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01-12-2010 | Original Article

Simultaneous Liver and Colorectal Resections Are Safe for Synchronous Colorectal Liver Metastases

Authors: Yanxin Luo, Lei Wang, Chuangqi Chen, Dianke Chen, Meijin Huang, Yihua Huang, Junsheng Peng, Ping Lan, Ji Cui, Shirong Cai, Jianping Wang

Published in: Journal of Gastrointestinal Surgery | Issue 12/2010

Abstract

Background

Hepatic resection (HR) is the only option offering a potential cure for patients with synchronous colorectal cancer liver metastases (SCRLM). The optimal timing of HR for SCRLM is still controversial. This study aimed to determine whether simultaneous HR is similar to staged resection regarding the morbidity and mortality rates in patients with SCRLM.

Methods

Four hundred and five consecutive patients with SCRLM were treated with either simultaneous (n = 129) or staged (n = 276) HR. The postoperative complications were analyzed retrospectively according to the documented records and hepatectomy databases at the Gastrointestinal Institute.

Results

Perioperative morbidity and mortality did not differ between simultaneous resections and staged resections for selected patients with SCRLM (morbidity, 47.3% versus 54.3%; mortality, 1.5% versus 2.0%, respectively; both p > 0.05). Simultaneous liver resections of three or more segments would not increase the rate of complications compared to staged resections (56.8% and 42.4%, respectively; p = 0.119). Meanwhile, patients with simultaneous resections experienced shorter duration of surgery and postoperative hospitalization time as well as less blood loss during surgery (all p < 0.05).

Conclusions

Simultaneous resections of colorectal cancer primary lesions and hepatic metastases were safe and could serve as a primary option for selected SCRLM patients.

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Title: Simultaneous Liver and Colorectal Resections Are Safe for Synchronous Colorectal Liver Metastases
Authors: Yanxin Luo
Lei Wang
Chuangqi Chen
Dianke Chen
Meijin Huang
Yihua Huang
Junsheng Peng
Ping Lan
Ji Cui
Shirong Cai
Jianping Wang
Publication date: 01-12-2010
Publisher: Springer-Verlag
Published in: Journal of Gastrointestinal Surgery / Issue 12/2010
Print ISSN: 1091-255X
Electronic ISSN: 1873-4626
DOI: https://doi.org/10.1007/s11605-010-1284-x

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Simultaneous Liver and Colorectal Resections Are Safe for Synchronous Colorectal Liver Metastases

Abstract

Background

Methods

Results

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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