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Obesity Surgery
Published in: Obesity Surgery 7/2008

01-07-2008 | Review

Nutritional Deficiencies in Morbidly Obese Patients: A New Form of Malnutrition?

Part A: Vitamins

Authors: Orit Kaidar-Person, Benjamin Person, Samuel Szomstein, Raul J. Rosenthal

Published in: Obesity Surgery | Issue 7/2008

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Abstract

It is a common belief that clinical vitamin or mineral deficiencies are rare in Western countries because of the low cost and unlimited diversity of food supply. However, many people consume food that is either unhealthy or of poor nutritional value that lacks proteins, vitamins, minerals, and fiber. In this, article we reviewed the literature and highlighted the vitamin deficiencies in obese patients before bariatric surgery. Deficiency of dietary minerals is described in the accompanying manuscript. The prevalence of vitamin deficiencies in the morbidly obese population prior to bariatric surgery is higher and more significant than previously believed.
Literature
1.
Russell RM. Vitamin and trace mineral deficiency and excess. In: Kasper DL, Fauci AS, Longo DL, Braunwald E, Hauser SL, Jameson JL, editors. Harrison’s principles of internal medicine. Vol 1. 16th ed. McGraw-Hill: Medical Publishing Division; 2005. p. 403.
2.
Glanz K, Basil M, Maibach E, Goldberg J, Snyder D. Why Americans eat what they do: taste, nutrition, cost, convenience, and weight control concerns as influences on food consumption. J Am Diet Assoc. 1998;98(10):1118–26.PubMedCrossRef
3.
Agte V, Tarwadi K, Mengale S, Hinge A, Chiplonkar S. Vitamin profile of cooked foods: how healthy is the practice of ready-to-eat foods? Int J Food Sci Nutr. 2002;53(3):197–208.PubMedCrossRef
4.
Kant AK, Graubard BI, Kumanyika SK. Trends in black-white differentials in dietary intakes of U.S. adults, 1971–2002. Am J Prev Med. 2007;32(4):264–72.PubMedCrossRef
5.
Frazao E, Allshouse J. Strategies for intervention: commentary and debate. Symposium: sugar and fat—from genes to culture. American Society for Nutritional Sciences. J Nutr. 2000;133:844–7.
6.
Nielsen SJ, Popkin BM. Patterns and trends in food portion sizes, 1977–1998. JAMA. 2003;289:450–3.PubMedCrossRef
7.
Shahar D, Shai I, Vardi H, Shahar A, Fraser D. Diet and eating habits in high and low socioeconomic groups. Nutrition. 2005;21:559–66.PubMedCrossRef
8.
Bourre JM. Effects of nutrients (in food) on the structure and function of the nervous system: update on dietary requirements for brain. Part 1: micronutrients. J Nutr Health Aging. 2006;10(5):377–85.PubMed
9.
Bourre JM. Effects of nutrients (in food) on the structure and function of the nervous system: update on dietary requirements for brain. Part 2 : macronutrients. J Nutr Health Aging. 2006;10(5):386–99.PubMed
10.
Bendich A. The potential for dietary supplements to reduce premenstrual syndrome (PMS) symptoms. J Am Coll Nutr. 2000;19(1):3–12.PubMed
11.
Dimopoulos N, Piperi C, Salonicioti A, Psarra V, Gazi F, Nounopoulos C, et al. Association of cognitive impairment with plasma levels of folate, vitamin B12 and homocysteine in the elderly. In Vivo. 2006;20(6B):895–9.PubMed
12.
13.
Konofal E, Lecendreux M, Arnulf I, Mouren MC. Iron deficiency in children with attention-deficit/hyperactivity disorder. Arch Pediatr Adolesc Med. 2004;158(12):1113–5.PubMedCrossRef
14.
Lonsdale D, et al. Crime and Violence: A hypothetical explanation of its relationship with high calorie malnutrition. J Adv Med. 1994;7(3):171–80.
15.
Lopes L, Faintuch J, Kahwage S, de Assis A. A cluster of polyneuropathy and Wernicke–Korsakoff syndrome in a bariatric unit. Obes Surg. 2002;12:328–34.CrossRef
