/06. https://doi.org/10.3945/ajcn.115.107219.CrossRefPubMed

31.

Hazra A, Kraft P, Selhub J, et al. Common variants of FUT2 are associated with plasma vitamin B12 levels. Nat Genet. 2008;40(10):1160–2. https://doi.org/10.1038/ng.210.CrossRefPubMedPubMedCentral

32.

Tanaka T, Scheet P, Giusti B, et al. Genome-wide association study of vitamin B6, vitamin B12, folate, and homocysteine blood concentrations. Am J Hum Genet. 2009;84(4):477–82. https://doi.org/10.1016/j.ajhg.2009.02.011.CrossRefPubMedPubMedCentral

33.

Frosst P, Blom HJ, Milos R, et al. A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase. Nat Genet. 1995;10(1):111–3. Epub 1995/05/01. https://doi.org/10.1038/ng0595-111.CrossRefPubMed

34.

Bagley PJ, Selhub J. A common mutation in the methylenetetrahydrofolate reductase gene is associated with an accumulation of formylated tetrahydrofolates in red blood cells. Proc Natl Acad Sci U S A. 1998;95(22):13217–20. https://doi.org/10.1073/pnas.95.22.13217.CrossRefPubMedPubMedCentral

35.

Zhang K, Huentelman MJ, Rao F, et al. Genetic implication of a novel thiamine transporter in human hypertension. J Am Coll Cardiol. 2014;63(15):1542–55. Epub 2014/02/05. https://doi.org/10.1016/j.jacc.2014.01.007.CrossRefPubMedPubMedCentral

36.

Mikstiene V, Songailiene J, Byckova J, et al. Thiamine responsive megaloblastic anemia syndrome: a novel homozygous SLC19A2 gene mutation identified. Am J Med Genet A. 2015;167(7):1605–9. Epub 2015/02/23. https://doi.org/10.1002/ajmg.a.37015.CrossRefPubMed

37.

Pichler I, Minelli C, Sanna S, et al. Identification of a common variant in the TFR2 gene implicated in the physiological regulation of serum iron levels. Hum Mol Genet. 2011;20(6):1232–40. https://doi.org/10.1093/hmg/ddq552.CrossRefPubMed

38.

Blanco-Rojo R, Baeza-Richer C, López-Parra AM, et al. Four variants in transferrin and HFE genes as potential markers of iron deficiency anaemia risk: an association study in menstruating women. Nutr Metab (Lond). 2011;8:69. https://doi.org/10.1186/1743-7075-8-69.CrossRef

39.

Gemmel K, Santry HP, Prachand VN, et al. Vitamin D deficiency in preoperative bariatric surgery patients. Surg Obes Relat Dis. 2009;5(1):54–9. https://doi.org/10.1016/j.soard.2008.07.008.CrossRefPubMed

40.

Bischoff-Ferrari HA, Willett WC, Wong JB, et al. Fracture prevention with vitamin D supplementation: a meta-analysis of randomized controlled trials. JAMA. 2005;293(18):2257–64. https://doi.org/10.1001/jama.293.18.2257.CrossRefPubMed

41.

Holick MF. High prevalence of vitamin D inadequacy and implications for health. Mayo Clin Proc. 2006;81(3):353–73. https://doi.org/10.4065/81.3.353.CrossRefPubMed

42.

Chakhtoura MT, Nakhoul NN, Shawwa K, et al. Hypovitaminosis D in bariatric surgery: A systematic review of observational studies. Metabolism. 2016;65(4):574–85. https://doi.org/10.1016/j.metabol.2015.12.004.CrossRefPubMed

43.

Peterson LA, Zeng X, Caufield-Noll CP, et al. Vitamin D status and supplementation before and after bariatric surgery: a comprehensive literature review. Surg Obes Relat Dis. 2016;12(3):693–702. https://doi.org/10.1016/j.soard.2016.01.001.CrossRefPubMed

44.

Afzal S, Brøndum-Jacobsen P, Bojesen SE, et al. Genetically low vitamin D concentrations and increased mortality: Mendelian randomisation analysis in three large cohorts. BMJ. 2014;349:g6330. https://doi.org/10.1136/bmj.g6330.CrossRefPubMedPubMedCentral

45.

