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Journal of Gastrointestinal Surgery
Published in: Journal of Gastrointestinal Surgery 5/2015

01-05-2015 | GI Image

False-Positive PET/CT After Cyanoacrylate Sealing of a Pancreaticojejunostomy

Authors: Orlin Belyaev, Johanna Munding, Andrea Tannapfel, Waldemar Uhl

Published in: Journal of Gastrointestinal Surgery | Issue 5/2015

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Abstract

In 2013, a 68-year-old male had a pancreaticoduodenectomy for pancreatic cancer. The pancreaticojejunostomy was sealed with cyanoacrylate (Dermabond) to prevent postoperative pancreatic fistula. Local recurrence of malignancy at the anastomosis was suspected 18 months later in PET/CT. Surgical revision was performed and anastomosis resected. However, histology showed no tumor recurrence, but strong inflammation and foreign-body reaction towards Dermabond. The sealant caused false-positive PET/CT findings, so its use in oncologic surgery should be abandoned.
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Lämsä T, Jin HT, Sand J, Nordback I. Tissue adhesives and the pancreas: biocompatibility and adhesive properties of 6 preparations. Pancreas. 2008;36:261-266.CrossRefPubMed
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Barakat O, Ozaki CF, Wood RP. Topically applied 2-octyl cyanoacrylate (Dermabond) for prevention of postoperative pancreatic fistula after pancreaticoduodenectomy. J Gastrointest Surg. 2012;16:1499-507.CrossRefPubMed
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Metadata
Title
False-Positive PET/CT After Cyanoacrylate Sealing of a Pancreaticojejunostomy
Authors
Orlin Belyaev
Johanna Munding
Andrea Tannapfel
Waldemar Uhl
Publication date
01-05-2015
Publisher
Springer US
Published in
Journal of Gastrointestinal Surgery / Issue 5/2015
Print ISSN: 1091-255X
Electronic ISSN: 1873-4626
DOI
https://doi.org/10.1007/s11605-015-2780-9

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