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Archives of Osteoporosis

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Open Access 01-12-2022 | Original Article

Physical activity estimated by osteogenic potential and energy expenditure has differing associations with bone mass in young adults: the raine study

Authors: Carrie-Anne Ng, David Scott, Marc Sim, Kun Zhu, Aris Siafarikas, Nicolas H. Hart, Jocelyn Tan, Paola Chivers

Published in: Archives of Osteoporosis | Issue 1/2022

Abstract

Summary

Ground impacts during physical activity may be important for peak bone mass. We found differences in how energy expenditure and impact scores estimated from a physical activity questionnaire related to bone health in young adults. Using both estimate types can improve our understanding of the skeletal benefits of physical activity.

Purpose

It is unclear whether mechanical loading during physical activity, estimated from physical activity questionnaires which assess metabolic equivalents of task (METs), is associated with skeletal health. This longitudinal study investigated how physical activity loading scores, assessed at ages 17 and 20 years, (a) compares with physical activity measured in METs, and (b) is associated with bone mass at age 20 years.

Methods

A total of 826 participants from the Raine Study Gen2 were assessed for physical activity energy expenditure via the International Physical Activity Questionnaire (IPAQ) at age 17 and 20 years. Loading scores (the product of peak force and application rate) per week were subsequently estimated from the IPAQ. Whole-body and appendicular bone mineral density (BMD) at age 20 years were assessed by dual-energy X-ray absorptiometry.

Results

Bland–Altman minimal detectable difference for physical activity Z-

scores at age 17 and 20 years were 1.59 standard deviations (SDs) and 1.33 SDs, respectively, greater than the a priori minimal clinically important change of 0.5 SDs. Loading score, but not IPAQ score, had significant positive associations with whole-body and leg BMD after adjustment for covariates (β = 0.008 and 0.012 g/cm², respectively, for age 17 and 20 years loading scores). IPAQ score at age 20 years, but not loading score, had a significant positive association with arm BMD (β = 0.007 g/cm²).

Conclusion

This study revealed disagreement in associations of self-reported METs and loading score estimates with bone health in young adults. Coupling traditional energy expenditure questionnaire outcomes with bone-loading estimates may improve understanding of the location-specific skeletal benefits of physical activity in young adults.

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Title: Physical activity estimated by osteogenic potential and energy expenditure has differing associations with bone mass in young adults: the raine study
Authors: Carrie-Anne Ng
David Scott
Marc Sim
Kun Zhu
Aris Siafarikas
Nicolas H. Hart
Jocelyn Tan
Paola Chivers
Publication date: 01-12-2022
Publisher: Springer London
Published in: Archives of Osteoporosis / Issue 1/2022
Print ISSN: 1862-3522
Electronic ISSN: 1862-3514
DOI: https://doi.org/10.1007/s11657-022-01100-1

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Physical activity estimated by osteogenic potential and energy expenditure has differing associations with bone mass in young adults: the raine study

Abstract

Summary

Purpose

Methods

Results

Conclusion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Summary

Purpose

Methods

Results

Conclusion

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