Skip to main content
Top
Published in: Journal of Gastrointestinal Surgery 5/2009

01-05-2009 | original article

Results of Completion Gastrectomies in 44 Patients with Postsurgical Gastric Atony

Authors: James E. Speicher, Richard C. Thirlby, Joseph Burggraaf, Christopher Kelly, Sarah Levasseur

Published in: Journal of Gastrointestinal Surgery | Issue 5/2009

Login to get access

Abstract

Introduction

Postsurgical gastric atony occurs infrequently after gastric surgery. However, the symptoms are disabling and refractory to medical management. The only effective treatment is completion gastrectomy. A few studies have examined in detail the long-term results of this radical procedure.

Methods

From 1988 through 2007, 44 patients (84% female, 16% male) underwent near-total or total completion gastrectomies for refractory postsurgical gastric atony. The average age was 52 (range 32–72). Gastric atony was documented using radionuclide solid food emptying studies. Charts were reviewed retrospectively to identify preoperative symptoms and long-term postoperative function, and the patients were contacted by phone to evaluate their current level of function.

Results

Of the original 44 patients, 66% (n = 29) were evaluated postoperatively at a mean of 5.6 + 4.5 years (range 0.5–15.0 years). Fourteen patients (32%) had died, and seven (16%) were lost to follow-up. Most common presenting symptoms were abdominal pain (98%), vomiting (98%), nausea (77%), diet limitation (75%), heartburn (64%), and weight loss (59%, average = 19% of BW). Postoperative complications occurred in 36% (n = 16), most commonly bowel obstruction (11%), anastomotic stricture (9%), and anastomotic leak (7%), and there was one perioperative death. At last follow-up, there were significant improvements in abdominal pain (97% to 59%, p < 0.001), vomiting (97% to 31%, p < 0.001), nausea (86% to 45%, p < 0.001), and diet limited to liquids or nothing at all (57% to 7%, p < 0.001). Some symptoms were more common postoperatively, including early satiety (24% to 89%, p < 0.001), and postprandial fullness (10% to 72%, p < 0.001). Average BMI at the time of surgery and at last follow-up were 23 and 21, respectively. Osteoporosis was diagnosed pre- and postoperatively in 17% and 67% of patients, respectively (p < 0.001). Seventy-eight percent of patients stated that they were in better health after surgery, while 17% were neutral, and 6% stated that they were worse off. Mean satisfaction with surgery was 4.7 (1–5 Likert scale).

