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Open Access 01-05-2015 | Review Article

Bariatric Surgery in Morbidly Obese Adolescents: a Systematic Review and Meta-analysis

Authors: Givan F. Paulus, Loes E. G. de Vaan, Froukje J. Verdam, Nicole D. Bouvy, Ton A. W. Ambergen, L. W. Ernest van Heurn

Published in: Obesity Surgery | Issue 5/2015

Abstract

Pubmed, Embase, and Cochrane were systematically reviewed for available evidence on bariatric surgery in adolescents. Thirty-seven included studies evaluated the effect of laparoscopic adjustable gastric banding (LAGB), Roux-en-Y gastric bypass (RYGB), or laparoscopic sleeve gastrectomy (LSG) in patients ≤18 years old. Fifteen of 37 studies were prospective, including one RCT. Mean body mass index (BMI) loss after LAGB was 11.6 kg/m² (95 % CI 9.8–13.4), versus 16.6 kg/m² (95 % CI 13.4–19.8) after RYGB and 14.1 kg/m² (95 % CI 10.8–17.5) after LSG. Two unrelated deaths were reported after 495 RYGB procedures. All three bariatric procedures result in substantial weight loss and improvement of comorbidity with an acceptable complication rate, indicating that surgical intervention is applicable in appropriately selected morbidly obese adolescents.

Obesity: preventing and managing the global epidemic. Report of a WHO consultation. World Health Organ Tech Rep Ser. 2000;894:i-xii, 1-253. PubMed PMID: 11234459.

Ogden CL, Flegal KM, Carroll MD, et al. Prevalence and trends in overweight among US children and adolescents, 1999-2000. JAMA. 2002;288(14):1728–32. PubMed PMID: 12365956.CrossRefPubMed

Ogden CL, Carroll MD, Kit BK, et al. Prevalence of obesity and trends in body mass index among US children and adolescents, 1999-2010. JAMA. 2012;307(5):483–90. PubMed PMID: 22253364.CrossRefPubMed

Rocchini AP. Childhood obesity and coronary heart disease. N Engl J Med. 2011;365(20):1927–9. PubMed PMID: 22087684.CrossRefPubMed

Juonala M, Magnussen CG, Berenson GS, et al. Childhood adiposity, adult adiposity, and cardiovascular risk factors. N Engl J Med. 2011;365(20):1876–85. PubMed PMID: 22087679.CrossRefPubMed

Russell-Mayhew S, McVey G, Bardick A, et al. Mental health, wellness, and childhood overweight/obesity. J Obes. 2012;2012:281801. PubMed PMID: 22778915. Pubmed Central PMCID: 3388583.CrossRefPubMedCentralPubMed

Abdullah A, Wolfe R, Stoelwinder JU, et al. The number of years lived with obesity and the risk of all-cause and cause-specific mortality. Int J Epidemiol. 2011;40(4):985–96. PubMed PMID: 21357186.CrossRefPubMed

Oude Luttikhuis H, Baur L, Jansen H, et al. Interventions for treating obesity in children. Cochrane Database Syst Rev (Online). 2009 (1):CD001872. PubMed PMID: 19160202.

Sjöström L. Review of the key results from the Swedish Obese Subjects (SOS) trial - a prospective controlled intervention study of bariatric surgery. J Intern Med. 2013;273(3):219–34.CrossRefPubMed

10.

International Pediatric Endosurgery G. IPEG guidelines for surgical treatment of extremely obese adolescents. J Laparoendosc Adv Surg Tech A. 2009;19 Suppl 1.

11.

Treadwell JR, Sun F, Schoelles K. Systematic review and meta-analysis of bariatric surgery for pediatric obesity. Ann Surg. 2008;248(5):763–76. PubMed PMID: 18948803.CrossRefPubMed

12.

Moher D, Liberati A, Tetzlaff J, et al. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med. 2009;6(7):e1000097. PubMed PMID: 19621072. Pubmed Central PMCID: PMC2707599.CrossRefPubMedCentralPubMed

13.

