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Published in: Archives of Osteoporosis 1/2019

Open Access 01-12-2019 | Osteoporosis | Short Communication

The impact of hip fracture on health-related quality of life and activities of daily living: the SPARE-HIP prospective cohort study

Authors: D. Prieto-Alhambra, D. Moral-Cuesta, A. Palmer, I. Aguado-Maestro, M. F. Bravo Bardaji, F. Brañas, G. Adrados Bueno, J. R. Caeiro-Rey, I. Andrés Cano, M. Barres-Carsi, L. Gracia Delgado, M. Salomó-Domènech, I. Etxebarria-Foronda, B. Llado Ferrer, S. Mills, L. Ezquerra Herrando, D. Mifsut, L. D. R. Evangelista, X. Nogués, I. Perez-Coto, J. Martínez-Iñiguez Blasco, C. Martín-Hernández, H. Kessel, J. Teixidor Serra, J. Rodriguez Solis, O. Torregrosa Suau, E. Vaquero-Cervino, C. Pablos Hernández, L. Rodríguez Mañas, A. Herrera, A. Díez-Perez

Published in: Archives of Osteoporosis | Issue 1/2019

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Abstract

Purpose

The medical morbidity and mortality associated with neck of femur fractures is well-documented, whereas there is limited data for patient-reported outcomes. The aim of this study was to characterize the impact of neck of femur fractures on activities of daily living and patient-reported health-related quality of life.

Methods

Design and participants: Multicentric prospective cohort study. Consecutive sample patients with fragility hip fracture over 50 years old admitted in 48 hospitals in Spain.
Outcomes: daily living activity function (Barthel Index) and health-related quality of life (EQ-5D) pre-fracture, admission to hospital and at 1- and 4-month follow-up post-fracture.
Statistics: Barthel and EQ-5D over time are described as mean (SD) and median (interquartile range).

Results

A total of 997 patients were recruited at baseline with 4-month outcomes available for, and 856 patients (89.5%). Barthel Index fell from 78.77 (23.75) at baseline to 43.62 (19.86) on admission to hospital with the fracture. Scores partially recovered to 54.89 (25.40) and 64.09 (21.35) at 1- and 4-month post-fracture, respectively. EQ-5D fell from a median of 0.75 (0.47–0.91) to − 0.01 (− 0.03 to 0.51) on admission. Partial recovery was observed again to (0.51 (− 0.06 to 0.67)) and (0.60 (0.10 to 0.80)) at 1- and 4-month post-fracture, respectively.

