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Obesity Surgery

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01-01-2016 | Original Contributions

Influence of Roux-en-Y Gastric Bypass on the Nutritional Status of Vitamin A in Pregnant Women: a Comparative Study

Authors: Suzana N. Machado, Silvia Pereira, Carlos Saboya, Cláudia Saunders, Andréa Ramalho

Published in: Obesity Surgery | Issue 1/2016

Abstract

Objective

The objective of the present study is to evaluate the nutritional status of vitamin A through biochemical and functional indicators of pregnant women who underwent Roux-en-Y gastric bypass (RYGB) surgery compared to pregnant women who did not undergo this surgery.

Methods

The present study is a cross-sectional study of the analytical type with pregnant women paired by age and prepregnancy body mass index (BMI). Group 1 (G1) comprised 80 pregnant women without previous submission to RYGB and group 2 (G2) by 40 pregnant women who previously underwent this surgery. We used high-performance liquid chromatography with UV detector for quantification of retinol and β-carotene, and the functional evaluation of vitamin A deficiency (VAD) was performed through standardized interview validated for pregnant women.

Results

G1 mean age was 29.3 ± 5.3 and 30.8 ± 4.4 in G2. BMI mean prepregnancy found in G1 was 25.7 ± 3.2 and 26.8 ± 3.1 in G2, featuring overweight. Serum retinol and β-carotene means were significantly higher in G1 (1.8 ± 0.9; 87.4 ± 62.2) compared to G2 (0.99 ± 0.39; 22.7 ± 18.0), respectively (p < 0.001). Regarding the functional indicator for evaluation of VAD, approximately 75.0 % of pregnant women in G2 showed night blindness and 20.0 % in G1, and the percentage of pregnant women with this functional impairment was significantly higher in G2 compared to G1 with p < 0.001.

Conclusion

Results show that pregnancy after RYGB can represent a high-risk situation for VAD. We recommend interdisciplinary monitoring added to the prenatal routine consultations and the conduction of studies addressed to the investigation of a safe and effective dose of oral supplementation of vitamin A to pregnant women undergoing RYGB.

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Title: Influence of Roux-en-Y Gastric Bypass on the Nutritional Status of Vitamin A in Pregnant Women: a Comparative Study
Authors: Suzana N. Machado
Silvia Pereira
Carlos Saboya
Cláudia Saunders
Andréa Ramalho
Publication date: 01-01-2016
Publisher: Springer US
Published in: Obesity Surgery / Issue 1/2016
Print ISSN: 0960-8923
Electronic ISSN: 1708-0428
DOI: https://doi.org/10.1007/s11695-015-1734-3

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Influence of Roux-en-Y Gastric Bypass on the Nutritional Status of Vitamin A in Pregnant Women: a Comparative Study

Abstract

Objective

Methods

Results

Conclusion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Objective

Methods

Results

Conclusion

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