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01-03-2011 | Original Article

Computed Tomography Reflected Endocrine Function of the Pancreas

Authors: Naoaki Sakata, Shinichi Egawa, Toshiki Rikiyama, Gumpei Yoshimatsu, Kunihiro Masuda, Hideo Ohtsuka, Shigeru Ottomo, Kei Nakagawa, Hiroki Hayashi, Takanori Morikawa, Tohru Onogawa, Kuniharu Yamamoto, Hiroshi Yoshida, Masanori Akada, Fuyuhiko Motoi, Takeshi Naitoh, Yu Katayose, Michiaki Unno

Published in: Journal of Gastrointestinal Surgery | Issue 3/2011

Abstract

Backgrouns/Aims

There are few studies about the assessment of pancreatic function using computed tomography (CT) volumetry. In this study, we examined the correlation between CT volumetry and endocrine parameters (blood glucose and HbA1c) of the pancreas.

Methods

A total of 68 patients underwent enhanced CT for pancreatic disease from January to December in 2008. In particular, we analyzed the correlation of diabetic status and pancreatic CT parameters at 1 year after pancreatoduodenectomy in 32 patients. CT parameters including volume, volume/body weight, arterial phase density, the arterial phase to portal phase density ratio (A/P ratio) of the pancreas, and size of pancreatic duct were also analyzed. Correlation between CT parameters and diabetic status was analyzed preoperatively and postoperatively by ANOVA test.

Results

The preoperative diabetic status and parameters correlated well with arterial phase density (p = 0.004), A/P ratio, and pancreatic duct size (p < 0.0001). In the patients who underwent pancreatectomy, two out of 25 patients without preoperative diabetes mellitus (DM) had DM, and two out of seven patients with preoperative DM recovered from DM. Postoperative CT parameters correlated with the DM status 1 year after pancreatectomy.

Conclusion

CT is a useful modality for evaluation of the pancreatic endocrine function and could be used for the prediction of postoperative diabetic outcome.

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Title: Computed Tomography Reflected Endocrine Function of the Pancreas
Authors: Naoaki Sakata
Shinichi Egawa
Toshiki Rikiyama
Gumpei Yoshimatsu
Kunihiro Masuda
Hideo Ohtsuka
Shigeru Ottomo
Kei Nakagawa
Hiroki Hayashi
Takanori Morikawa
Tohru Onogawa
Kuniharu Yamamoto
Hiroshi Yoshida
Masanori Akada
Fuyuhiko Motoi
Takeshi Naitoh
Yu Katayose
Michiaki Unno
Publication date: 01-03-2011
Publisher: Springer-Verlag
Published in: Journal of Gastrointestinal Surgery / Issue 3/2011
Print ISSN: 1091-255X
Electronic ISSN: 1873-4626
DOI: https://doi.org/10.1007/s11605-010-1406-5

At a glance: The STEP trials

Springer Medicine

Computed Tomography Reflected Endocrine Function of the Pancreas

Abstract

Backgrouns/Aims

Methods

Results

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Backgrouns/Aims

Methods

Results

Conclusion

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