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Published in: Journal of Gastrointestinal Surgery 9/2013

01-09-2013 | Case Report

Ectopic Bone in the Abdominal Cavity: A Surgical Nightmare

Authors: Zachary Torgersen, Angela Osmolak, Jai Bikhchandani, Armour R. Forse

Published in: Journal of Gastrointestinal Surgery | Issue 9/2013

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Abstract

Introduction

Heterotopic mesenteric ossification (HMO) is a rare clinical entity with less than 40 reported cases in the literature. Frequently associated with prior abdominal surgery or trauma, the precise etiology and optimal approach to its management remain undefined.

Case Report

The index patient is a 58-year-old male who originally presented with perforated diverticulitis. Following resection, the patient developed an enterocutaneous fistula. After a trial of conservative management, the patient underwent exploration and was found to have widespread intra-abdominal calcification. Sheets of calcific tissue were resected, and a diagnosis of HMO was confirmed via pathology. The patient had a postoperative course complicated by bleeding and redevelopment of enteric fistula. Following a prolonged hospital course requiring multiple operations, the fistula persists, and the patient remains on parenteral nutrition.

Discussion

The etiology of HMO is unknown. Diagnosis requires a high degree of clinical suspicion, as radiologic findings are often misleading. A review of 18 cases demonstrates significant morbidity associated with operative intervention. Nonsteroidals, in particular indomethacin, have been shown to decrease heterotopic ossification, but their role in mesenteric disease is not clearly defined.