Conclusion

Completion gastrectomies in this patient population resulted in significant improvements in abdominal pain, vomiting, nausea, and severe diet limitations. Most patients, however, have significant ongoing gastrointestinal complaints, and the incidence of osteoporosis is high. Patient satisfaction is high; about 78% of patients believed their health status is improved. We believe these data support the selective use of completion gastrectomies in patients with severe postsurgical gastroparesis.
Literature
2.
go back to reference Schirmer BD. Gastric atony and the Roux syndrome. Gastroenterol Clin North Am 1994;23:327–343.PubMed Schirmer BD. Gastric atony and the Roux syndrome. Gastroenterol Clin North Am 1994;23:327–343.PubMed
4.
go back to reference Dong K, Li B, Guan QL, Huang T. Analysis of multiple factors of postsurgical gastroparesis syndrome after pancreaticoduodenectomy and cryotherapy for pancreatic cancer. World J Gastroenterol 2004;10:2434–2438.PubMed Dong K, Li B, Guan QL, Huang T. Analysis of multiple factors of postsurgical gastroparesis syndrome after pancreaticoduodenectomy and cryotherapy for pancreatic cancer. World J Gastroenterol 2004;10:2434–2438.PubMed
5.
go back to reference Azpiroz F, Malagelada JR. Gastric tone measured by an electronic barostat in health and postsurgical gastroparesis. Gastroenterology 1987;92:934–943.PubMed Azpiroz F, Malagelada JR. Gastric tone measured by an electronic barostat in health and postsurgical gastroparesis. Gastroenterology 1987;92:934–943.PubMed
6.
go back to reference Eckhauser FE, Conrad M, Knol JA, Mulholland MW, Colletti LM. Safety and long-term durability of completion gastrectomy in 81 patients with postsurgical gastroparesis syndrome. Am Surg 1998;64:711–716.PubMed Eckhauser FE, Conrad M, Knol JA, Mulholland MW, Colletti LM. Safety and long-term durability of completion gastrectomy in 81 patients with postsurgical gastroparesis syndrome. Am Surg 1998;64:711–716.PubMed
7.
go back to reference Hirao M, Fujitani K, Tsujinaka T. Delayed gastric emptying after distal gastrectomy for gastric cancer. Hepatogastroenterology 2005;52:305–309.PubMed Hirao M, Fujitani K, Tsujinaka T. Delayed gastric emptying after distal gastrectomy for gastric cancer. Hepatogastroenterology 2005;52:305–309.PubMed
11.
go back to reference Patterson DJ. Prokinetic agents in postgastrectomy patients. Gastroenterol Clin North Am 1994;23:313–325.PubMed Patterson DJ. Prokinetic agents in postgastrectomy patients. Gastroenterol Clin North Am 1994;23:313–325.PubMed
12.
go back to reference Forstner-Barthell AW, Murr MM, Nitecki S, Camilleri M, Prather CM, Kelly KA, Sarr MG. Near-total completion gastrectomy for severe postvagotomy gastric stasis: analysis of early and long-term results in 62 patients. J Gastrointest Surg 1999;3:15–21. discussion doi:10.1016/S1091-255X(99)80003-1.PubMedCrossRef Forstner-Barthell AW, Murr MM, Nitecki S, Camilleri M, Prather CM, Kelly KA, Sarr MG. Near-total completion gastrectomy for severe postvagotomy gastric stasis: analysis of early and long-term results in 62 patients. J Gastrointest Surg 1999;3:15–21. discussion doi:10.​1016/​S1091-255X(99)80003-1.PubMedCrossRef
17.
go back to reference McCallum RW, Polepalle SC, Schirmer B. Completion gastrectomy for refractory gastroparesis following surgery for peptic ulcer disease. Long-term follow-up with subjective and objective parameters. Dig Dis Sci 1991;36:1556–1561. doi:10.1007/BF01296397.PubMedCrossRef McCallum RW, Polepalle SC, Schirmer B. Completion gastrectomy for refractory gastroparesis following surgery for peptic ulcer disease. Long-term follow-up with subjective and objective parameters. Dig Dis Sci 1991;36:1556–1561. doi:10.​1007/​BF01296397.PubMedCrossRef
18.
go back to reference Hinder RA, Esser J, DeMeester TR. Management of gastric emptying disorders following the Roux-en-Y procedure. Surgery 1988;104:765–772.PubMed Hinder RA, Esser J, DeMeester TR. Management of gastric emptying disorders following the Roux-en-Y procedure. Surgery 1988;104:765–772.PubMed