Shea MK, Benjamin EJ, Dupuis J, et al. Genetic and non-genetic correlates of vitamins K and D. Eur J Clin Nutr. 2009;63(4):458–64. https://doi.org/10.1038/sj.ejcn.1602959.CrossRefPubMed

46.

Waterhouse M, Tran B, Armstrong BK, et al. Environmental, personal, and genetic determinants of response to vitamin D supplementation in older adults. J Clin Endocrinol Metab. 2014;99(7):E1332–40. https://doi.org/10.1210/jc.2013-4101.CrossRefPubMed

47.

Didriksen A, Grimnes G, Hutchinson MS, et al. The serum 25-hydroxyvitamin D response to vitamin D supplementation is related to genetic factors, BMI, and baseline levels. Eur J Endocrinol. 2013;169(5):559–67. https://doi.org/10.1530/EJE-13-0233.CrossRefPubMed

48.

Quinlivan EP, McPartlin J, McNulty H, et al. Importance of both folic acid and vitamin B12 in reduction of risk of vascular disease. Lancet. 2002;359(9302):227–8. https://doi.org/10.1016/s0140-6736(02)07439-1.CrossRefPubMed

49.

Hin H, Clarke R, Sherliker P, et al. Clinical relevance of low serum vitamin B12 concentrations in older people: the Banbury B12 study. Age Ageing. 2006;35(4):416–22. https://doi.org/10.1093/ageing/afl033.CrossRefPubMed

50.

O'Leary F, Samman S. Vitamin B12 in health and disease. Nutrients. 2010;2(3):299–316. https://doi.org/10.3390/nu2030299.CrossRefPubMedPubMedCentral

51.

Lechner K, Födinger M, Grisold W, et al. Vitamin B12 deficiency. New data on an old theme. Wien Klin Wochenschr. 2005;117(17):579–91. https://doi.org/10.1007/s00508-005-0406-z.CrossRefPubMed

52.

Collaboration HLT. Dose-dependent effects of folic acid on blood concentrations of homocysteine: a meta-analysis of the randomized trials. Am J Clin Nutr. 2005;82(4):806–12. https://doi.org/10.1093/ajcn/82.4.806.CrossRef

53.

Spence JD, Bang H, Chambless LE, et al. Vitamin intervention for stroke prevention trial: an efficacy analysis. Stroke. 2005;36(11):2404–9. https://doi.org/10.1161/01.STR.0000185929.38534.f3.CrossRefPubMed

54.

Arendt JF, Nexo E. Unexpected high plasma cobalamin: proposal for a diagnostic strategy. Clin Chem Lab Med. 2013;51(3):489–96. https://doi.org/10.1515/cclm-2012-0545.CrossRefPubMed

55.

Arendt JF, Pedersen L, Nexo E, et al. Elevated plasma vitamin B12 levels as a marker for cancer: a population-based cohort study. J Natl Cancer Inst. 2013;105(23):1799–805. https://doi.org/10.1093/jnci/djt315.CrossRefPubMedPubMedCentral

56.

Stabler SP. Vitamin B12 deficiency. N Engl J Med. 2013;368(21):2041–2. https://doi.org/10.1056/NEJMc1304350.CrossRefPubMed

57.

Flancbaum L, Belsley S, Drake V, et al. Preoperative nutritional status of patients undergoing Roux-en-Y gastric bypass for morbid obesity. J Gastrointest Surg. 2006;10(7):1033–7. https://doi.org/10.1016/j.gassur.2006.03.004.CrossRefPubMed

58.

Mehaffey JH, Mehaffey RL, Mullen MG, et al. Nutrient deficiency 10 years following Roux-en-Y gastric bypass: who’s responsible? Obes Surg. 2017;27(5):1131–6. https://doi.org/10.1007/s11695-016-2364-0.CrossRefPubMedPubMedCentral

59.

Skroubis G, Sakellaropoulos G, Pouggouras K, et al. Comparison of nutritional deficiencies after Roux-en-Y gastric bypass and after biliopancreatic diversion with Roux-en-Y gastric bypass. Obes Surg. 2002;12(4):551–8. https://doi.org/10.1381/096089202762252334.CrossRefPubMed

60.

Vargas-Ruiz AG, Hernández-Rivera G, Herrera MF. Prevalence of iron, folate, and vitamin B12 deficiency anemia after laparoscopic Roux-en-Y gastric bypass. Obes Surg. 2008;18(3):288–93. https://doi.org/10.1007/s11695-007-9310-0.CrossRefPubMed

61.