Conclusions

Hip fracture results in a large decline in the ability to perform activities of daily living and patient-reported health-related quality of life with only partial recovery amongst survivors 4-month post-fracture.
Literature
1.
go back to reference Pedersen AB, Ehrenstein V, Szépligeti SK, Lunde A, Lagerros YT, Westerlund A, Tell GS, Sørensen HT (2017) Thirty-five–year trends in first-time hospitalization for hip fracture, 1-year mortality, and the prognostic impact of comorbidity: a Danish nationwide cohort study, 1980–2014. Epidemiology 28(6):898–905CrossRef Pedersen AB, Ehrenstein V, Szépligeti SK, Lunde A, Lagerros YT, Westerlund A, Tell GS, Sørensen HT (2017) Thirty-five–year trends in first-time hospitalization for hip fracture, 1-year mortality, and the prognostic impact of comorbidity: a Danish nationwide cohort study, 1980–2014. Epidemiology 28(6):898–905CrossRef
2.
go back to reference Svedbom A, Hernlund E, Ivergård M, Compston J, Cooper C, Stenmark J et al (2013) Osteoporosis in the European Union: a compendium of country-specific reports. Arch Osteoporos 8(1–2):137CrossRef Svedbom A, Hernlund E, Ivergård M, Compston J, Cooper C, Stenmark J et al (2013) Osteoporosis in the European Union: a compendium of country-specific reports. Arch Osteoporos 8(1–2):137CrossRef
3.
go back to reference Cooper C, Campion G, Melton LJ 3rd (1992) Hip fractures in the elderly: a world-wide projection. Osteoporos Int 2(6):285–289CrossRef Cooper C, Campion G, Melton LJ 3rd (1992) Hip fractures in the elderly: a world-wide projection. Osteoporos Int 2(6):285–289CrossRef
4.
go back to reference Borgström F, Lekander I, Ivergård M, Ström O, Svedbom A, Alekna V, Bianchi ML, Clark P, Curiel MD, Dimai HP, Jürisson M, Kallikorm R, Lesnyak O, McCloskey E, Nassonov E, Sanders KM, Silverman S, Tamulaitiene M, Thomas T, Tosteson ANA, Jönsson B, Kanis JA (2013) The international costs and utilities related to osteoporotic fractures study (ICUROS)—quality of life during the first 4 months after fracture. Osteoporos Int 24(3):811–823CrossRef Borgström F, Lekander I, Ivergård M, Ström O, Svedbom A, Alekna V, Bianchi ML, Clark P, Curiel MD, Dimai HP, Jürisson M, Kallikorm R, Lesnyak O, McCloskey E, Nassonov E, Sanders KM, Silverman S, Tamulaitiene M, Thomas T, Tosteson ANA, Jönsson B, Kanis JA (2013) The international costs and utilities related to osteoporotic fractures study (ICUROS)—quality of life during the first 4 months after fracture. Osteoporos Int 24(3):811–823CrossRef
5.
go back to reference Marques A, Lourenço Ó, da Silva J (2015) The burden of osteoporotic hip fractures in Portugal: costs, health related quality of life and mortality. Osteoporos Int 26(11):2623–2630CrossRef Marques A, Lourenço Ó, da Silva J (2015) The burden of osteoporotic hip fractures in Portugal: costs, health related quality of life and mortality. Osteoporos Int 26(11):2623–2630CrossRef
6.
go back to reference Prieto-Alhambra D, Reyes C, Sainz MS, González-Macías J, Delgado LG, Bouzón CA, Gañan SM, Miedes DM, Vaquero-Cervino E, Bardaji MFB, Herrando LE, Baztán FB, Ferrer BL, Perez-Coto I, Bueno GA, Mora-Fernandez J, Doñate TE, Blasco JMI, Aguado-Maestro I, Sáez-López P, Doménech MS, Climent-Peris V, Rodríguez ÁD, Sardiñas HK, Gómez ÓT, Serra JT, Caeiro-Rey JR, Cano IA, Carsi MB, Etxebarria-Foronda I, Hernández JDA, Solis JR, Suau OT, Nogués X, Herrera A, Díez-Perez A (2018) In-hospital care, complications, and 4-month mortality following a hip or proximal femur fracture: the Spanish registry of osteoporotic femur fractures prospective cohort study. Arch Osteoporos 13(1):96CrossRef Prieto-Alhambra D, Reyes C, Sainz MS, González-Macías J, Delgado LG, Bouzón CA, Gañan SM, Miedes DM, Vaquero-Cervino E, Bardaji MFB, Herrando LE, Baztán FB, Ferrer BL, Perez-Coto I, Bueno GA, Mora-Fernandez J, Doñate TE, Blasco JMI, Aguado-Maestro I, Sáez-López P, Doménech MS, Climent-Peris V, Rodríguez ÁD, Sardiñas HK, Gómez ÓT, Serra JT, Caeiro-Rey JR, Cano IA, Carsi MB, Etxebarria-Foronda I, Hernández JDA, Solis JR, Suau OT, Nogués X, Herrera A, Díez-Perez A (2018) In-hospital care, complications, and 4-month mortality following a hip or proximal femur fracture: the Spanish registry of osteoporotic femur fractures prospective cohort study. Arch Osteoporos 13(1):96CrossRef
7.
go back to reference Collin C, Wade D, Davies S, Horne V (1988) The Barthel ADL Index: a reliability study. Disability and rehabilitation 10(2):61–63 Collin C, Wade D, Davies S, Horne V (1988) The Barthel ADL Index: a reliability study. Disability and rehabilitation 10(2):61–63
8.
