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Published in: Obesity Surgery 6/2017

01-06-2017 | Original Contributions

Safety Analysis of Bariatric Patients Undergoing Outpatient Upper Endoscopy with Non-Anesthesia Administered Propofol Sedation

Authors: Tyler McVay, John C. Fang, Linda Taylor, Alexander Au, Wesley Williams, Angela P. Presson, Ragheed Al-Dulaimi, Eric Volckmann, Anna Ibele

Published in: Obesity Surgery | Issue 6/2017

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Abstract

Background

Non-anesthesia administered propofol (NAAP) has been shown to be a safe and effective method of sedation for patients undergoing gastrointestinal endoscopy. Bariatric surgery patients are potentially at a higher risk for sedation-related complications due to co-morbidities including obstructive sleep apnea. The outcomes of NAAP in bariatric patients have not been previously reported.

Methods

In this retrospective cohort study, severely obese patients undergoing pre-surgical outpatient esophagogastroduodenoscopy (EGD) were compared to non-obese control patients (BMI ≤ 25 kg/m2) undergoing diagnostic EGD at our institution from March 2011–September 2015 using our endoscopy database. Patients’ demographics and procedural and recovery data, including any airway interventions, were statistically analyzed.

Results

We included 130 consecutive pre-operative bariatric surgical patients with average BMI 45.8 kg/m2 (range 34–80) and 265 control patients with average BMI 21.9 kg/m2 (range 14–25). The severely obese group had a higher prevalence of sleep apnea (62 vs 8%; p < 0.001), experienced more oxygen desaturations (22 vs 7%; p < 0.001), and received more chin lift maneuvers (20 vs 6%; p < 0.001). Advanced airway interventions were rarely required in either group and were not more frequent in the bariatric group.