Quadros EV. Advances in the understanding of cobalamin assimilation and metabolism. Br J Haematol. 2010;148(2):195–204. Epub 2009/10/12. https://doi.org/10.1111/j.1365-2141.2009.07937.x.CrossRefPubMed

62.

Li N, Rosenblatt DS, Kamen BA, et al. Identification of two mutant alleles of transcobalamin II in an affected family. Hum Mol Genet. 1994;3(10):1835–40. https://doi.org/10.1093/hmg/3.10.1835.CrossRefPubMed

63.

Coelho D, Suormala T, Stucki M, et al. Gene identification for the cblD defect of vitamin B12 metabolism. N Engl J Med. 2008;358(14):1454–64. https://doi.org/10.1056/NEJMoa072200.CrossRefPubMed

64.

Nilsson SE, Read S, Berg S, et al. Heritabilities for fifteen routine biochemical values: findings in 215 Swedish twin pairs 82 years of age or older. Scand J Clin Lab Invest. 2009;69(5):562–9. https://doi.org/10.1080/00365510902814646.CrossRefPubMed

65.

Grarup N, Sulem P, Sandholt CH, et al. Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets. PLoS Genet. 2013;9(6):e1003530. Epub 2013/06/06. https://doi.org/10.1371/journal.pgen.1003530.CrossRefPubMedPubMedCentral

66.

Johnston J, Bollekens J, Allen RH, et al. Structure of the cDNA encoding transcobalamin I, a neutrophil granule protein. J Biol Chem. 1989;264(27):15754–7.PubMed

67.

Stanisławska-Sachadyn A, Woodside JV, Sayers CM, et al. The transcobalamin (TCN2) 776C>G polymorphism affects homocysteine concentrations among subjects with low vitamin B(12) status. Eur J Clin Nutr. 2010;64(11):1338–43. Epub 2010/09/01. https://doi.org/10.1038/ejcn.2010.157.CrossRefPubMed

68.

Andrew T, Gill R, Gillham-Nasenya I, et al. Unravelling the basis of variability in cobalamin levels in the general population. Br J Nutr. 2013;110(9):1672–9. Epub 2013/04/29. https://doi.org/10.1017/S0007114513000974.CrossRefPubMed

69.

Matteini AM, Walston JD, Bandeen-Roche K, et al. Transcobalamin-II variants, decreased vitamin B12 availability and increased risk of frailty. J Nutr Health Aging. 2010;14(1):73–7. https://doi.org/10.1007/s12603-010-0013-1.CrossRefPubMedPubMedCentral

70.

Nazki FH, Sameer AS, Ganaie BA. Folate: metabolism, genes, polymorphisms and the associated diseases. Gene. 2014;533(1):11–20. Epub 2013/10/01. https://doi.org/10.1016/j.gene.2013.09.063.CrossRefPubMed

71.

Bailey LB, Gregory JF. Folate metabolism and requirements. J Nutr. 1999;129(4):779–82. https://doi.org/10.1093/jn/129.4.779.CrossRefPubMed

72.

Hubner RA, Houlston RS. Folate and colorectal cancer prevention. Br J Cancer. 2009;100(2):233–9. Epub 2008/12/16. doi: https://doi.org/10.1038/sj.bjc.6604823.

73.

Blom HJ, Smulders Y. Overview of homocysteine and folate metabolism. With special references to cardiovascular disease and neural tube defects. J Inherit Metab Dis. 2011;34(1):75–81. Epub 2010/09/04. https://doi.org/10.1007/s10545-010-9177-4.CrossRefPubMed

74.

Smithells RW, Sheppard S, Schorah CJ. Vitamin deficiencies and neural tube defects. Arch Dis Child. 1976;51(12):944–50. https://doi.org/10.1136/adc.51.12.944.CrossRefPubMedPubMedCentral

75.

Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. MRC Vitamin Study Research Group. Lancet. 1991;338(8760):131–7.

76.

Komorniak N, Szczuko M, Kowalewski B, et al. Nutritional deficiencies, bariatric surgery, and serum homocysteine level: review of current literature. Obes Surg. 2019;29(11):3735–42. https://doi.org/10.1007/s11695-019-04100-2.CrossRefPubMed

77.

