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Journal of Gastrointestinal Surgery

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01-04-2018 | Original Article

Comparison of Hepatectomy for Patients with Metabolic Syndrome-Related HCC and HBV-Related HCC

Authors: Yunhong Tian, Huan Lyu, Yunhong He, Yong Xia, Jun Li, Feng Shen

Published in: Journal of Gastrointestinal Surgery | Issue 4/2018

Abstract

Background

Metabolic syndrome (MetS) is a group of clinicopathological manifestations. The outcome of liver surgery in metabolic syndrome-related hepatocellular carcinoma (MetS-HCC) still needs to be evaluated. We aim to clarify the outcomes following liver resection in patients with MetS-HCC compared those with hepatitis B virus-related HCC (HBV-HCC).

Methods

All the consecutive patients undergoing hepatectomy for HCC between January 2009 and December 2012 were retrospectively considered. Patients were divided into three groups: MetS-HCC, MetS-HBV-HCC, and HBV-HCC. Data on clinical characteristics, postoperative complications, and long-term outcome were collected and analyzed.

Results

A total of 1352 patients were included in this study. In MetS-HCC group, the severe morbidity rate was 33.33%, which was higher than that of HBV-HCC group (15.68%). In subgroup analysis, patients with MetS-HCC in American Joint Committee on Cancer (AJCC) stage I had superior DFS and OS when compared with those of the other two groups.

Conclusions

We should pay more attention to patients with MetS-HCC perioperatively due to the high rate of surgical complications. Nevertheless, curative treatment should be provided to patients with MetS.

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Title: Comparison of Hepatectomy for Patients with Metabolic Syndrome-Related HCC and HBV-Related HCC
Authors: Yunhong Tian
Huan Lyu
Yunhong He
Yong Xia
Jun Li
Feng Shen
Publication date: 01-04-2018
Publisher: Springer US
Published in: Journal of Gastrointestinal Surgery / Issue 4/2018
Print ISSN: 1091-255X
Electronic ISSN: 1873-4626
DOI: https://doi.org/10.1007/s11605-017-3629-1

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Comparison of Hepatectomy for Patients with Metabolic Syndrome-Related HCC and HBV-Related HCC

Abstract

Background

Methods

Results

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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