20.
go back to reference Gustavsson S, Kelly KA. Total gastrectomy for benign disease. Surg Clin North Am 1987;67:539–550.PubMed Gustavsson S, Kelly KA. Total gastrectomy for benign disease. Surg Clin North Am 1987;67:539–550.PubMed
21.
go back to reference Bradshaw BGG, Thirlby RC. The value of sham-feeding tests in patients with post-gastrectomy syndromes. Arch Surg 1993;128:982–987.PubMed Bradshaw BGG, Thirlby RC. The value of sham-feeding tests in patients with post-gastrectomy syndromes. Arch Surg 1993;128:982–987.PubMed
22.
go back to reference Meyer JH. Nutritional outcomes of gastric operations. Gastroenterol Clin North Am 1994;23:227–260.PubMed Meyer JH. Nutritional outcomes of gastric operations. Gastroenterol Clin North Am 1994;23:227–260.PubMed
23.
go back to reference Pol B, LeTreut YP, Hardwigsen J, Rosset E, Houvenaeghel G, Delpero JR. Mechanically stapled esophagojejunostomy. Results of a prospective series of 176 cases. Hepatogastroenterology 1997;44:458–466.PubMed Pol B, LeTreut YP, Hardwigsen J, Rosset E, Houvenaeghel G, Delpero JR. Mechanically stapled esophagojejunostomy. Results of a prospective series of 176 cases. Hepatogastroenterology 1997;44:458–466.PubMed
24.
go back to reference Viste A, Eide GE, Soreide O. Stomach cancer: a prospective study of anastomotic failure following total gastrectomy. Acta Chir Scand 1987;153:303–306.PubMed Viste A, Eide GE, Soreide O. Stomach cancer: a prospective study of anastomotic failure following total gastrectomy. Acta Chir Scand 1987;153:303–306.PubMed
26.
go back to reference Agaba EA, Shamseddeen H, Gentles CV, Sasthakonar V, Gellman L, Gadaleta D. Laparoscopic vs open gastric bypass in the management of morbid obesity: a 7-year retrospective study of 1,364 patients from a single center. Obes Surg 2008;18:1359–1363. doi:10.1007/s11695-008-9455-5.PubMedCrossRef Agaba EA, Shamseddeen H, Gentles CV, Sasthakonar V, Gellman L, Gadaleta D. Laparoscopic vs open gastric bypass in the management of morbid obesity: a 7-year retrospective study of 1,364 patients from a single center. Obes Surg 2008;18:1359–1363. doi:10.​1007/​s11695-008-9455-5.PubMedCrossRef
27.
go back to reference Jones KB Jr, Afram JD, Benotti PN, Capella RF, Cooper CG, Flanagan L, Hendrick S, Howell LM, Jaroch MT, Kole K, Lirio OC, Sapala JA, Schuhknecht MP, Shapiro RP, Sweet WA, Wood MH. Open versus laparoscopic Roux-en-Y gastric bypass: a comparative study of over 25,000 open cases and the major laparoscopic bariatric reported series. Obes Surg 2006;16:721–727. doi:10.1381/096089206777346628.PubMedCrossRef Jones KB Jr, Afram JD, Benotti PN, Capella RF, Cooper CG, Flanagan L, Hendrick S, Howell LM, Jaroch MT, Kole K, Lirio OC, Sapala JA, Schuhknecht MP, Shapiro RP, Sweet WA, Wood MH. Open versus laparoscopic Roux-en-Y gastric bypass: a comparative study of over 25,000 open cases and the major laparoscopic bariatric reported series. Obes Surg 2006;16:721–727. doi:10.​1381/​0960892067773466​28.PubMedCrossRef
29.
go back to reference Ely JJ. Inadequate levels of essential nutrients in developed nations as a risk factor for disease: a review. Rev Environ Health 2003;18:111–129.PubMed Ely JJ. Inadequate levels of essential nutrients in developed nations as a risk factor for disease: a review. Rev Environ Health 2003;18:111–129.PubMed
Metadata
Title
Results of Completion Gastrectomies in 44 Patients with Postsurgical Gastric Atony
Authors
James E. Speicher
Richard C. Thirlby
Joseph Burggraaf
Christopher Kelly
Sarah Levasseur
Publication date
01-05-2009
Publisher
Springer-Verlag
Published in
Journal of Gastrointestinal Surgery / Issue 5/2009
Print ISSN: 1091-255X
Electronic ISSN: 1873-4626
DOI
https://doi.org/10.1007/s11605-009-0821-y

Other articles of this Issue 5/2009

Journal of Gastrointestinal Surgery 5/2009 Go to the issue