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Open Access 01-08-2015 | Original Article

Visceral Obesity Predicts Fewer Lymph Node Metastases and Better Overall Survival in Colon Cancer

Authors: Se Woo Park, Hang Lak Lee, Eun Young Doo, Kang Nyeong Lee, Dae Won Jun, Oh Young Lee, Dong Soo Han, Byung Chul Yoon, Ho Soon Choi, Kang Hong Lee

Published in: Journal of Gastrointestinal Surgery | Issue 8/2015

Abstract

Background

The relationship between visceral obesity and colon cancer outcome has not been well studied. The goal of this study was to determine the impact of visceral obesity on lymph node (LN) metastasis and overall survival (OS) in colon cancer.

Materials and Methods

Metastatic LN ratio (MLR) was defined as the number of involved nodes by tumor divided by the total number of resected LNs. Visceral (VFA) and subcutaneous fat areas (SFA) were determined by measuring abdominal fat volume distribution via CT scan, and visceral obesity was defined as a VFA to total fat area ratio (V/T) > 0.29.

Results

In a multivariate analysis among 186 patients, there were inverse associations between V/T and MLR (OR = 0.413, 95 % CI = 0.216–0.789, P = 0.007). Furthermore, patients with visceral obesity tended to have significantly better OS than patients with non-visceral obesity.

Conclusions

Higher V/T ratios which indicate referring to visceral obesity was significantly associated with decreased MLR and better OS for CRC.

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Title: Visceral Obesity Predicts Fewer Lymph Node Metastases and Better Overall Survival in Colon Cancer
Authors: Se Woo Park
Hang Lak Lee
Eun Young Doo
Kang Nyeong Lee
Dae Won Jun
Oh Young Lee
Dong Soo Han
Byung Chul Yoon
Ho Soon Choi
Kang Hong Lee
Publication date: 01-08-2015
Publisher: Springer US
Published in: Journal of Gastrointestinal Surgery / Issue 8/2015
Print ISSN: 1091-255X
Electronic ISSN: 1873-4626
DOI: https://doi.org/10.1007/s11605-015-2834-z

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Visceral Obesity Predicts Fewer Lymph Node Metastases and Better Overall Survival in Colon Cancer

Abstract

Background

Materials and Methods

Results

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Materials and Methods

Results

Conclusions

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