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Published in: Obesity Surgery 7/2016

01-07-2016 | Original Contributions

An Integrative Therapeutic Concept for Surgical Treatment of Severe Cases of Lymphedema of the Lower Extremity

Authors: Jurij Kiefer, Georgios Koulaxouzidis, G. Björn Stark, Etelka Foeldi, Nestor Torio-Padron, Vincenzo Penna

Published in: Obesity Surgery | Issue 7/2016

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Abstract

Background

Lymphedema results from insufficient lymphatic drainage and typically affects the extremities. Recent studies revealed obesity as another cause of extremity lymphedema. Conservative treatment of patients with elephantiastic lymphedema of the lower extremity is limited and often inadequate. Resecting surgery plays an important role in these cases. Here, we investigated the effects of an integrated therapy concept on outcome and complication rates.

Methods

We retrospectively analyzed the clinical outcome of 26 patients with elephantiastic lymphedema of the lower limb who underwent a complex decongestive physical therapy (CDP) perioperatively and reduction surgery in our clinic between 1998 and 2011. We subsequently compared these patients (group A) with a control group of 30 patients (group B) who received medial thigh lift due to post-bariatric or aesthetic issues between 2011 and 2013. The incidence of complications, reoperations, blood transfusion, and duration of hospital stay was analyzed. All patients in group A received CDP perioperatively in a specialized lymphological clinic.

Results

Both groups are comparable in terms of age and sex. Patients significantly differ in terms of BMI (p < 0.001). Thirty-six reductive procedures were performed in group A and 30 in group B. We did not see any significant difference in the incidence of complications (p = 1.000) and the rate of postoperative blood transfusions (p = 0.116).