Stroup DF, Berlin JA, Morton SC, et al. Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group. JAMA. 2000;283(15):2008–12. PubMed PMID: 10789670.CrossRefPubMed

14.

Holterman AX, Browne A, Tussing L, et al. A prospective trial for laparoscopic adjustable gastric banding in morbidly obese adolescents: an interim report of weight loss, metabolic and quality of life outcomes. J Pediatr Surg. 2010;45(1):74–8. discussion 8–9. PubMed PMID: 20105583.CrossRefPubMed

15.

O’Brien PE, Sawyer SM, Laurie C, et al. Laparoscopic adjustable gastric banding in severely obese adolescents: a randomized trial. JAMA. 2010;303(6):519–26. PubMed PMID: 20145228.CrossRefPubMed

16.

Silberhumer GR, Miller K, Kriwanek S, et al. Laparoscopic adjustable gastric banding in adolescents: the Austrian experience. Obes Surg. 2006;16(8):1062–7. PubMed PMID: 16901361.CrossRefPubMed

17.

Silberhumer GR, Miller K, Pump A, et al. Long-term results after laparoscopic adjustable gastric banding in adolescent patients: follow-up of the Austrian experience. Surg Endosc. 2011;25(9):2993–9. PubMed PMID: 21573716.CrossRefPubMed

18.

Yitzhak A, Mizrahi S, Avinoach E. Laparoscopic gastric banding in adolescents. Obes Surg. 2006;16(10):1318–22. PubMed PMID: 17059740.CrossRefPubMed

19.

Sugerman HJ, Sugerman EL, DeMaria EJ, et al. Bariatric surgery for severely obese adolescents. J Gastrointest Surg. 2003;7(1):102.CrossRefPubMed

20.

Zeller MH, Modi AC, Noll JG, et al. Psychosocial functioning improves following adolescent bariatric surgery. Obesity (Silver Spring). 2009;17(5):985–90. PubMed PMID: 19165158.CrossRef

21.

Zeller MH, Reiter-Purtill J, Ratcliff MB, et al. Two-year trends in psychosocial functioning after adolescent Roux-en-Y gastric bypass. Surg Obes Relat Dis. 2011;7(6):727–32. PubMed PMID: 21497142.CrossRefPubMed

22.

Olbers T, Gronowitz E, Werling M, et al. Two-year outcome of laparoscopic Roux-en-Y gastric bypass in adolescents with severe obesity: results from a Swedish Nationwide Study (AMOS). Int J Obes (2005). 2012;36(11):1388–95. PubMed PMID: 23007037.CrossRef

23.

Aldaqal S, Sehlo M. Self-esteem and quality of life in adolescents with extreme obesity in Saudi Arabia: the effect of weight loss after laparoscopic sleeve gastrectomy. Gen Hosp Psychiatry. 2013;35(3):259–64.CrossRefPubMed

24.

O’Brien PE, Dixon JB, Laurie C, et al. A prospective randomized trial of placement of the laparoscopic adjustable gastric band: comparison of the perigastric and pars flaccida pathways. Obes Surg. 2005;15(6):820–6. PubMed PMID: 15978154.CrossRefPubMed

25.

Montero PN, Stefanidis D, Norton HJ, et al. Reported excess weight loss after bariatric surgery could vary significantly depending on calculation method: a plea for standardization. Surg Obes Relat Dis. 2011;7(4):531–4.CrossRefPubMed

26.

Belle SH, Berk PD, Courcoulas AP, et al. Reporting weight change: standardized reporting accounting for baseline weight. Surg Obes Relat Dis. 2013;9(5):782–9.CrossRefPubMedCentralPubMed

27.

Abu-Abeid S, Gavert N, Klausner JM, et al. Bariatric surgery in adolescence. J Pediatr Surg. 2003;38(9):1379–82. PubMed PMID: 14523824.CrossRefPubMed

28.

Al-Qahtani AR. Laparoscopic adjustable gastric banding in adolescent: safety and efficacy. J Pediatr Surg. 2007;42(5):894–7. PubMed PMID: 17502207.CrossRefPubMed

29.