Eldibany MM, Caprini JA. Hyperhomocysteinemia and thrombosis: an overview. Arch Pathol Lab Med. 2007;131(6):872–84. https://doi.org/10.1043/1543-2165(2007)131[872:HATAO]2.0.CO;2.CrossRefPubMed

78.

Clarke R, Halsey J, Lewington S, et al. Effects of lowering homocysteine levels with B vitamins on cardiovascular disease, cancer, and cause-specific mortality: meta-analysis of 8 randomized trials involving 37 485 individuals. Arch Intern Med. 2010;170(18):1622–31. https://doi.org/10.1001/archinternmed.2010.348.CrossRefPubMed

79.

Xanthakos SA. Nutritional deficiencies in obesity and after bariatric surgery. Pediatr Clin N Am. 2009;56(5):1105–21. https://doi.org/10.1016/j.pcl.2009.07.002.CrossRef

80.

de Luis DA, Pacheco D, Izaola O, et al. Clinical results and nutritional consequences of biliopancreatic diversion: three years of follow-up. Ann Nutr Metab. 2008;53(3–4):234–9. Epub 2008/12/16. https://doi.org/10.1159/000185641.CrossRefPubMed

81.

Mallory GN, Macgregor AM. Folate status following gastric bypass surgery (the great Folate mystery). Obes Surg. 1991;1(1):69–72. https://doi.org/10.1381/096089291765561493.CrossRefPubMed

82.

Toh SY, Zarshenas N, Jorgensen J. Prevalence of nutrient deficiencies in bariatric patients. Nutrition. 2009;25(11–12):1150–6. Epub 2009/05/31. https://doi.org/10.1016/j.nut.2009.03.012.CrossRefPubMed

83.

Bal BS, Finelli FC, Shope TR, et al. Nutritional deficiencies after bariatric surgery. Nat Rev Endocrinol. 2012;8(9):544–56. Epub 2012/04/24. https://doi.org/10.1038/nrendo.2012.48.CrossRefPubMed

84.

Gudzune KA, Huizinga MM, Chang HY, et al. Screening and diagnosis of micronutrient deficiencies before and after bariatric surgery. Obes Surg. 2013;23(10):1581–9. https://doi.org/10.1007/s11695-013-0919-x.CrossRefPubMedPubMedCentral

85.

Wilcken B, Bamforth F, Li Z, et al. Geographical and ethnic variation of the 677C>T allele of 5,10 methylenetetrahydrofolate reductase (MTHFR): findings from over 7000 newborns from 16 areas world wide. J Med Genet. 2003;40(8):619–25. https://doi.org/10.1136/jmg.40.8.619.CrossRefPubMedPubMedCentral

86.

Hiraoka M, Kagawa Y. Genetic polymorphisms and folate status. Congenit Anom (Kyoto). 2017;57(5):142–9. Epub 2017/07/20. https://doi.org/10.1111/cga.12232.CrossRef

87.

Steluti J, Carvalho AM, Carioca AAF, et al. Genetic variants involved in one-carbon metabolism: polymorphism frequencies and differences in homocysteine concentrations in the folic acid fortification era. Nutrients. 2017;9(6) Epub 2017/05/25 https://doi.org/10.3390/nu9060539.

88.

Schneider JA, Rees DC, Liu YT, et al. Worldwide distribution of a common methylenetetrahydrofolate reductase mutation. Am J Hum Genet. 1998;62(5):1258–60. https://doi.org/10.1086/301836.CrossRefPubMedPubMedCentral

89.

Botto LD, Yang Q. 5,10-Methylenetetrahydrofolate reductase gene variants and congenital anomalies: a HuGE review. Am J Epidemiol. 2000;151(9):862–77. https://doi.org/10.1093/oxfordjournals.aje.a010290.CrossRefPubMed

90.

Guerrini I, Thomson AD, Cook CC, et al. Direct genomic PCR sequencing of the high affinity thiamine transporter (SLC19A2) gene identifies three genetic variants in Wernicke Korsakoff syndrome (WKS). Am J Med Genet B Neuropsychiatr Genet. 2005;137B(1):17–9. https://doi.org/10.1002/ajmg.b.30194.CrossRefPubMed

91.

Zhao R, Goldman ID. Folate and thiamine transporters mediated by facilitative carriers (SLC19A1–3 and SLC46A1) and folate receptors. Mol Asp Med. 2013;34(2–3):373–85. https://doi.org/10.1016/j.mam.2012.07.006.CrossRef

92.