Conclusions

We were able to show that an integrative concept including surgery is a good additional option for the treatment of severe cases of lymphedema in appropriate candidates. Furthermore, an adequate perioperative conservative setting helps to minimize possible complications.
Literature
1.
go back to reference Clark B, Sitzia J, Harlow W. Incidence and risk of arm oedema following treatment for breast cancer: a three-year follow-up study. QJM: Mon J Assoc Phys. 2005;98:343–8.CrossRef Clark B, Sitzia J, Harlow W. Incidence and risk of arm oedema following treatment for breast cancer: a three-year follow-up study. QJM: Mon J Assoc Phys. 2005;98:343–8.CrossRef
2.
go back to reference Lawenda BD, Mondry TE, Johnstone PA. Lymphedema: a primer on the identification and management of a chronic condition in oncologic treatment. CA: Cancer J Clin. 2009;59:8–24. Lawenda BD, Mondry TE, Johnstone PA. Lymphedema: a primer on the identification and management of a chronic condition in oncologic treatment. CA: Cancer J Clin. 2009;59:8–24.
3.
go back to reference Greene AK, Grant FD, Slavin SA. Lower-extremity lymphedema and elevated body-mass index. N Engl J Med. 2012;366:2136–7.CrossRefPubMed Greene AK, Grant FD, Slavin SA. Lower-extremity lymphedema and elevated body-mass index. N Engl J Med. 2012;366:2136–7.CrossRefPubMed
5.
go back to reference Pyszel A, Malyszczak K, Pyszel K, et al. Disability, psychological distress and quality of life in breast cancer survivors with arm lymphedema. Lymphology. 2006;39:185–92.PubMed Pyszel A, Malyszczak K, Pyszel K, et al. Disability, psychological distress and quality of life in breast cancer survivors with arm lymphedema. Lymphology. 2006;39:185–92.PubMed
6.
go back to reference Ridner SH. Quality of life and a symptom cluster associated with breast cancer treatment-related lymphedema. Support Care Cancer: Off J Multinatl Assoc Support Care Cancer. 2005;13:904–11.CrossRef Ridner SH. Quality of life and a symptom cluster associated with breast cancer treatment-related lymphedema. Support Care Cancer: Off J Multinatl Assoc Support Care Cancer. 2005;13:904–11.CrossRef
7.
go back to reference International Society of L. The diagnosis and treatment of peripheral lymphedema: 2013 consensus document of the international society of lymphology. Lymphology. 2013;46:1–11. International Society of L. The diagnosis and treatment of peripheral lymphedema: 2013 consensus document of the international society of lymphology. Lymphology. 2013;46:1–11.
8.
go back to reference Foeldi M, Foeldi E. Földi’s Textbook of Lymphology: for Physicians and Lymphedema Therapists, 3rd edn. Urban & Fischer Verlag/Elsevier GmbH; 2012. Foeldi M, Foeldi E. Földi’s Textbook of Lymphology: for Physicians and Lymphedema Therapists, 3rd edn. Urban & Fischer Verlag/Elsevier GmbH; 2012.
9.
go back to reference Didem K, Ufuk YS, Serdar S, et al. The comparison of two different physiotherapy methods in treatment of lymphedema after breast surgery. Breast Cancer Res Treat. 2005;93:49–54.CrossRefPubMed Didem K, Ufuk YS, Serdar S, et al. The comparison of two different physiotherapy methods in treatment of lymphedema after breast surgery. Breast Cancer Res Treat. 2005;93:49–54.CrossRefPubMed
10.
go back to reference Liao SF, Huang MS, Li SH, et al. Complex decongestive physiotherapy for patients with chronic cancer-associated lymphedema. J Formos Med Assoc = Taiwan Yi Zhi. 2004;103:344–8.PubMed Liao SF, Huang MS, Li SH, et al. Complex decongestive physiotherapy for patients with chronic cancer-associated lymphedema. J Formos Med Assoc = Taiwan Yi Zhi. 2004;103:344–8.PubMed
11.
go back to reference Sato K. Complex decongestive physiotherapy (CDP). Nihon Rinsho Jpn J Clin Med. 2005;63:144–53. Sato K. Complex decongestive physiotherapy (CDP). Nihon Rinsho Jpn J Clin Med. 2005;63:144–53.
13.
go back to reference Kim SJ, Park YD. Effects of complex decongestive physiotherapy on the oedema and the quality of life of lower unilateral lymphoedema following treatment for gynecological cancer. Eur J Cancer Care. 2008;17:463–8.CrossRef Kim SJ, Park YD. Effects of complex decongestive physiotherapy on the oedema and the quality of life of lower unilateral lymphoedema following treatment for gynecological cancer. Eur J Cancer Care. 2008;17:463–8.CrossRef
14.
go back to reference Kim SJ, Yi CH, Kwon OY. Effect of complex decongestive therapy on edema and the quality of life in breast cancer patients with unilateral leymphedema. Lymphology. 2007;40:143–51.PubMed Kim SJ, Yi CH, Kwon OY. Effect of complex decongestive therapy on edema and the quality of life in breast cancer patients with unilateral leymphedema. Lymphology. 2007;40:143–51.PubMed
15.
go back to reference Gusenoff JA, Coon D, Nayar H, et al. Medial thigh lift in the massive weight loss population: outcomes and complications. Plast Reconstr Surg. 2015;135:98–106.CrossRefPubMed Gusenoff JA, Coon D, Nayar H, et al. Medial thigh lift in the massive weight loss population: outcomes and complications. Plast Reconstr Surg. 2015;135:98–106.CrossRefPubMed
16.
go back to reference Kim DI, Huh S, Lee SJ, et al. Excision of subcutaneous tissue and deep muscle fascia for advanced lymphedema. Lymphology. 1998;31:190–4.PubMed Kim DI, Huh S, Lee SJ, et al. Excision of subcutaneous tissue and deep muscle fascia for advanced lymphedema. Lymphology. 1998;31:190–4.PubMed
17.
