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Journal of Gastrointestinal Surgery

Published in:

01-01-2011 | Original Article

A Case–Control Study of Laparoscopy-Assisted and Open Distal Gastrectomy for Advanced Gastric Cancer

Authors: Jianbo Shuang, Shengbin Qi, Jianyong Zheng, Qinchuan Zhao, Jipeng Li, Zhenghua Kang, Jin Hua, Jianjun Du

Published in: Journal of Gastrointestinal Surgery | Issue 1/2011

Abstract

Background

The application of laparoscopy-assisted gastric surgery has been increasing rapidly for the treatment of early gastric cancer. However, there were few reports of laparoscopic surgery in the management of advanced gastric cancer (AGC), especially with T3 depth of invasion. The aim of this study was to compare the technical feasibility and oncologic efficacy of laparoscopy-assisted distal gastrectomy (LADG) versus open distal gastrectomy (ODG) for advanced gastric cancer.

Methods

A retrospective case–control study was performed comparing LADG and ODG for AGC. Thirty-five consecutive patients with AGC undergoing LADG between August 2005 and December 2007 were enrolled and these patients were compared with 35 AGC patients undergoing ODG during the same period.

Results

Forty-two (60.0%) patients were T3 in terms of depth of invasion. Tumor location and histology were similar between the two groups. Operation time was significantly longer in the LADG group than in the ODG group. Estimated blood loss was significantly less in the LADG group. Hospital length of stay after LADG was significantly shorter than in the open group. Postoperative pain was significantly lower for laparoscopic patients. There were no significant differences in postoperative early and late complication and in the number of lymph nodes retrieved between the two groups, and the cumulative survival of the two groups was similar.

Conclusion

Our data indicate that LADG for AGC, mostly with T3 depth of invasion, yields good oncologic outcomes including the similar early and late complication and the cumulative survival between the two groups after 50 months of follow-up. To be accepted as a choice treatment for advanced distal gastric cancer, well-designed prospective trial to assess long-term outcomes is necessary.

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Title: A Case–Control Study of Laparoscopy-Assisted and Open Distal Gastrectomy for Advanced Gastric Cancer
Authors: Jianbo Shuang
Shengbin Qi
Jianyong Zheng
Qinchuan Zhao
Jipeng Li
Zhenghua Kang
Jin Hua
Jianjun Du
Publication date: 01-01-2011
Publisher: Springer-Verlag
Published in: Journal of Gastrointestinal Surgery / Issue 1/2011
Print ISSN: 1091-255X
Electronic ISSN: 1873-4626
DOI: https://doi.org/10.1007/s11605-010-1361-1

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

A Case–Control Study of Laparoscopy-Assisted and Open Distal Gastrectomy for Advanced Gastric Cancer

Abstract

Background

Methods

Results

Conclusion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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