Conclusion

HMO is a rare but complicated pathologic process. A trial of conservative management with NSAIDs, bowel rest, and total parenteral nutrition is prudent, given the high rate of morbidity and mortality associated with operative intervention.
Literature
1.
go back to reference Kaplan FS, Glaser DL, Hebela N, Shore EM . Heterotopic Ossification. The Journal of the American Academy of Orthopaedic Surgeons 2004;12:116–125.PubMed Kaplan FS, Glaser DL, Hebela N, Shore EM . Heterotopic Ossification. The Journal of the American Academy of Orthopaedic Surgeons 2004;12:116–125.PubMed
2.
go back to reference Tonino BA, van der Meulen HG, Kuijpers KC, Mallens WM, van Gils AP . Heterotropic Mesenteric Ossification: A Case Report (2004:10b). European Radiology 2005;15:195–197.PubMedCrossRef Tonino BA, van der Meulen HG, Kuijpers KC, Mallens WM, van Gils AP . Heterotropic Mesenteric Ossification: A Case Report (2004:10b). European Radiology 2005;15:195–197.PubMedCrossRef
3.
go back to reference Lemeshev Y, Lahr CJ, Denton J, Kent SP, Diethelm AG. Heterotopic Bone Formation Associated with Intestinal Obstruction and Small Bowel Resection. The Alabama Journal of Medical Sciences 1983;20:314–317.PubMed Lemeshev Y, Lahr CJ, Denton J, Kent SP, Diethelm AG. Heterotopic Bone Formation Associated with Intestinal Obstruction and Small Bowel Resection. The Alabama Journal of Medical Sciences 1983;20:314–317.PubMed
4.
go back to reference Wilson JD, Montague CJ, Salcuni P, Bordi C, Rosai J. Heterotopic Mesenteric Ossification ('Intraabdominal Myositis Ossificans'): Report of Five Cases. The American Journal of Surgical Pathology 1999;23:1464–1470.PubMedCrossRef Wilson JD, Montague CJ, Salcuni P, Bordi C, Rosai J. Heterotopic Mesenteric Ossification ('Intraabdominal Myositis Ossificans'): Report of Five Cases. The American Journal of Surgical Pathology 1999;23:1464–1470.PubMedCrossRef
5.
go back to reference Marteinsson BT, Musgrove JE. Heterotopic Bone Formation in Abdominal Incisions. American Journal of Surgery 1975;130:23–25.PubMedCrossRef Marteinsson BT, Musgrove JE. Heterotopic Bone Formation in Abdominal Incisions. American Journal of Surgery 1975;130:23–25.PubMedCrossRef
6.
go back to reference Lai HJ, Jao SW, Lee TY, Ou JJ, Kang JC. Heterotopic Mesenteric Ossification After Total Colectomy for Bleeding Diverticulosis of the Colon--a Rare Case Report. Journal of the Formosan Medical Association = Taiwan Yi Zhi 2007;106:S32-6.PubMedCrossRef Lai HJ, Jao SW, Lee TY, Ou JJ, Kang JC. Heterotopic Mesenteric Ossification After Total Colectomy for Bleeding Diverticulosis of the Colon--a Rare Case Report. Journal of the Formosan Medical Association = Taiwan Yi Zhi 2007;106:S32-6.PubMedCrossRef
7.
go back to reference Baker JC, Menias CO, Bhalla S. Bone in the Belly: Traumatic Heterotopic Mesenteric Ossification. Emergency Radiology 2012;19:429–436.PubMedCrossRef Baker JC, Menias CO, Bhalla S. Bone in the Belly: Traumatic Heterotopic Mesenteric Ossification. Emergency Radiology 2012;19:429–436.PubMedCrossRef
8.
go back to reference Androulaki A, Chatzoulis G, Kalahanis N, Lazaris AC. Heterotopic Mesenteric Ossification: A Rare Reactive Process. Journal of Gastroenterology and Hepatology 2005;20:664–666.PubMedCrossRef Androulaki A, Chatzoulis G, Kalahanis N, Lazaris AC. Heterotopic Mesenteric Ossification: A Rare Reactive Process. Journal of Gastroenterology and Hepatology 2005;20:664–666.PubMedCrossRef
9.
go back to reference Christofi T, Raptis DA, Kallis A, Ambasakoor F. True Trilineage Haematopoiesis in Excised Heterotopic Ossification from a Laparotomy Scar: Report of a Case and Literature Review. Annals of the Royal College of Surgeons of England 2008;90:W12-4.PubMedCrossRef Christofi T, Raptis DA, Kallis A, Ambasakoor F. True Trilineage Haematopoiesis in Excised Heterotopic Ossification from a Laparotomy Scar: Report of a Case and Literature Review. Annals of the Royal College of Surgeons of England 2008;90:W12-4.PubMedCrossRef
10.
go back to reference Hakim M, McCarthy EF. Heterotopic Mesenteric Ossification. AJR. American Journal of Roentgenology 2001;176:260–261.PubMedCrossRef Hakim M, McCarthy EF. Heterotopic Mesenteric Ossification. AJR. American Journal of Roentgenology 2001;176:260–261.PubMedCrossRef
11.
go back to reference Myers MA, Minton JP. Heterotopic Ossification within the Small-Bowel Mesentery. Archives of Surgery (Chicago, Ill.: 1960) 1989;124:982–983.CrossRef Myers MA, Minton JP. Heterotopic Ossification within the Small-Bowel Mesentery. Archives of Surgery (Chicago, Ill.: 1960) 1989;124:982–983.CrossRef
12.
go back to reference Yushuva A, Nagda P, Suzuki K, Llaguna OH, Avgerinos D, Goodman E. Heterotopic Mesenteric Ossification Following Gastric Bypass Surgery: Case Series and Review of Literature. Obesity Surgery 2010;20:1312–1315.PubMedCrossRef Yushuva A, Nagda P, Suzuki K, Llaguna OH, Avgerinos D, Goodman E. Heterotopic Mesenteric Ossification Following Gastric Bypass Surgery: Case Series and Review of Literature. Obesity Surgery 2010;20:1312–1315.PubMedCrossRef
13.
Metadata
Title
Ectopic Bone in the Abdominal Cavity: A Surgical Nightmare
Authors
Zachary Torgersen
Angela Osmolak
Jai Bikhchandani
Armour R. Forse
Publication date
01-09-2013
Publisher
Springer US
Published in
Journal of Gastrointestinal Surgery / Issue 9/2013
Print ISSN: 1091-255X
Electronic ISSN: 1873-4626
DOI
https://doi.org/10.1007/s11605-013-2228-z

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