Alqahtani A. Robotic gastric banding in children and adolescents: a comparative study. Surg Endosc. 2011;25(11):3647–51. PubMed PMID: 21638172.CrossRefPubMed

30.

Angrisani L, Favretti F, Furbetta F, et al. Obese teenagers treated by Lap-Band System: the Italian experience. Surgery. 2005;138(5):877–81. PubMed PMID: 16291388.CrossRefPubMed

31.

Dolan K, Creighton L, Hopkins G, et al. Laparoscopic gastric banding in morbidly obese adolescents. Obes Surg. 2003;13(1):101–4. PubMed PMID: 12630622.CrossRefPubMed

32.

Fielding GA, Duncombe JE. Laparoscopic adjustable gastric banding in severely obese adolescents. Surg Obes Relat Dis. 2005;1(4):399–405. discussion -7. PubMed PMID: 16925257.CrossRefPubMed

33.

Inge T, Zeller M, Jenkins T, et al. Perioperative outcomes of adolescents undergoing bariatric surgery: the teen-longitudinal assessment of bariatric surgery (Teen-LABS) study. JAMA Pediatr. 2014;168(1):47–53.CrossRefPubMedCentralPubMed

34.

Lee D, Guend H, Park K, et al. Outcomes of laparoscopic Roux-en-Y gastric bypass versus laparoscopic adjustable gastric banding in adolescents. Obes Surg. 2012;22(12):1859–64.CrossRefPubMed

35.

Lennerz B, Wabitsch M, Lippert H, et al. Bariatric surgery in adolescents and young adults-safety and effectiveness in a cohort of 345 patients. Int J Obes (2005). 2013.

36.

Messiah S, Lopez-Mitnik G, Winegar D, et al. Changes in weight and co-morbidities among adolescents undergoing bariatric surgery: 1-year results from the Bariatric Outcomes Longitudinal Database. Surg Obes Relat Dis. 2013;9(4):503–13.CrossRefPubMedCentralPubMed

37.

Nadler EP, Youn HA, Ren CJ, et al. An update on 73 US obese pediatric patients treated with laparoscopic adjustable gastric banding: comorbidity resolution and compliance data. J Pediatr Surg. 2008;43(1):141–6. PubMed PMID: 18206472.CrossRefPubMed

38.

Silva GM, Osorio A, Pereira F, et al. Effect of laparoscopic adjustable gastric banding on modifiable cardiovascular risk factors in extremely obese adolescents. Obes Surg. 2012;22(6):991–4. PubMed PMID: 22491997.CrossRefPubMed

39.

Varela JE, Hinojosa MW, Nguyen NT. Perioperative outcomes of bariatric surgery in adolescents compared with adults at academic medical centers. Surg Obes Relat Dis. 2007;3(5):537–40. discussion 41-2. PubMed PMID: 17903775.CrossRefPubMed

40.

Zitsman JL, Fennoy I, Witt MA, et al. Laparoscopic adjustable gastric banding in adolescents: short-term results. J Pediatr Surg. 2011;46(1):157–62. PubMed PMID: 21238658.CrossRefPubMed

41.

De La Cruz-Munoz N, Lopez-Mitnik G, Arheart KL, et al. Effectiveness of bariatric surgery in reducing weight and body mass index among Hispanic adolescents. Obes Surg. 2012. PubMed PMID: 22918552.

42.

Inge TH, Garcia V, Daniels S, et al. A multidisciplinary approach to the adolescent bariatric surgical patient. J Pediatr Surg. 2004;39(3):442–7. discussion 6–7. PubMed PMID: 15017567.CrossRefPubMed

43.

Zwintscher N, Azarow K, Horton J, et al. The increasing incidence of adolescent bariatric surgery. J Pediatr Surg. 2013;48(12):2401–7.CrossRefPubMed

44.

Nijhawan S, Martinez T, Wittgrove AC. Laparoscopic gastric bypass for the adolescent patient: long-term results. Obes Surg. 2012;22(9):1445–9. PubMed PMID: 22638680.CrossRefPubMed

45.