Conclusions

With appropriate training of endoscopy personnel, NAAP is a safe method of sedation in severely obese patients undergoing outpatient upper endoscopy.
Literature
1.
go back to reference Berzin TM, Sanaka S, Barnett SR, et al. A prospective assessment of sedation-related adverse events and patient and endoscopist satisfaction in ERCP with anesthesiologist-administered sedation. Gastrointest Endosc. 2011;73(4):710–7. doi:10.1016/j.gie.2010.12.011.CrossRefPubMed Berzin TM, Sanaka S, Barnett SR, et al. A prospective assessment of sedation-related adverse events and patient and endoscopist satisfaction in ERCP with anesthesiologist-administered sedation. Gastrointest Endosc. 2011;73(4):710–7. doi:10.​1016/​j.​gie.​2010.​12.​011.CrossRefPubMed
4.
go back to reference White PF. Intravenous (non-opioid) anesthesia. Seminars in Anesthesia, Perioperative Medicine and Pain. 2005;24(2):101–7.CrossRef White PF. Intravenous (non-opioid) anesthesia. Seminars in Anesthesia, Perioperative Medicine and Pain. 2005;24(2):101–7.CrossRef
8.
go back to reference Sieg A, bng-Study-Group, Beck S, et al. Safety analysis of endoscopist-directed propofol sedation: a prospective, national multicenter study of 24 441 patients in German outpatient practices. J Gastroenterol Hepatol. 2014;29(3):517–23.CrossRefPubMed Sieg A, bng-Study-Group, Beck S, et al. Safety analysis of endoscopist-directed propofol sedation: a prospective, national multicenter study of 24 441 patients in German outpatient practices. J Gastroenterol Hepatol. 2014;29(3):517–23.CrossRefPubMed
9.
go back to reference Tohda G, Higashi S, Wakahara S, et al. Propofol sedation during endoscopic procedures: safe and effective administration by registered nurses supervised by endoscopists. Endoscopy. 2006;38:360–7.CrossRefPubMed Tohda G, Higashi S, Wakahara S, et al. Propofol sedation during endoscopic procedures: safe and effective administration by registered nurses supervised by endoscopists. Endoscopy. 2006;38:360–7.CrossRefPubMed
10.
go back to reference Rex DK, Overley C, Kinser K, et al. Safety of propofol administered by registered nurses with gastroenterologist supervision in 2000 endoscopic cases. Am J Gastroenterol. 2002;97(5):1159–63.CrossRefPubMed Rex DK, Overley C, Kinser K, et al. Safety of propofol administered by registered nurses with gastroenterologist supervision in 2000 endoscopic cases. Am J Gastroenterol. 2002;97(5):1159–63.CrossRefPubMed
11.
go back to reference Külling D, Rothenbühler R, Inauen W. Safety of nonanesthetist sedation with propofol for outpatient colonoscopy and esophagogastroduodenoscopy. Endoscopy. 2003;35(8):679–82.CrossRefPubMed Külling D, Rothenbühler R, Inauen W. Safety of nonanesthetist sedation with propofol for outpatient colonoscopy and esophagogastroduodenoscopy. Endoscopy. 2003;35(8):679–82.CrossRefPubMed
12.
go back to reference Sieg A. Propofol sedation in outpatient colonoscopy by trained practice nurses supervised by the gastroenterologist: a prospective evaluation of over 3000 cases. Z Gastroenterol. 2007;45(8):697–701.CrossRefPubMed Sieg A. Propofol sedation in outpatient colonoscopy by trained practice nurses supervised by the gastroenterologist: a prospective evaluation of over 3000 cases. Z Gastroenterol. 2007;45(8):697–701.CrossRefPubMed
13.
go back to reference American Society for Gastrointestinal Endoscopy, the American Association for the Study of Liver Diseases, American College of Gastroenterology, and AGA Institute. Position statement: nonanesthesiologist administration of propofol for GI endoscopy. Gastrointest Endosc. 2009;70(6). American Society for Gastrointestinal Endoscopy, the American Association for the Study of Liver Diseases, American College of Gastroenterology, and AGA Institute. Position statement: nonanesthesiologist administration of propofol for GI endoscopy. Gastrointest Endosc. 2009;70(6).
14.
go back to reference National Center for Health Statistics. Health, United States, 2014: with special feature on adults aged 55–64. Hyattsville; 2015. National Center for Health Statistics. Health, United States, 2014: with special feature on adults aged 55–64. Hyattsville; 2015.
15.
18.
go back to reference Chung F, Yegneswaran B, Liao P, et al. Validation of the Berlin questionnaire and American Society of Anesthesiologists checklist as screening tools for obstructive sleep apnea in surgical patients. Anesthesiology. 2008;108(5):822–30. doi:10.1097/ALN.0b013e31816d91b5.CrossRefPubMed Chung F, Yegneswaran B, Liao P, et al. Validation of the Berlin questionnaire and American Society of Anesthesiologists checklist as screening tools for obstructive sleep apnea in surgical patients. Anesthesiology. 2008;108(5):822–30. doi:10.​1097/​ALN.​0b013e31816d91b5​.CrossRefPubMed
20.
22.
go back to reference Mehta PP, Kochhar G, Kalra S, et al. Can a validated sleep apnea scoring system predict cardiopulmonary events using propofol sedation for routine EGD or colonoscopy? A prospective cohort study. Gastrointest Endosc. 2014;79(3):436–44. doi:10.1016/j.gie.2013.09.022.CrossRefPubMed Mehta PP, Kochhar G, Kalra S, et al. Can a validated sleep apnea scoring system predict cardiopulmonary events using propofol sedation for routine EGD or colonoscopy? A prospective cohort study. Gastrointest Endosc. 2014;79(3):436–44. doi:10.​1016/​j.​gie.​2013.​09.​022.CrossRefPubMed
23.
go back to reference Heuss LT, Schnieper P, Drewe J, et al. Safety of propofol for conscious sedation during endoscopic procedures in high-risk patients—a prospective, controlled study. Am J Gastroenterol. 2003;98(8):1751–7.PubMed Heuss LT, Schnieper P, Drewe J, et al. Safety of propofol for conscious sedation during endoscopic procedures in high-risk patients—a prospective, controlled study. Am J Gastroenterol. 2003;98(8):1751–7.PubMed
24.
go back to reference Kawa C, Stewart J, Hilden K, et al. A retrospective study of nurse-assisted propofol sedation in patients with amyotrophic lateral sclerosis undergoing percutaneous endoscopic gastrostomy. Nutr Clin Pract. 2012;27(4):540–4. doi:10.1177/0884533612443712.CrossRefPubMed Kawa C, Stewart J, Hilden K, et al. A retrospective study of nurse-assisted propofol sedation in patients with amyotrophic lateral sclerosis undergoing percutaneous endoscopic gastrostomy. Nutr Clin Pract. 2012;27(4):540–4. doi:10.​1177/​0884533612443712​.CrossRefPubMed
25.
go back to reference American Society of Anesthesiologists. Statement on safe use of propofol. Committee of Origin: ambulatory surgical care. 2004. www.asahq.org. American Society of Anesthesiologists. Statement on safe use of propofol. Committee of Origin: ambulatory surgical care. 2004. www.​asahq.​org.
26.
go back to reference American Association of Nurse Anesthetists. AANA-ASA joint position statement regarding propofol administration. Adopted April 14, 2004. www.aana.com. American Association of Nurse Anesthetists. AANA-ASA joint position statement regarding propofol administration. Adopted April 14, 2004. www.​aana.​com.
Metadata
Title
Safety Analysis of Bariatric Patients Undergoing Outpatient Upper Endoscopy with Non-Anesthesia Administered Propofol Sedation
Authors
Tyler McVay
John C. Fang
Linda Taylor
Alexander Au
Wesley Williams
Angela P. Presson
Ragheed Al-Dulaimi
Eric Volckmann
Anna Ibele
Publication date
01-06-2017
Publisher
Springer US
Published in
Obesity Surgery / Issue 6/2017
Print ISSN: 0960-8923
Electronic ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-016-2478-4

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