Top

Journal of Gastrointestinal Surgery

Published in:

01-03-2014 | Case Report

Primary Hepatic Ewing’s Sarcoma with Cytogenetic Confirmation

Authors: P. F. McGrann, I. J. Pooleman, C. H. Wilson, B. Haugk, J. Scott, R. M. Charnley

Published in: Journal of Gastrointestinal Surgery | Issue 3/2014

Abstract

Introduction

Extraskeletal Ewing’s sarcoma is reported in the medical literature, but none has been described as presenting with a resectable liver mass.

Methods

A case of a 29-year-old male patient who presented with a large symptomatic mass in the right lobe of the liver which, following resection, demonstrated the characteristic histopathology and fusion protein (EWSR1-Fli1) found in Ewing’s sarcoma was reported.

Discussion

Complete surgical resection offers the best long-term outlook. Cure rates with appropriate surgical and chemotherapeutic management range between 30 and 60 %.

Pinto A, Dickman P, Parham D: Pathobiologic markers of the Ewing sarcoma family of tumors: state of the art and prediction of behaviour. Sarcoma 2011;2011:856190.PubMedCentralPubMedCrossRef

Applebaum MA, Worch J, Matthay KK, et al.: Clinical features and outcomes in patients with extraskeletal Ewing sarcoma. Cancer 2011;117:3027–3032.PubMedCentralPubMedCrossRef

Ahmad R, Mayol BR, Davis M, et al.: Extraskeletal Ewing’s sarcoma. Cancer 1999;85:725–731.PubMedCrossRef

Mani S, Dutta D, De BK: Primitive neuroectodermal tumor of the liver: a case report. Jpn J Clin Oncol 2010;40:258–262.PubMedCrossRef

Balasubramanian SK, Jittiwat J, Manikandan J, et al.: Biodistribution of gold nanoparticles and gene expression changes in the liver and spleen after intravenous administration in rats. Biomaterials 2010;31:2034–2042.PubMedCrossRef

Marques M, Cardoso H, Barroca H, et al.: Peripheral primitive neuroectodermal tumour of the liver: a case report and review of the literature. Gastroenterol Hepatol 2011;34:611–613.PubMedCrossRef

Cambruzzi E, Guerra EE, Hilgert HC, et al.: Primitive neuroectodermal tumor of the liver: a case report. Case Report Med 2011;2011:748194.

Verrill MW, Judson IR, Harmer CL, et al.: Ewing’s sarcoma and primitive neuroectodermal tumor in adults: are they different from Ewing's sarcoma and primitive neuroectodermal tumor in children? J Clin Oncol 1997;15:2611–2621.PubMed

Tural D, Molinas Mandel N, Dervisoglu S, et al.: Extraskeletal Ewing’s sarcoma family of tumors in adults: prognostic factors and clinical outcome. Jpn J Clin Oncol 2012;42:420–426.PubMedCrossRef

10.

Kallala R, Nikkhah D, Nix P, et al.: Primary extraskeletal Ewing sarcoma involving the carotid artery: a case report and review of the current literature. Ann R Coll Surg Engl 2012;94:141–143.CrossRef

Title: Primary Hepatic Ewing’s Sarcoma with Cytogenetic Confirmation
Authors: P. F. McGrann
I. J. Pooleman
C. H. Wilson
B. Haugk
J. Scott
R. M. Charnley
Publication date: 01-03-2014
Publisher: Springer US
Published in: Journal of Gastrointestinal Surgery / Issue 3/2014
Print ISSN: 1091-255X
Electronic ISSN: 1873-4626
DOI: https://doi.org/10.1007/s11605-013-2284-4

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Primary Hepatic Ewing’s Sarcoma with Cytogenetic Confirmation

Abstract

Introduction

Methods

Discussion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Introduction

Methods

Discussion

Please log in to get access to this content

Other articles of this Issue 3/2014

Intranodal Lymphangiogenesis Precedes Development of Lymph Node Metastasis and Accelerates Progression of Gastric Cancer

A Simple and Safe Method for Billroth I Reconstruction in Single-Incision Laparoscopic Gastrectomy Using a Novel Intracorporeal Triangular Anastomotic Technique

Value of Geriatric Frailty and Nutritional Status Assessment in Predicting Postoperative Mortality in Gastric Cancer Surgery

Image Findings in Celiac Artery Stenosis Due to Median Arcuate Ligament Compression

The Study on the Efficacy of Fibrin Glue in Preventing Post-traumatic Focal Pancreatitis (PTFP) After Radical Gastrectomy

Surgery Versus Transarterial Chemoembolization for Solitary Large Hepatocellular Carcinoma of BCLC Stage A