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Obesity Surgery
Published in: Obesity Surgery 3/2016

01-03-2016 | Review Article

Obstructive Sleep Apnea and Smoking as a Risk Factor for Venous Thromboembolism Events: Review of the Literature on the Common Pathophysiological Mechanisms

Authors: Eric Deflandre, Stephanie Degey, Natacha Opsomer, Jean-Francois Brichant, Jean Joris

Published in: Obesity Surgery | Issue 3/2016

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Abstract

Venous thromboembolism events (VTE) are a common and preventable cause of postoperative complications. Interestingly, smoking and obstructive sleep apnea syndrome (OSA) affecting a large part of our population (and especially obese patients) are two underestimated predisposing factors of VTE. Many coagulation disorders favoring thromboembolism have been identified in the case of OSA and smoking and are reviewed in this article. They can be divided into two entities: endothelial dysfunction and hemostasis disorders. Interestingly OSA and smoking share common pathways to the prothrombotic state. The interactions with others comorbidities will also be discussed. This article provides pathophysiological mechanisms of the increased risk of thromboembolism in OSA patients and smokers, which should help manage these patients more adequately during the perioperative period.
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Metadata
Title
Obstructive Sleep Apnea and Smoking as a Risk Factor for Venous Thromboembolism Events: Review of the Literature on the Common Pathophysiological Mechanisms
Authors
Eric Deflandre
Stephanie Degey
Natacha Opsomer
Jean-Francois Brichant
Jean Joris
Publication date
01-03-2016
Publisher
Springer US
Published in
Obesity Surgery / Issue 3/2016
Print ISSN: 0960-8923
Electronic ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-015-2012-0

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