16.
Seehra H, MacDrmontt N, Lascelles R, et al. Lesson of the week: Wernicke’s encephalopathy after vertical banded gastroplasty for morbid obesity. BMJ. 1996;312:434.PubMed
17.
Singh S, Kumar A. Wernicke encephalopathy after obesity surgery: a systematic review. Neurology. 2007 13;68(11):807–11.CrossRef
18.
Tanphaichitr V. Thiamine. In: Shils ME, Olson JA, Shike M, editors. Modern nutrition in heath and disease. Vol. 21. 9th ed. Baltimore: William & Wilkins, 1999. p. 381–89.
19.
Lonsdale D. A review of the biochemistry, metabolism and clinical benefits of thiamin(e) and its derivatives. Evid-Based Complement Altern Med. 2006;3(1):49–59.CrossRef
20.
21.
Carrodeguas L, Kaidar-Person O, Szomstein S, Antozzi P, Rosenthal R. Preoperative thiamine deficiency in obese population undergoing laparoscopic bariatric surgery. Surg Obes Relat Dis. 2005;1(6):517–22.PubMedCrossRef
22.
Flancbaum L, Belsley S, Drake V, Colarusso T, Tayler E. Preoperative nutritional status of patients undergoing Roux-en-Y gastric bypass for morbid obesity. J Gastrointest Surg. 2006;10(7):1033–7.PubMedCrossRef
23.
Cravens DD, Nashelsky J, Oh RC. How do we evaluate a marginally low B12 level? J Fam Pract. 2007;56(1):62–3.PubMed
24.
Hvas AM, Nexo E. Diagnosis and treatment of vitamin B12 deficiency—an update. Haematologica. 2006;91(11):1506–12.PubMed
25.
Oh R, Brown DL. Vitamin B12 deficiency. Am Fam Phys. 2003;1;67(5):979–86.
26.
Nygard O, Nordrehaug JE, Refsum H, Ueland PM, Farstad M, Vollset SE. Plasma homocysteine levels and mortality in patients with coronary artery disease. N Engl J Med. 1997;337:230–6.PubMedCrossRef
27.
Pinhas-Hamiel O, Doron-Panush N, Reichman B, Nitzan-Kaluski D, Shalitin S, Geva-Lerner L. Obese children and adolescents: a risk group for low vitamin B12 concentration. Arch Pediatr Adolesc Med. 2006;160(9):933–6.PubMedCrossRef
28.
Madan AK, Orth WS, Tichansky DS, Ternovits CA. Vitamin and trace mineral levels after laparoscopic gastric bypass. Obes Surg. 2006;16(5):603–6.PubMedCrossRef
29.
Tucker KL, Mahnken B, Wilson PW, Jacques P, Selhub J. Folic acid fortification of the food supply. Potential benefits and risks for the elderly population. JAMA. 1996;276:1879–85.PubMedCrossRef
30.
Giovannucci E, Rimm EB, Ascherio A, Stampfer MJ, Colditz GA, Willett WC. Alcohol, low-methionine-low-folate diets, and risk of colon cancer in men. J Natl Cancer Inst. 1995;15;87(4):265–73.PubMedCrossRef
31.
Rohan TE, Jain MG, Howe GR, Miller AB. Dietary folate consumption and breast cancer risk. J Natl Cancer Ins.t 2000;2;92(3):266–9.PubMedCrossRef
32.
33.
Whittaker P, Tufaro PR, Rader JI. Iron and folate in fortified cereals. J Am Coll Nutr. 2001;20(3):247–54.PubMed
34.
Hey H, Stokholm KH, Lund B, Lund B, Sorensen OH. Vitamin D deficiency in obese patients and changes in circulating vitamin D metabolites following jejunoileal bypass. Int J Obes. 1982;6(5):473–9.PubMed
35.
Andersen T, McNair P, Fogh-Andersen N, Nielsen TT, Hyldstrup L, Transbol I. Increased parathyroid hormone as a consequence of changed complex binding of plasma calcium in morbid obesity. Metabolism. 1986;35(2):147–51.PubMedCrossRef
36.
Buffington C, Walker B, Cowan GS Jr, Scruggs D. Vitamin D deficiency in the morbidly obese. Obes Surg. 1993 Nov;3(4):421–4.PubMedCrossRef
37.
Hamoui N, Anthone G, Crookes PF. Calcium metabolism in the morbidly obese. Obes Surg. 2004;14(1):9–12.PubMedCrossRef
38.
Carlin AM, Rao DS, Meslemani AM, Genaw JA, Parikh NJ, Levy S, et al. Prevalence of vitamin D depletion among morbidly obese patients seeking gastric bypass surgery. Surg Obes Relat Dis. 2006;2(2):98–103.PubMedCrossRef
