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Journal of Gastrointestinal Surgery

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01-11-2011 | Original Article

Evaluation of Postoperative Pancreatic Fistula After Total Gastrectomy with D2 Lymphadenectomy by ISGPF Classification

Authors: Yuichiro Miki, Masanori Tokunaga, Etsuro Bando, Yutaka Tanizawa, Taiichi Kawamura, Masanori Terashima

Published in: Journal of Gastrointestinal Surgery | Issue 11/2011

Abstract

Introduction

Postoperative pancreatic fistula (POPF) is a serious complication of total gastrectomy (TG) with D2 lymphadenectomy (D2). However, the actual incidence and risk factors are not yet completely understood, due in part to the absence of the widely accepted criteria for POPF following gastrectomy.

Patients and methods

One hundred and four patients who underwent TG with D2 between March 2007 and December 2009 were included in this study. The incidence and severity of POPF were evaluated according to the International Study Group on Pancreatic Fistula (ISGPF) classification. In addition, risk factors for POPF of ISGPF grade B or higher were investigated.

Results

POPFs of ISGPF grade B or higher were observed in 23 patients (22.1%). Univariate analysis found that sex, body mass index, and amylase concentration of drainage fluid (d-AMY) on the first postoperative day (1POD) were significant predictors of POPF grade B or higher. The appropriate cutoff level of d-AMY on 1POD was calculated as 3398 IU/l. Multivariate analysis showed that d-AMY ≥3,398 IU/l on 1POD was the only independent risk factor.

Conclusions

High d-AMY on 1POD (≥3,398 IU/l) can predict a grade B or higher POPF, and this value may be useful in the early detection of POPF following TG with D2.

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Title: Evaluation of Postoperative Pancreatic Fistula After Total Gastrectomy with D2 Lymphadenectomy by ISGPF Classification
Authors: Yuichiro Miki
Masanori Tokunaga
Etsuro Bando
Yutaka Tanizawa
Taiichi Kawamura
Masanori Terashima
Publication date: 01-11-2011
Publisher: Springer-Verlag
Published in: Journal of Gastrointestinal Surgery / Issue 11/2011
Print ISSN: 1091-255X
Electronic ISSN: 1873-4626
DOI: https://doi.org/10.1007/s11605-011-1628-1

ACC 2024 Congress

Springer Medicine

Evaluation of Postoperative Pancreatic Fistula After Total Gastrectomy with D2 Lymphadenectomy by ISGPF Classification

Abstract

Introduction

Patients and methods

Results

Conclusions

ACC 2024 Congress

Springer Medicine

Abstract

Introduction

Patients and methods

Results

Conclusions

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