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Obesity Surgery
Published in: Obesity Surgery 4/2014

01-04-2014 | Brief Communication

Nonalcoholic Fatty Liver Disease in Morbidly Obese Subjects: Correlation Among Histopathologic Findings, Biochemical Features, and Ultrasound Evaluation

Authors: Everton Cazzo, Fabio de Felice Gallo, José Carlos Pareja, Elinton Adami Chaim

Published in: Obesity Surgery | Issue 4/2014

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Abstract

Nonalcoholic fatty liver disease (NAFLD) has become an important health issue lately. The aim of this study is to determine its prevalence among obese subjects which undergo Roux-en-Y gastric bypass (RYGB). It is a cross-sectional retrospective study involving 164 subjects who underwent RYGB. Clinical, biochemical, and histopathologic features were evaluated. The most common histopathologic features observed were steatohepatitis with fibrosis (29.9 %) and isolated fibrosis (29.3 %). Increased alkaline phosphatase was associated to NAFLD. Dyslipidemia and type 2 diabetes mellitus were associated to NAFLD. Ultrasound had a global accuracy of 78 % to detect NAFLD. Higher prevalence of severe forms of NAFLD was observed compared to previous reports. Most routine biochemical studies had poor correlation with NAFLD and ultrasound was useful but not definitive to detect NAFLD.
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Metadata
Title
Nonalcoholic Fatty Liver Disease in Morbidly Obese Subjects: Correlation Among Histopathologic Findings, Biochemical Features, and Ultrasound Evaluation
Authors
Everton Cazzo
Fabio de Felice Gallo
José Carlos Pareja
Elinton Adami Chaim
Publication date
01-04-2014
Publisher
Springer US
Published in
Obesity Surgery / Issue 4/2014
Print ISSN: 0960-8923
Electronic ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-014-1183-4

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