39.
Carlin AM, Rao DS, Yager KM, Genaw JA, Parikh NJ, Szymanski W. Effect of gastric bypass surgery on vitamin D nutritional status. Surg Obes Relat Dis. 2006;2(6):638–42.PubMedCrossRef
40.
Yanoff LB, Parikh SJ, Spitalnik A, Denkinger B, Sebring NG, Slaughter P, et al. The prevalence of hypovitaminosis D and secondary hyperparathyroidism in obese Black Americans. Clin Endocrinol (Oxf). 2006;64(5):523–9.CrossRef
41.
Abbasi AA, Amin M, Smiertka JK, Grunberger G, MacPherson B, Hares M, et al. Abnormalities of vitamin D and calcium metabolism after surgical treatment of morbid obesity: a study of 136 patients. Endocr Pract. 2007;13(2):131–6.PubMed
42.
Ybarra J, Sanchez-Hernandez J, Perez A. Hypovitaminosis D and morbid obesity. Nurs Clin North Am. 2007;42(1):19–27.PubMedCrossRef
43.
Morinobu T, Murata T, Takaya R, Tamai H. Nutritional status of beta-carotene, alpha-tocopherol and retinol in obese children. Int J Vitam Nutr Res. 2002;72(3):119–23.PubMedCrossRef
44.
Strauss RS. Comparison of serum concentrations of alpha-tocopherol and beta-carotene in a cross-sectional sample of obese and nonobese children (NHANES III). National Health and Nutrition Examination Survey. J Pediatr. 1999;134(2):160–5.PubMedCrossRef
45.
Neuhouser ML, Rock CL, Eldridge AL, Kristal AR, Patterson RE, Cooper DA, et al. Serum concentrations of retinol, alpha-tocopherol and the carotenoids are influenced by diet, race and obesity in a sample of healthy adolescents. J Nutr. 2001;131(8):2184–91.PubMed
46.
Wallstrom P, Wirfalt E, Lahmann PH, Gullberg B, Janzon L, Berglund G. Serum concentrations of beta-carotene and alpha-tocopherol are associated with diet, smoking, and general and central adiposity. Am J Clin Nutr. 2001;73(4):777–85.PubMed
47.
Kimmons JE, Blanck HM, Tohill BC, Zhang J, Khan LK. Associations between body mass index and the prevalence of low micronutrient levels among US adults. MedGenMed. 2006;19;8(4):59.PubMed
48.
Hak AE, Ma J, Powell CB, et al. Prospective study of plasma parotenoids and tocopherols in relation to risk of ischemic stroke. Stroke. 2004;35:1584–8.PubMedCrossRef
49.
Facchini FS, Humphreys MH, DoNascimento CA, Abbasi F, Reaven GM. Relation between insulin resistance and plasma concentrations of lipid hydroperoxides, carotenoids, and tocopherols. Am J Clin Nutr. 2000;72:776–9.PubMed
50.
Ziegler RG. Vegetables, fruits, and carotenoids and the risk of cancer. Am J Clin Nutr. 1991;53 Suppl 1:251–9S.PubMed
51.
Mares-Perlman JA, Millen AE, Ficek TL, Hankinson SE. The body of evidence to support a protective role for lutein and zeaxanthin in delaying chronic disease. Overview. J Nutr. 2002;132:518–24S.PubMed
52.
Levine M, Rumsey SC, Wang Y, Park JB, Daruwala R. Vitamin C. In: Stipanuk MH, editor. Biochemical and physiological aspects of human nutrition. Philadelphia: WB Saunders; 2000. p. 541–67.
53.
Prockop DJ, Kivirikko KI. Collagens: molecular biology, diseases, and potentials for therapy. Annu Rev Biochem. 1995;64:403–34.PubMedCrossRef
54.
Rebouche CJ. Ascorbic acid and carnitine biosynthesis. Am J Clin Nutr. 1991;54:1147–52S.PubMed
55.
56.
57.
Bhat V, Weiner WJ. Parkinson’s disease. Diagnosis and the initiation of therapy. Minerva Med. 2005;96(3):145–54.PubMed
58.
59.
Metadata
Title
Nutritional Deficiencies in Morbidly Obese Patients: A New Form of Malnutrition?
Part A: Vitamins
Authors
Orit Kaidar-Person
Benjamin Person
Samuel Szomstein
Raul J. Rosenthal
Publication date
01-07-2008
Publisher
Springer-Verlag
Published in
Obesity Surgery / Issue 7/2008
Print ISSN: 0960-8923
Electronic ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-007-9349-y

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