Strauss RS, Bradley LJ, Brolin RE. Gastric bypass surgery in adolscents with morbid obesity. J Pediatr. 2001;138(4):499–504. PubMed PMID: 2001147165.CrossRefPubMed

46.

Cozacov Y, Roy M, Moon S, et al. Mid-term results of laparoscopic sleeve gastrectomy and Roux-en-Y gastric bypass in adolescent patients. Obes Surg. 2014.

47.

Alqahtani AR, Antonisamy B, Alamri H, et al. Laparoscopic sleeve gastrectomy in 108 obese children and adolescents aged 5 to 21 years. Ann Surg. 2012;256(2):266–73. PubMed PMID: 22504281.CrossRefPubMed

48.

Boza C, Viscido G, Salinas J, et al. Laparoscopic sleeve gastrectomy in obese adolescents: results in 51 patients. Surg Obes Relat Dis. 2012;8(2):133–7. discussion 7-9. PubMed PMID: 22433934.CrossRefPubMed

49.

Nadler EP, Qureshi FG, Barefoot L. Early results after laparoscopic sleeve gastrectomy in adolescents with morbid obesity. J Surg Res. 2012 February; Conference: 7th Annual Academic Surgical Congress of the Association for Academic Surgery, AAS and the Society of University Surgeons, SUS Las Vegas, NV United States. Conference Start: 20120214 Conference End: 20120216. Conference Publication: (var.pagings). 172 (2):318-9. PubMed PMID: 70651482.

50.

Pratt J, Lenders C, Dionne E, et al. Best practice updates for pediatric/adolescent weight loss surgery. Obesity (Silver Spring, Md). 2009;17(5):901–10.CrossRef

51.

Miyano G, Jenkins T, Xanthakos S, et al. Perioperative outcome of laparoscopic Roux-en-Y gastric bypass: a children’s hospital experience. J Pediatr Surg. 2013;48(10):2092–8.CrossRefPubMedCentralPubMed

52.

Inge T, Krebs N, Garcia V, et al. Bariatric surgery for severely overweight adolescents: concerns and recommendations. Pediatrics. 2004;114(1):217–23.CrossRefPubMed

53.

Oberbach A, von Bergen M, Bluher S, et al. Combined serum proteomic and metabonomic profiling after laparoscopic sleeve gastrectomy in children and adolescents. J Laparoendosc Adv Surg Tech A. 2012;22(2):184–8. PubMed PMID: 21958229.CrossRefPubMed

54.

NIH conference. Gastrointestinal surgery for severe obesity. Consensus Development Conference Panel. Ann Inter Med. 1991;115(12):956-61.

55.

CA-ADIP. S3-Leitlinie: Chirurgie der Adipositas. http://www.dgavde/fileadmin/media/texte_pdf/caadip/leitlinie-chirurgie-der-adipositas_2010-06.pdf. 2010.

56.

Fried M, Yumuk V, Oppert J-M, et al. Interdisciplinary European guidelines on metabolic and bariatric surgery. Obes Facts. 2013;6(5):449–68.CrossRefPubMed

57.

Nadler EP, Barefoot LC, Qureshi FG. Early results after laparoscopic sleeve gastrectomy in adolescents with morbid obesity. Surgery. 2012;152(2):212–7. PubMed PMID: 22828142.CrossRefPubMed

Title: Bariatric Surgery in Morbidly Obese Adolescents: a Systematic Review and Meta-analysis
Authors: Givan F. Paulus
Loes E. G. de Vaan
Froukje J. Verdam
Nicole D. Bouvy
Ton A. W. Ambergen
L. W. Ernest van Heurn
Publication date: 01-05-2015
Publisher: Springer US
Published in: Obesity Surgery / Issue 5/2015
Print ISSN: 0960-8923
Electronic ISSN: 1708-0428
DOI: https://doi.org/10.1007/s11695-015-1581-2

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Bariatric Surgery in Morbidly Obese Adolescents: a Systematic Review and Meta-analysis

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