Frank RA, Leeper FJ, Luisi BF. Structure, mechanism and catalytic duality of thiamine-dependent enzymes. Cell Mol Life Sci. 2007;64(7–8):892–905. https://doi.org/10.1007/s00018-007-6423-5.CrossRefPubMed

93.

Eshak ES, Arafa AE. Thiamine deficiency and cardiovascular disorders. Nutr Metab Cardiovasc Dis. 2018;28(10):965–72. Epub 2018/06/22. https://doi.org/10.1016/j.numecd.2018.06.013.CrossRefPubMed

94.

Carrodeguas L, Kaidar-Person O, Szomstein S, et al. Preoperative thiamine deficiency in obese population undergoing laparoscopic bariatric surgery. Surg Obes Relat Dis. 2005;1(6):517–22; discussion 22. Epub 2005/09/28 https://doi.org/10.1016/j.soard.2005.08.003.

95.

Costello E, Kerns J. Thiamine deficiency in people with obesity. Current Developments in Nutrition. June 2019;3(Supplement_1):P18–060–19.

96.

Arora S, Lidor A, Abularrage CJ, et al. Thiamine (vitamin B1) improves endothelium-dependent vasodilatation in the presence of hyperglycemia. Ann Vasc Surg. 2006;20(5):653–8. Epub 2006/05/31. https://doi.org/10.1007/s10016-006-9055-6.CrossRefPubMed

97.

Tanaka T, Sohmiya K, Kono T, et al. Thiamine attenuates the hypertension and metabolic abnormalities in CD36-defective SHR: uncoupling of glucose oxidation from cellular entry accompanied with enhanced protein O-GlcNAcylation in CD36 deficiency. Mol Cell Biochem. 2007;299(1–2):23–35. https://doi.org/10.1007/s11010-005-9032-3.CrossRefPubMed

98.

Alaei-Shahmiri F, Soares MJ, Zhao Y, et al. The impact of thiamine supplementation on blood pressure, serum lipids and C-reactive protein in individuals with hyperglycemia: a randomised, double-blind cross-over trial. Diabetes Metab Syndr. 2015;9(4):213–7. Epub 2015/04/29. https://doi.org/10.1016/j.dsx.2015.04.014.CrossRefPubMed

99.

Zang XL, Han WQ, Yang FP, Ji KD, Wang JG, Gao PJ, et al. Association of a SNP in SLC35F3 gene with the risk of hypertension in a Chinese Han population. Front Genet. 2016;7:108. Epub 2016/06/20. doi: https://doi.org/10.3389/fgene.2016.00108.

100.

Ortigoza-Escobar JD, Molero-Luis M, Arias A, et al. Treatment of genetic defects of thiamine transport and metabolism. Expert Rev Neurother. 2016;16(7):755–63. Epub 2016/05/23. https://doi.org/10.1080/14737175.2016.1187562.CrossRefPubMed

101.

Marcé-Grau A, Martí-Sánchez L, Baide-Mairena H, et al. Genetic defects of thiamine transport and metabolism: a review of clinical phenotypes, genetics, and functional studies. J Inherit Metab Dis. 2019;42(4):581–97. Epub 2019/06/24. https://doi.org/10.1002/jimd.12125.CrossRefPubMed

102.

Troadec MB, Loréal O, Brissot P. The interaction of iron and the genome: for better and for worse. Mutat Res. 2017;774:25–32. Epub 2017/09/14. https://doi.org/10.1016/j.mrrev.2017.09.002.CrossRefPubMed

103.

Aigner E, Feldman A, Datz C. Obesity as an emerging risk factor for iron deficiency. Nutrients. 2014;6(9):3587–600. Epub 2014/09/11. https://doi.org/10.3390/nu6093587.CrossRefPubMedPubMedCentral

104.

Dopsaj V, Topić A, Savković M, et al. Associations of Common Variants in. Dis Markers. 2019;2019:4864370. Epub 2019/03/07. https://doi.org/10.1155/2019/4864370.CrossRefPubMedPubMedCentral

105.

Sonnweber T, Ress C, Nairz M, et al. High-fat diet causes iron deficiency via hepcidin-independent reduction of duodenal iron absorption. J Nutr Biochem. 2012;23(12):1600–8. Epub 2012/03/23. https://doi.org/10.1016/j.jnutbio.2011.10.013.CrossRefPubMed

106.

