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Obesity Surgery
Published in: Obesity Surgery 11/2018

01-11-2018 | Original Contributions

Metabolic Parameters, Weight Loss, and Comorbidities 4 Years After Roux-en-Y Gastric Bypass and Sleeve Gastrectomy

Authors: Corey J. Lager, Nazanene H. Esfandiari, Yingying Luo, Angela R. Subauste, Andrew T. Kraftson, Morton B. Brown, Oliver A. Varban, Rasimcan Meral, Ruth B. Cassidy, Catherine K. Nay, Amy L. Lockwood, Darlene Bellers, Colleen M. Buda, Elif A. Oral

Published in: Obesity Surgery | Issue 11/2018

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Abstract

Background

Sleeve gastrectomy (LSG) is now the predominant bariatric surgery performed, yet there is limited long-term data comparing important outcomes between LSG and Roux-en-Y gastric bypass (RYGB). This study compares weight loss and impact on comorbidities of the two procedures.

Methods

We retrospectively evaluated weight, blood pressure, hemoglobin A1c, cholesterol, and medication use for hypertension, diabetes, and hyperlipidemia at 1–4 years post-operatively in 380 patients who underwent RYGB and 334 patients who underwent LSG at the University of Michigan from January 2008 to November 2013. Follow-up rates from 714 patients initially were 657 (92%), 556 (78%), 507 (71%), and 498 (70%) at 1–4 years post-operatively.

Results

Baseline characteristics were similar except for higher weight and BMI in LSG. There was greater weight loss with RYGB vs. LSG at all points. Hemoglobin A1c and total cholesterol improved more in RYGB vs. LSG at 4 years. There was greater remission of hypertension and discontinuation of all medications for hypertension and diabetes with RYGB at 4 years.

Conclusions

Weight loss, reduction in medications for hypertension and diabetes, improvements in markers of diabetes and hyperlipidemia, and remission rates of hypertension were superior with RYGB vs. LSG 4 years post-operatively. Choice of bariatric procedures should be tailored to surgical risk, comorbidities, and weight loss goals.
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Metadata
Title
Metabolic Parameters, Weight Loss, and Comorbidities 4 Years After Roux-en-Y Gastric Bypass and Sleeve Gastrectomy
Authors
Corey J. Lager
Nazanene H. Esfandiari
Yingying Luo
Angela R. Subauste
Andrew T. Kraftson
Morton B. Brown
Oliver A. Varban
Rasimcan Meral
Ruth B. Cassidy
Catherine K. Nay
Amy L. Lockwood
Darlene Bellers
Colleen M. Buda
Elif A. Oral
Publication date
01-11-2018
Publisher
Springer US
Published in
Obesity Surgery / Issue 11/2018
Print ISSN: 0960-8923
Electronic ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-018-3346-1

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