Skip to main content
Top
Published in: Obesity Surgery 2/2014

01-02-2014 | Original Contributions

Percutaneous Electrical Neurostimulation of Dermatome T6 for Appetite Reduction and Weight Loss in Morbidly Obese Patients

Authors: Jaime Ruiz-Tovar, Inmaculada Oller, María Diez, Lorea Zubiaga, Antonio Arroyo, Rafael Calpena

Published in: Obesity Surgery | Issue 2/2014

Login to get access

Abstract

Background

A continuous feeling of hunger is the major cause of dietary treatment failure in obese patients, making dietary leave. The aim of this study was to evaluate the effect of percutaneous electrical neurostimulation (PENS) of T6 dermatome on appetite, weight loss and dietary compliance.

Methods

A prospective, randomized study was performed. The patients were randomized into two groups: those undergoing PENS of dermatome T6 associated with the implementation of a 1,200-Kcal diet (group 1) and those following only a 1,200-Kcal diet (group 2). A third group of obese patients (BMI > 30 Kg/m2) with fecal incontinence undergoing PENS of posterior tibial nerve was evaluated.

Results

One hundred five patients were included in the study, 45 in groups 1 and 2, and 15 in group 3. The median pain perception after PENS of dermatome T6 was 1. There were no complications. Only the patients in group 1 experienced significant reductions of weight, BMI, and appetite. All of the patients in group 1 experienced appetite reduction compared to 20 % of the patients in group 2 and 30 % of the patients in group 3 (p < 0.001). Weight loss ≥5 Kg was achieved in 76.7 % of the patients in group 1, 6.7 % of the patients in group 2, and 0 % of the patients in group 3 (p < 0.001). Dietary compliance after 12 weeks was 93.3 % in group 1, 56.7 % in group 2, and 50 % in group 3(p = 0.006).