Micozzi MS, Albanes D, Stevens RG. Relation of body size and composition to clinical biochemical and hematologic indices in US men and women. Am J Clin Nutr. 1989;50(6):1276–81. https://doi.org/10.1093/ajcn/50.6.1276.CrossRefPubMed

107.

Cepeda-Lopez AC, Osendarp SJ, Melse-Boonstra A, et al. Sharply higher rates of iron deficiency in obese Mexican women and children are predicted by obesity-related inflammation rather than by differences in dietary iron intake. Am J Clin Nutr. 2011;93(5):975–83. Epub 2011/03/16. https://doi.org/10.3945/ajcn.110.005439.CrossRefPubMed

108.

Tussing-Humphreys LM, Nemeth E, Fantuzzi G, et al. Elevated systemic hepcidin and iron depletion in obese premenopausal females. Obesity (Silver Spring). 2010;18(7):1449–56. Epub 2009/10/08. https://doi.org/10.1038/oby.2009.319.CrossRef

109.

Malek M, Yousefi R, Safari S, et al. Dietary intakes and biochemical parameters of morbidly obese patients prior to bariatric surgery. Obes Surg. 2019;29(6):1816–22. https://doi.org/10.1007/s11695-019-03759-x.CrossRefPubMed

110.

Harju E. Empty iron stores as a significant risk factor in abdominal surgery. JPEN J Parenter Enteral Nutr. 1988;12(3):282–5. https://doi.org/10.1177/0148607188012003282.CrossRefPubMed

111.

Ruz M, Carrasco F, Rojas P, et al. Heme- and nonheme-iron absorption and iron status 12 mo after sleeve gastrectomy and Roux-en-Y gastric bypass in morbidly obese women. Am J Clin Nutr. 2012;96(4):810–7. Epub 2012/09/05. https://doi.org/10.3945/ajcn.112.039255.CrossRefPubMed

112.

McLaren CE, McLachlan S, Garner CP, et al. Associations between single nucleotide polymorphisms in iron-related genes and iron status in multiethnic populations. PLoS One. 2012;7(6):e38339. https://doi.org/10.1371/journal.pone.0038339.CrossRefPubMedPubMedCentral

113.

Lee PL, Barton JC, Khaw PL, et al. Common TMPRSS6 mutations and iron, erythrocyte, and pica phenotypes in 48 women with iron deficiency or depletion. Blood Cells Mol Dis. 2012;48(2):124–7. https://doi.org/10.1016/j.bcmd.2011.12.003.CrossRefPubMedPubMedCentral

114.

De Falco L, Tortora R, Imperatore N, et al. The role of TMPRSS6 and HFE variants in iron deficiency anemia in celiac disease. Am J Hematol. 2018;93(3):383–93. Epub 2017/12/18. https://doi.org/10.1002/ajh.24991.CrossRefPubMed

115.

Poggiali E, Andreozzi F, Nava I, et al. The role of TMPRSS6 polymorphisms in iron deficiency anemia partially responsive to oral iron treatment. Am J Hematol. 2015;90(4):306–9. Epub 2015/03/02. https://doi.org/10.1002/ajh.23929.CrossRefPubMed

116.

Tahir S, Leijssen LG, Sherif M, et al. A novel homozygous SLC19A2 mutation in a Portuguese patient with diabetes mellitus and thiamine-responsive megaloblastic anaemia. Int J Pediatr Endocrinol. 2015;2015(1):6. https://doi.org/10.1186/s13633-015-0002-6.CrossRefPubMedPubMedCentral

117.

Fassone E, Wedatilake Y, DeVile CJ, et al. Treatable Leigh-like encephalopathy presenting in adolescence. BMJ Case Rep. 2013;2013:200838. https://doi.org/10.1136/bcr-2013-200838.CrossRefPubMed

118.

Banka S, de Goede C, Yue WW, et al. Expanding the clinical and molecular spectrum of thiamine pyrophosphokinase deficiency: a treatable neurological disorder caused by TPK1 mutations. Mol Genet Metab. 2014;113(4):301–6. Epub 2014/10/05. https://doi.org/10.1016/j.ymgme.2014.09.010.CrossRefPubMed

119.

