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Published in: Journal of Gastrointestinal Surgery 4/2014

01-04-2014 | Case Report

Surgery for Giant Primary Neuroendocrine Carcinoma of the Liver

Authors: Georgios C. Sotiropoulos, Petros Charalampoudis, Ioanna Delladetsima, Paraskevas Stamopoulos, Spyridon Dourakis, Gregory Kouraklis

Published in: Journal of Gastrointestinal Surgery | Issue 4/2014

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Abstract

Liver resection for primary hepatic neuroendocrine carcinoma (phNEC) has only scarcely been reported in the literature. We herein report on a 19-year-old female with a solitary 27 × 13-cm-big phNEC, which was initially considered as hemangioma. An extended right hepatectomy (segments V–VIII, partially IVa) was performed. Resection margins were free of tumor (R0 resection). Ki67 expression was 35 %. Postoperative course was uneventful, and the patient was discharged on the seventh postoperative day. Two years after surgery, the patient remains disease-free and in good general condition. Large series and longer follow-up studies are required for the better understanding on this rare tumor entity.
Literature
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go back to reference Gurung A, Yoshida EM, Scudamore CH, et al. Primary hepatic neuroendocrine tumour requiring live donor liver transplantation: case report and concise review. Ann Hepatol 2012;11:715–20PubMed Gurung A, Yoshida EM, Scudamore CH, et al. Primary hepatic neuroendocrine tumour requiring live donor liver transplantation: case report and concise review. Ann Hepatol 2012;11:715–20PubMed
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go back to reference Dong M, Phan AT, Yao JC. New strategies for advanced neuroendocrine tumors in the era of targeted therapy. Clin Cancer Res 2012;18:1830–6.PubMedCrossRef Dong M, Phan AT, Yao JC. New strategies for advanced neuroendocrine tumors in the era of targeted therapy. Clin Cancer Res 2012;18:1830–6.PubMedCrossRef
Metadata
Title
Surgery for Giant Primary Neuroendocrine Carcinoma of the Liver
Authors
Georgios C. Sotiropoulos
Petros Charalampoudis
Ioanna Delladetsima
Paraskevas Stamopoulos
Spyridon Dourakis
Gregory Kouraklis
Publication date
01-04-2014
Publisher
Springer US
Published in
Journal of Gastrointestinal Surgery / Issue 4/2014
Print ISSN: 1091-255X
Electronic ISSN: 1873-4626
DOI
https://doi.org/10.1007/s11605-013-2346-7

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