Conclusions

PENS of dermatome T6 was associated with appetite reduction in all of the patients and, along with a proper diet, achieved a significantly greater weight reduction than diet alone.
Literature
2.
go back to reference Sullivan PW, Ghushchyan VH, Ben-Joseph R. The impact of obesity on diabetes, hyperlipidemia and hypertension in the United States. Qual Life Res. 2008;17:1063–71.PubMedCrossRef Sullivan PW, Ghushchyan VH, Ben-Joseph R. The impact of obesity on diabetes, hyperlipidemia and hypertension in the United States. Qual Life Res. 2008;17:1063–71.PubMedCrossRef
3.
go back to reference Nguyen NT, Magno CP, Lane KT, et al. Association of hypertension, diabetes, dyslipidemia and metabolic syndrome with obesity: findings from the National Health and Nutrition Examination Survey 1999 to 2004. J Am Coll Surg. 2008;207:928–34.PubMedCrossRef Nguyen NT, Magno CP, Lane KT, et al. Association of hypertension, diabetes, dyslipidemia and metabolic syndrome with obesity: findings from the National Health and Nutrition Examination Survey 1999 to 2004. J Am Coll Surg. 2008;207:928–34.PubMedCrossRef
4.
go back to reference Martin Duce A, Diez del Val I. Cirugía de la obesidad mórbida. Guías Clínicas de la Asociación Española de Cirujanos. Madrid, Aran, 2007 Martin Duce A, Diez del Val I. Cirugía de la obesidad mórbida. Guías Clínicas de la Asociación Española de Cirujanos. Madrid, Aran, 2007
5.
go back to reference Chen J. Mechanisms of action of the implantable gastric stimulator for obesity. Obes Surg. 2004;14 Suppl 1:S28–32.PubMedCrossRef Chen J. Mechanisms of action of the implantable gastric stimulator for obesity. Obes Surg. 2004;14 Suppl 1:S28–32.PubMedCrossRef
6.
go back to reference Buchwald H, Avidor Y, Braunwald E, et al. Bariatric surgery: a systematic review and meta-analysis. JAMA. 2004;292:1724–37.PubMedCrossRef Buchwald H, Avidor Y, Braunwald E, et al. Bariatric surgery: a systematic review and meta-analysis. JAMA. 2004;292:1724–37.PubMedCrossRef
7.
go back to reference Yao SK, Ke MY, Wang ZF, et al. Visceral response to acute retrograde gastric electrical stimulation in healthy human. World J Gastroenterol. 2005;11:4541–6.PubMed Yao SK, Ke MY, Wang ZF, et al. Visceral response to acute retrograde gastric electrical stimulation in healthy human. World J Gastroenterol. 2005;11:4541–6.PubMed
8.
go back to reference De Luca M, Segato G, Busetto L, et al. Progress in implantable gastric stimulation: summary of results of the European multi-center study. Obes Surg. 2004;14:33–9.CrossRef De Luca M, Segato G, Busetto L, et al. Progress in implantable gastric stimulation: summary of results of the European multi-center study. Obes Surg. 2004;14:33–9.CrossRef
9.
go back to reference Van der Pal F, Van Balken MR, Heesakkers JP, et al. Percutaneous tibial nerve stimulation in the treatment of overactive bladder syndrome: is maintenance treatment a necessity? BJU Int. 2006;97:547–50.PubMedCrossRef Van der Pal F, Van Balken MR, Heesakkers JP, et al. Percutaneous tibial nerve stimulation in the treatment of overactive bladder syndrome: is maintenance treatment a necessity? BJU Int. 2006;97:547–50.PubMedCrossRef
10.
go back to reference Boyle DJ, Prosser K, Allison ME, et al. Percutaneous tibial nerve stimulation for the treatment of urge fecal incontinence. Dis Colon Rectum. 2010;53:432–7.PubMedCrossRef Boyle DJ, Prosser K, Allison ME, et al. Percutaneous tibial nerve stimulation for the treatment of urge fecal incontinence. Dis Colon Rectum. 2010;53:432–7.PubMedCrossRef
11.
go back to reference Sileri P, Franceschilli L, Cadeddu F, et al. Prevalence of defaecatory disordersin morbidly obese patients before and after bariatric surgery. J Gastrointest Surg. 2012;16:62–6.PubMedCrossRef Sileri P, Franceschilli L, Cadeddu F, et al. Prevalence of defaecatory disordersin morbidly obese patients before and after bariatric surgery. J Gastrointest Surg. 2012;16:62–6.PubMedCrossRef
12.
go back to reference Pereira E, Foster A. Appetite suppression and weight loss incidental to spinal cord stimulation for pain relief. Obes Surg. 2007;17:1272–4.PubMedCrossRef Pereira E, Foster A. Appetite suppression and weight loss incidental to spinal cord stimulation for pain relief. Obes Surg. 2007;17:1272–4.PubMedCrossRef
13.
go back to reference Wang J, Song J, Hou X, et al. Effects of cutaneous gastric electrical stimulation on gastric emptying and postprandial satiety and fullness in lean and obese subjects. J Clin Gastroenterol. 2010;44:335–9.PubMed Wang J, Song J, Hou X, et al. Effects of cutaneous gastric electrical stimulation on gastric emptying and postprandial satiety and fullness in lean and obese subjects. J Clin Gastroenterol. 2010;44:335–9.PubMed
14.
go back to reference Yin J, Ouyang H, Wang Z, et al. Cutaneous gastric electrical stimulation alters gastric motility in dogs: new option for gastric electrical stimulation? J Gastroenterol Hepatol. 2009;24:149–54.PubMedCrossRef Yin J, Ouyang H, Wang Z, et al. Cutaneous gastric electrical stimulation alters gastric motility in dogs: new option for gastric electrical stimulation? J Gastroenterol Hepatol. 2009;24:149–54.PubMedCrossRef
15.
go back to reference Abell TL, Minocha A, Abidi N. Looking to the future: electrical stimulation for obesity. Am J Med Sci. 2006;331:226–32.PubMedCrossRef Abell TL, Minocha A, Abidi N. Looking to the future: electrical stimulation for obesity. Am J Med Sci. 2006;331:226–32.PubMedCrossRef
16.
go back to reference Lemanu DP, Srinivasa S, Singh PP, et al. Laparoscopic sleeve gastrectomy: its place in bariatric surgery for the severely obese patient. N Z Med J. 2012;125:41–9.PubMed Lemanu DP, Srinivasa S, Singh PP, et al. Laparoscopic sleeve gastrectomy: its place in bariatric surgery for the severely obese patient. N Z Med J. 2012;125:41–9.PubMed
17.
go back to reference Monga AK, Tracey MR, Subbaroyan J. A systematic review of clinical studies of electrical stimulation for treatment of lower urinary tract dysfunction. Int Urogynecol J. 2012;23:993–1005.PubMedCrossRef Monga AK, Tracey MR, Subbaroyan J. A systematic review of clinical studies of electrical stimulation for treatment of lower urinary tract dysfunction. Int Urogynecol J. 2012;23:993–1005.PubMedCrossRef
18.
go back to reference Findlay JM, Maxwell-Armstrong C. Posterior tibial nerve stimulation and faecal incontinence: a review. Int J Colorectal Dis. 2011;26:265–73.PubMedCrossRef Findlay JM, Maxwell-Armstrong C. Posterior tibial nerve stimulation and faecal incontinence: a review. Int J Colorectal Dis. 2011;26:265–73.PubMedCrossRef
Metadata
Title
Percutaneous Electrical Neurostimulation of Dermatome T6 for Appetite Reduction and Weight Loss in Morbidly Obese Patients
Authors
Jaime Ruiz-Tovar
Inmaculada Oller
María Diez
Lorea Zubiaga
Antonio Arroyo
Rafael Calpena
Publication date
01-02-2014
Publisher
Springer US
Published in
Obesity Surgery / Issue 2/2014
Print ISSN: 0960-8923
Electronic ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-013-1091-z

Other articles of this Issue 2/2014

Obesity Surgery 2/2014 Go to the issue