Al-Daghri NM, Mohammed AK, Bukhari I, et al. Efficacy of vitamin D supplementation according to vitamin D-binding protein polymorphisms. Nutrition. 2019;63–64:148–54. https://doi.org/10.1016/j.nut.2019.02.003.CrossRefPubMed

120.

Qin X, Li J, Cui Y, et al. MTHFR C677T and MTR A2756G polymorphisms and the homocysteine lowering efficacy of different doses of folic acid in hypertensive Chinese adults. Nutr J. 2012;11(2) https://doi.org/10.1186/1475-2891-11-2.

121.

Ashfield-Watt PA, Pullin CH, Whiting JM, et al. Methylenetetrahydrofolate reductase 677C-->T genotype modulates homocysteine responses to a folate-rich diet or a low-dose folic acid supplement: a randomized controlled trial. Am J Clin Nutr. 2002;76(1):180–6. https://doi.org/10.1093/ajcn/76.1.180.CrossRefPubMed

122.

Lea R, Colson N, Quinlan S, et al. The effects of vitamin supplementation and MTHFR (C677T) genotype on homocysteine-lowering and migraine disability. Pharmacogenet Genomics. 2009;19(6):422–8. https://doi.org/10.1097/FPC.0b013e32832af5a3.CrossRefPubMed

123.

Athiyarath R, Shaktivel K, Abraham V, et al. Association of genetic variants with response to iron supplements in pregnancy. Genes Nutr. 2015;10(4):474. https://doi.org/10.1007/s12263-015-0474-2.CrossRefPubMed

124.

Capra AP, Ferro E, Cannavò L, et al. A child with severe iron-deficiency anemia and a complex TMPRSS6 genotype. Hematology. 2017;22(9):559–64. https://doi.org/10.1080/10245332.2017.1317990.CrossRefPubMed

125.

Donkin I, Versteyhe S, Ingerslev LR, et al. Obesity and bariatric surgery drive epigenetic variation of spermatozoa in humans. Cell Metab. 2016;23(2):369–78. Epub 2015/12/06. https://doi.org/10.1016/j.cmet.2015.11.004.CrossRefPubMed

126.

Barres R, Kirchner H, Rasmussen M, et al. Weight loss after gastric bypass surgery in human obesity remodels promoter methylation. Cell Rep. 2013;3(4):1020–7. Epub 2013/04/11. https://doi.org/10.1016/j.celrep.2013.03.018.CrossRefPubMed

127.

Pinhel MAS, Noronha NY, Nicoletti CF, et al. Changes in global transcriptional profiling of women following obesity surgery bypass. Obes Surg. 2018;28(1):176–86. https://doi.org/10.1007/s11695-017-2828-x.CrossRefPubMed

128.

Sala P, Belarmino G, Torrinhas RS, et al. Gastrointestinal transcriptomic response of metabolic vitamin B12 pathways in Roux-en-Y gastric bypass. Clin Transl Gastroenterol. 2017;8(1):e212. https://doi.org/10.1038/ctg.2016.67.CrossRefPubMedPubMedCentral

129.

Nicoletti CF, Cortes-Oliveira C, Pinhel MAS, Nonino CB. Bariatric surgery and precision nutrition. Nutrients. 2017;9(9). Epub 2017/09/06. doi: https://doi.org/10.3390/nu9090974.

130.

Leyvraz C, Verdumo C, Suter M, et al. Changes in gene expression profile in human subcutaneous adipose tissue during significant weight loss. Obes Facts. 2012;5(3):440–51. Epub 2012/06/30. https://doi.org/10.1159/000341137.CrossRefPubMed

131.

Bandstein M, Schultes B, Ernst B, et al. The role of FTO and vitamin D for the weight loss effect of Roux-en-Y gastric bypass surgery in obese patients. Obes Surg. 2015;25(11):2071–7. https://doi.org/10.1007/s11695-015-1644-4.CrossRefPubMedPubMedCentral

132.

Guest NS, Horne J, Vanderhout SM, et al. Sport nutrigenomics: personalized nutrition for athletic performance. Front Nutr. 2019;6:8. https://doi.org/10.3389/fnut.2019.00008.CrossRefPubMedPubMedCentral

133.

Hesketh J, Méplan C. Transcriptomics and functional genetic polymorphisms as biomarkers of micronutrient function: focus on selenium as an exemplar. Proc Nutr Soc. 2011;70:1–9. Epub 2011/05/03. https://doi.org/10.1017/S0029665111000115.CrossRef

134.

