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Obesity Surgery
Published in: Obesity Surgery 5/2016

01-05-2016 | Original Contributions

The Effect of Bariatric Surgery Type on Lipid Profile: An Age, Sex, Body Mass Index and Excess Weight Loss Matched Study

Authors: Filipe M. Cunha, Joana Oliveira, John Preto, Ana Saavedra, Maria M. Costa, Daniela Magalhães, Eva Lau, Rita Bettencourt-Silva, Paula Freitas, Ana Varela, Davide Carvalho

Published in: Obesity Surgery | Issue 5/2016

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Abstract

Background

Bariatric surgery improves lipid profile. A still unanswered question is whether this improvement is merely weight-dependent or also results from factors inherent to specificities of the bariatric procedure. We aimed to study lipid profile 1 year after bariatric surgery and compare its changes between the different procedures in patients matched for initial weight and weight loss.

Methods

We retrospectively analysed patients submitted to Roux-en-Y gastric bypass (RYGB), adjustable gastric banding (AGB) or sleeve gastrectomy (SG) between 2010 and 2013. Patients were matched for age (±5 years), sex, pre-surgery body mass index (BMI) (±2 Kg/m2) and excess weight loss (EWL) (±5 %). Baseline and 1-year lipid profile, its variation and percentage of variation was compared between surgeries.

Results

We analysed 229 patients: 72 pairs RYGB-AGB, 47 pairs RYGB-SG and 33 pairs AGB-SG. The median age was 41 (35–52) years and 11.8 % were male. Pre-operative BMI was 44.0 ± 4.6 and 32.1 ± 4.4 Kg/m2 at 1 year. EWL at 1 year was 64.2 ± 18.9 %. There were no differences in baseline lipid profile between patients submitted to different types of bariatric surgery. At 1 year, high-density lipoprotein cholesterol (HDL) and triglycerides (TG) improved similarly with all surgeries. Total cholesterol (TC) and low-density lipoprotein cholesterol (LDL) at 1 year decreased significantly more in patients submitted to RYGB than in weight-matched patients undergoing AGB or SG.

Conclusions

RYGB is the only bariatric surgery that reduces TC and LDL in age-, sex-, BMI- and EWL-matched patients. All three procedures improved TG and HDL similarly when the confounding effect of weight loss is eliminated.
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Metadata
Title
The Effect of Bariatric Surgery Type on Lipid Profile: An Age, Sex, Body Mass Index and Excess Weight Loss Matched Study
Authors
Filipe M. Cunha
Joana Oliveira
John Preto
Ana Saavedra
Maria M. Costa
Daniela Magalhães
Eva Lau
Rita Bettencourt-Silva
Paula Freitas
Ana Varela
Davide Carvalho
Publication date
01-05-2016
Publisher
Springer US
Published in
Obesity Surgery / Issue 5/2016
Print ISSN: 0960-8923
Electronic ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-015-1825-1

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