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Journal of Gastrointestinal Surgery

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01-02-2010 | DeMeester Feschrift

Emerging Concepts of Bile Reflux in the Constellation of Gastroesophageal Reflux Disease

Authors: Werner K. H. Kauer, Hubert J. Stein

Published in: Journal of Gastrointestinal Surgery | Special Issue 1/2010

Abstract

Rationale

Reflux of gastric and duodenal contents in patients with gastroesophageal reflux disease (GERD) has been postulated as a major cause of complications, such as Barrett’s esophagus or malignant degeneration.

Findings

We present a summary of experimental, clinical, and immunohistochemical studies that show that acid and bile reflux are increased in patients who suffer from GERD, are the key factor in the pathogenesis of Barrett’s esophagus, and are possibly related to the development of esophageal adenocarcinoma.

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Title: Emerging Concepts of Bile Reflux in the Constellation of Gastroesophageal Reflux Disease
Authors: Werner K. H. Kauer
Hubert J. Stein
Publication date: 01-02-2010
Publisher: Springer-Verlag
Published in: Journal of Gastrointestinal Surgery / Issue Special Issue 1/2010
Print ISSN: 1091-255X
Electronic ISSN: 1873-4626
DOI: https://doi.org/10.1007/s11605-009-1014-4

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Emerging Concepts of Bile Reflux in the Constellation of Gastroesophageal Reflux Disease

Abstract

Rationale

Findings

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Rationale

Findings

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