Paul B, Barnes S, Demark-Wahnefried W, et al. Influences of diet and the gut microbiome on epigenetic modulation in cancer and other diseases. Clin Epigenetics. 2015;7:112. https://doi.org/10.1186/s13148-015-0144-7.CrossRefPubMedPubMedCentral

135.

Nicholson JK, Holmes E, Kinross J, et al. Host-gut microbiota metabolic interactions. Science. 2012;336(6086):1262–7. Epub 2012/06/06. https://doi.org/10.1126/science.1223813.CrossRefPubMed

136.

Lozupone CA, Stombaugh JI, Gordon JI, et al. Diversity, stability and resilience of the human gut microbiota. Nature. 2012;489(7415):220–30. https://doi.org/10.1038/nature11550.CrossRefPubMedPubMedCentral

137.

Das P, Babaei P, Nielsen J. Metagenomic analysis of microbe-mediated vitamin metabolism in the human gut microbiome. BMC Genomics. 2019;20(1):208. https://doi.org/10.1186/s12864-019-5591-7.CrossRefPubMedPubMedCentral

138.

Holmes E, Kinross J, Gibson GR, et al. Therapeutic modulation of microbiota-host metabolic interactions. Sci Transl Med. 2012;4(137):137rv6. https://doi.org/10.1126/scitranslmed.3004244.CrossRefPubMed

139.

van Nimwegen KJ, van Soest RA, Veltman JA, et al. Is the $1000 genome as near as we think? A cost analysis of next-generation sequencing. Clin Chem. 2016;62(11):1458–64. Epub 2016/09/14. https://doi.org/10.1373/clinchem.2016.258632.CrossRefPubMed

140.

Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Stephens K, et al. GeneReviews. 1993.

141.

Marino P, Touzani R, Perrier L, et al. Cost of cancer diagnosis using next-generation sequencing targeted gene panels in routine practice: a nationwide French study. Eur J Hum Genet. 2018;26(3):314–23. https://doi.org/10.1038/s41431-017-0081-3.CrossRefPubMedPubMedCentral

142.

Institute NNHGR. The cost of sequencing a human genome 2019.

143.

Vlahovich N, Hughes DC, Griffiths LR, et al. Genetic testing for exercise prescription and injury prevention: AIS-Athlome consortium-FIMS joint statement. BMC Genomics. 2017;18(Suppl 8):818. https://doi.org/10.1186/s12864-017-4185-5.CrossRefPubMedPubMedCentral

144.

Annas GJ, Elias S. 23andMe and the FDA. N Engl J Med. 2014;370(11):985–8. Epub 2014/02/12. https://doi.org/10.1056/NEJMp1316367.CrossRefPubMed

145.

Green ED, Guyer MS, Institute NHGR. Charting a course for genomic medicine from base pairs to bedside. Nature. 2011;470(7333):204–213. doi: https://doi.org/10.1038/nature09764,.

146.

O'Donovan CB, Walsh MC, Gibney MJ, et al. Knowing your genes: does this impact behaviour change? Proc Nutr Soc. 2017;76(3):182–91. Epub 2017/01/20. https://doi.org/10.1017/S0029665116002949.CrossRefPubMed

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Personalized Nutrition for Management of Micronutrient Deficiency—Literature Review in Non-bariatric Populations and Possible Utility in Bariatric Cohort

Abstract

Background

Methods

Results

Conclusion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

Please log in to get access to this content

Other articles of this Issue 9/2020

Bariatric Surgical Practice During the Initial Phase of COVID-19 Outbreak

Effect of Weight Loss Surgery on Biomarkers of Angiogenesis in Obese Patients

Late Gastropleural Fistula after the Management of Laparoscopic Sleeve Gastrectomy Leakage

Malpractice Claims in Bariatric Surgery in Spain

Correction to: Clinical Practice Guidelines for Childbearing Female Candidates for Bariatric Surgery, Pregnancy, and Post-Partum Management after Bariatric Surgery

Reply to: COVID-19 Digestive Symptoms Mimicking Internal Hernia Presentation After Roux-en-Y Gastric Bypass; Comment on “Internal Hernia in the Times of COVID-19: to Laparoscope or Not to Laparoscope?”