go back to reference EuroQol G (1990) EuroQol--a new facility for the measurement of health-related quality of life. Health policy 16(3):199 EuroQol G (1990) EuroQol--a new facility for the measurement of health-related quality of life. Health policy 16(3):199
9.
go back to reference Badia X, Roset M, Herdman M, Kind P (2001) A comparison of United Kingdom and Spanish general population time trade-off values for EQ-5D health states. Med Decis Mak 21(1):7–16CrossRef Badia X, Roset M, Herdman M, Kind P (2001) A comparison of United Kingdom and Spanish general population time trade-off values for EQ-5D health states. Med Decis Mak 21(1):7–16CrossRef
10.
go back to reference Griffin X, Parsons N, Achten J, Fernandez M, Costa M (2015) Recovery of health-related quality of life in a United Kingdom hip fracture population: the Warwick hip trauma evaluation-a prospective cohort study. Bone Joint J 97(3):372–382CrossRef Griffin X, Parsons N, Achten J, Fernandez M, Costa M (2015) Recovery of health-related quality of life in a United Kingdom hip fracture population: the Warwick hip trauma evaluation-a prospective cohort study. Bone Joint J 97(3):372–382CrossRef
11.
go back to reference Gjertsen J-E, Baste V, Fevang JM, Furnes O, Engesæter LB (2016) Quality of life following hip fractures: results from the Norwegian hip fracture register. BMC Musculoskelet Disord 17(1):265CrossRef Gjertsen J-E, Baste V, Fevang JM, Furnes O, Engesæter LB (2016) Quality of life following hip fractures: results from the Norwegian hip fracture register. BMC Musculoskelet Disord 17(1):265CrossRef
12.
go back to reference Caeiro JR, Bartra A, Mesa-Ramos M, Etxebarría Í, Montejo J, Carpintero P et al (2017) Burden of first osteoporotic hip fracture in Spain: a prospective, 12-month, observational study. Calcif Tissue Int 100(1):29–39CrossRef Caeiro JR, Bartra A, Mesa-Ramos M, Etxebarría Í, Montejo J, Carpintero P et al (2017) Burden of first osteoporotic hip fracture in Spain: a prospective, 12-month, observational study. Calcif Tissue Int 100(1):29–39CrossRef
13.
go back to reference Ruths S, Baste V, Bakken MS, Engesæter LB, Lie SA, Haugland S (2017) Municipal resources and patient outcomes through the first year after a hip fracture. BMC Health Serv Res 17(1):144CrossRef Ruths S, Baste V, Bakken MS, Engesæter LB, Lie SA, Haugland S (2017) Municipal resources and patient outcomes through the first year after a hip fracture. BMC Health Serv Res 17(1):144CrossRef
14.
go back to reference Vergara I, Vrotsou K, Orive M, Gonzalez N, Garcia S, Quintana JM (2014) Factors related to functional prognosis in elderly patients after accidental hip fractures: a prospective cohort study. BMC Geriatr 14(1):124CrossRef Vergara I, Vrotsou K, Orive M, Gonzalez N, Garcia S, Quintana JM (2014) Factors related to functional prognosis in elderly patients after accidental hip fractures: a prospective cohort study. BMC Geriatr 14(1):124CrossRef
15.
go back to reference Costa ML, Griffin XL, Achten J, Metcalfe D, Judge A, Pinedo-Villanueva R, Parsons N (2016) World hip trauma evaluation (WHiTE): framework for embedded comprehensive cohort studies. BMJ Open 6(10):e011679CrossRef Costa ML, Griffin XL, Achten J, Metcalfe D, Judge A, Pinedo-Villanueva R, Parsons N (2016) World hip trauma evaluation (WHiTE): framework for embedded comprehensive cohort studies. BMJ Open 6(10):e011679CrossRef
16.
go back to reference Moerman S, Vochteloo AJ, Tuinebreijer WE, Maier AB, Mathijssen NM, Nelissen RG (2016) Factors associated with the course of health-related quality of life after a hip fracture. Arch Orthop Trauma Surg 136(7):935–943CrossRef Moerman S, Vochteloo AJ, Tuinebreijer WE, Maier AB, Mathijssen NM, Nelissen RG (2016) Factors associated with the course of health-related quality of life after a hip fracture. Arch Orthop Trauma Surg 136(7):935–943CrossRef
Metadata
Title
The impact of hip fracture on health-related quality of life and activities of daily living: the SPARE-HIP prospective cohort study
Authors
D. Prieto-Alhambra
D. Moral-Cuesta
A. Palmer
I. Aguado-Maestro
M. F. Bravo Bardaji
F. Brañas
G. Adrados Bueno
J. R. Caeiro-Rey
I. Andrés Cano
M. Barres-Carsi
L. Gracia Delgado
M. Salomó-Domènech
I. Etxebarria-Foronda
B. Llado Ferrer
S. Mills
L. Ezquerra Herrando
D. Mifsut
L. D. R. Evangelista
X. Nogués
I. Perez-Coto
J. Martínez-Iñiguez Blasco
C. Martín-Hernández
H. Kessel
J. Teixidor Serra
J. Rodriguez Solis
O. Torregrosa Suau
E. Vaquero-Cervino
C. Pablos Hernández
L. Rodríguez Mañas
A. Herrera
A. Díez-Perez
Publication date
01-12-2019
Publisher
Springer London
Published in
Archives of Osteoporosis / Issue 1/2019
Print ISSN: 1862-3522
Electronic ISSN: 1862-3514
DOI
https://doi.org/10.1007/s11657-019-0607-0

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