go back to reference Brorson H. Liposuction in arm lymphedema treatment. Scand J Surg: SJS: Off Organ Finn Surg Soc Scand Surg Soc. 2003;92:287–95. Brorson H. Liposuction in arm lymphedema treatment. Scand J Surg: SJS: Off Organ Finn Surg Soc Scand Surg Soc. 2003;92:287–95.
18.
go back to reference Brorson H, Svensson H. Liposuction combined with controlled compression therapy reduces arm lymphedema more effectively than controlled compression therapy alone. Plast Reconstr Surg. 1998;102:1058–67. discussion 1068.CrossRefPubMed Brorson H, Svensson H. Liposuction combined with controlled compression therapy reduces arm lymphedema more effectively than controlled compression therapy alone. Plast Reconstr Surg. 1998;102:1058–67. discussion 1068.CrossRefPubMed
19.
go back to reference Kolker AR, Xipoleas GD. The circumferential thigh lift and vertical extension circumferential thigh lift: maximizing aesthetics and safety in lower extremity contouring. Ann Plast Surg. 2011;66:452–6.CrossRefPubMed Kolker AR, Xipoleas GD. The circumferential thigh lift and vertical extension circumferential thigh lift: maximizing aesthetics and safety in lower extremity contouring. Ann Plast Surg. 2011;66:452–6.CrossRefPubMed
20.
go back to reference Charlson ME, Pompei P, Ales KL, et al. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987;40:373–83.CrossRefPubMed Charlson ME, Pompei P, Ales KL, et al. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987;40:373–83.CrossRefPubMed
21.
go back to reference Dindo D, Demartines N, Clavien PA. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg. 2004;240:205–13.CrossRefPubMedPubMedCentral Dindo D, Demartines N, Clavien PA. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg. 2004;240:205–13.CrossRefPubMedPubMedCentral
22.
go back to reference Lerner R. Complete decongestive physiotherapy and the Lerner lymphedema services academy of lymphatic studies (the Lerner school). Cancer. 1998;83:2861–3.CrossRefPubMed Lerner R. Complete decongestive physiotherapy and the Lerner lymphedema services academy of lymphatic studies (the Lerner school). Cancer. 1998;83:2861–3.CrossRefPubMed
23.
go back to reference Shih YC, Xu Y, Cormier JN, et al. Incidence, treatment costs, and complications of lymphedema after breast cancer among women of working age: a 2-year follow-up study. J Clin Oncol: Off J Am Soc Clin Oncol. 2009;27:2007–14.CrossRef Shih YC, Xu Y, Cormier JN, et al. Incidence, treatment costs, and complications of lymphedema after breast cancer among women of working age: a 2-year follow-up study. J Clin Oncol: Off J Am Soc Clin Oncol. 2009;27:2007–14.CrossRef
24.
go back to reference Granzow JW, Soderberg JM, Kaji AH, et al. Review of current surgical treatments for lymphedema. Ann Surg Oncol. 2014;21:1195–201.CrossRefPubMed Granzow JW, Soderberg JM, Kaji AH, et al. Review of current surgical treatments for lymphedema. Ann Surg Oncol. 2014;21:1195–201.CrossRefPubMed
25.
go back to reference Brorson H, Ohlin K, Olsson G, et al. Quality of life following liposuction and conservative treatment of arm lymphedema. Lymphology. 2006;39:8–25.PubMed Brorson H, Ohlin K, Olsson G, et al. Quality of life following liposuction and conservative treatment of arm lymphedema. Lymphology. 2006;39:8–25.PubMed
26.
go back to reference Ruocco V, Schwartz RA, Ruocco E. Lymphedema: an immunologically vulnerable site for development of neoplasms. J Am Acad Dermatol. 2002;47:124–7.CrossRefPubMed Ruocco V, Schwartz RA, Ruocco E. Lymphedema: an immunologically vulnerable site for development of neoplasms. J Am Acad Dermatol. 2002;47:124–7.CrossRefPubMed
27.
go back to reference Koulaxouzidis G, Goerke SM, Eisenhardt SU, et al. An integrated therapy concept for reduction of postoperative complications after resection of a panniculus morbidus. Obes Surg. 2012;22:549–54.CrossRefPubMed Koulaxouzidis G, Goerke SM, Eisenhardt SU, et al. An integrated therapy concept for reduction of postoperative complications after resection of a panniculus morbidus. Obes Surg. 2012;22:549–54.CrossRefPubMed
28.
go back to reference Reutter F, Reuter DA, Hilgarth H, et al. Perioperative antibiotic prophylaxis. Anaesthesist. 2014;63:73–86.CrossRefPubMed Reutter F, Reuter DA, Hilgarth H, et al. Perioperative antibiotic prophylaxis. Anaesthesist. 2014;63:73–86.CrossRefPubMed
29.
30.
31.
go back to reference Arslan H, Uludag A, Kapukaya A, et al. Effect of lymphedema on the recovery of fractures. J Orthop Sci: Off J Jpn Orthop Assoc. 2007;12:578–84.CrossRef Arslan H, Uludag A, Kapukaya A, et al. Effect of lymphedema on the recovery of fractures. J Orthop Sci: Off J Jpn Orthop Assoc. 2007;12:578–84.CrossRef
32.
go back to reference Szczesny G, Olszewski WL, Gewartowska M, et al. The healing of tibial fracture and response of the local lymphatic system. J Trauma. 2007;63:849–54.CrossRefPubMed Szczesny G, Olszewski WL, Gewartowska M, et al. The healing of tibial fracture and response of the local lymphatic system. J Trauma. 2007;63:849–54.CrossRefPubMed
Metadata
Title
An Integrative Therapeutic Concept for Surgical Treatment of Severe Cases of Lymphedema of the Lower Extremity
Authors
Jurij Kiefer
Georgios Koulaxouzidis
G. Björn Stark
Etelka Foeldi
Nestor Torio-Padron
Vincenzo Penna
Publication date
01-07-2016
Publisher
Springer US
Published in
Obesity Surgery / Issue 7/2016
Print ISSN: 0960-8923
Electronic ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-015-1982-2

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