Skip to main content
Top
Published in: Journal of Gastrointestinal Surgery 1/2009

01-01-2009 | original article

The Spectrum of Abdominal Tuberculosis in a Developed Country: A Single Institution’s Experience Over 7 Years

Authors: Ker-Kan Tan, Kenneth Chen, Richard Sim

Published in: Journal of Gastrointestinal Surgery | Issue 1/2009

Login to get access

Abstract

Background

The incidence of human immunodeficiency virus (HIV) infection is rising, and as a result, tuberculosis (TB) has become a resurgent problem in many developed countries.

Objectives

The aim of this study was to review the spectrum of abdominal TB and its surgical management in our institution.

Methods

A retrospective review of all abdominal TB cases notified to the health authorities by our institution from Jan 01 to Oct 07 was performed.

Results

There were 57 patients (37 men) with abdominal TB, with a median age of 47 (range 14–74) years. Active pulmonary TB was present in 27 patients (47%). Positive HIV status was present in 30% and untested in 58%. The majority of patients underwent computed tomography scans (n = 50, 88%). The main radiological findings included bowel thickening, lymphadenopathy, ascites, free gas suggestive of perforation, and abscesses. The diagnosis of TB was confirmed on microbiological and/or histological examination in 72%, while the remaining 28% were diagnosed based on the clinical presentation and radiological imaging. All patients were commenced on anti-tuberculous therapy. TB involved the small or large bowel in 33 patients, mesenteric lymphadenopathy in 24, peritoneum in 13, spleen in seven, pancreas in two, anus in two, and the liver in two. Disseminated (including pulmonary) TB occurred in 27 patients (47%), while isolated intra-abdominal TB occurred in the remaining 30 patients (53%). Twenty-five patients (44%) underwent surgery—16 laparotomies (six perforated viscus, five intestinal obstruction, three suspected malignancies, and two for suspected acute abdomen), five laparoscopic procedures (four diagnostic, one gastrojejunostomy bypass for gastric outlet obstruction), two appendicectomies, one drainage of abscess, and one anal fistulotomy.

Conclusions

Although TB is eminently treatable medically, surgery is still often required for suspected or confirmed abdominal TB presenting with acute complications or as atypical diagnostic problems. The role of laparoscopy is likely to be more significant in future in the management of abdominal TB.
Literature
4.
go back to reference Uygur-Bayramicli O, Dabak G, Dabak R. A clinical dilemma: abdominal tuberculosis. World J Gastroenterol 2003;9(5):1098–1101.PubMed Uygur-Bayramicli O, Dabak G, Dabak R. A clinical dilemma: abdominal tuberculosis. World J Gastroenterol 2003;9(5):1098–1101.PubMed
6.
go back to reference Jadvar H, Mindelzun RE, Olcott EW, Levitt DB. Still the great mimicker: abdominal tuberculosis. Am J Roentgenol 1997;168:1455–1460. Jadvar H, Mindelzun RE, Olcott EW, Levitt DB. Still the great mimicker: abdominal tuberculosis. Am J Roentgenol 1997;168:1455–1460.
8.
go back to reference Uzunkoy A, Harma M, Harma M. Diagnosis of abdominal tuberculosis: experience from 11 cases and review of the literature. World J Gastroenterol 2004;10(24):3647–3649.PubMed Uzunkoy A, Harma M, Harma M. Diagnosis of abdominal tuberculosis: experience from 11 cases and review of the literature. World J Gastroenterol 2004;10(24):3647–3649.PubMed
9.
go back to reference Kapoor VK. Abdominal tuberculosis. Postgrad Med J 1998;74(874):459–467.PubMed Kapoor VK. Abdominal tuberculosis. Postgrad Med J 1998;74(874):459–467.PubMed
10.
go back to reference Leder RA, Low VH. Tuberculosis of the abdomen. Radiol Clin North Am 1995;33:691–705.PubMed Leder RA, Low VH. Tuberculosis of the abdomen. Radiol Clin North Am 1995;33:691–705.PubMed
11.
go back to reference Suri S, Gupta S, Suri R. Computed tomography in abdominal tuberculosis. Br J Radiol 1999;72:92–98.PubMed Suri S, Gupta S, Suri R. Computed tomography in abdominal tuberculosis. Br J Radiol 1999;72:92–98.PubMed
12.
go back to reference Demirkazik FB, Akhan O, Ozmen MN, Akata D. US and CT findings in the diagnosis of tuberculous peritonitis. Acta Radiol 1996;37:517–520.PubMedCrossRef Demirkazik FB, Akhan O, Ozmen MN, Akata D. US and CT findings in the diagnosis of tuberculous peritonitis. Acta Radiol 1996;37:517–520.PubMedCrossRef
13.
go back to reference Balthazar EJ, Gordon R, Hulnick D. Ileocecal tuberculosis: CT and radiologic evaluation. Am J Roentgenol 1990;154:499–503. Balthazar EJ, Gordon R, Hulnick D. Ileocecal tuberculosis: CT and radiologic evaluation. Am J Roentgenol 1990;154:499–503.
15.
go back to reference Range N, Ipuge YA, O’Brien RJ, Egwaga SM, Mfinanga SG, Chonde TM et al. Trend in HIV prevalence among tuberculosis patients in Tanzania, 1991–1998. Int J Tuberc Lung Dis 2001;5(5):405–412.PubMed Range N, Ipuge YA, O’Brien RJ, Egwaga SM, Mfinanga SG, Chonde TM et al. Trend in HIV prevalence among tuberculosis patients in Tanzania, 1991–1998. Int J Tuberc Lung Dis 2001;5(5):405–412.PubMed
16.
go back to reference Centers for Disease Control and Prevention (CDC). Reported HIV status of tuberculosis patients—United States, 1993–2005. MMWR Morb Mortal Wkly Rep 2007;56(42):1103–1106. Centers for Disease Control and Prevention (CDC). Reported HIV status of tuberculosis patients—United States, 1993–2005. MMWR Morb Mortal Wkly Rep 2007;56(42):1103–1106.
21.
go back to reference Muga R, Ferreros I, Langohr K, de Olalla PG, Del Romero J, Quintana M, Spanish Multicenter Study Group of Seroconverters (GEMES) et al. Changes in the incidence of tuberculosis in a cohort of HIV-seroconverters before and after the introduction of HAART. AIDS 2007;21(18):2521–2527.PubMedCrossRef Muga R, Ferreros I, Langohr K, de Olalla PG, Del Romero J, Quintana M, Spanish Multicenter Study Group of Seroconverters (GEMES) et al. Changes in the incidence of tuberculosis in a cohort of HIV-seroconverters before and after the introduction of HAART. AIDS 2007;21(18):2521–2527.PubMedCrossRef
22.
go back to reference Elliott AM, Halwiindi B, Hayes RJ, Luo N, Mwinga AG, Tembo G et al. The impact of human immunodeficiency virus on response to treatment and recurrence rate in patients treated for tuberculosis: two-year follow-up of a cohort in Lusaka, Zambia. J Trop Med Hyg 1995;98(1):9–21.PubMed Elliott AM, Halwiindi B, Hayes RJ, Luo N, Mwinga AG, Tembo G et al. The impact of human immunodeficiency virus on response to treatment and recurrence rate in patients treated for tuberculosis: two-year follow-up of a cohort in Lusaka, Zambia. J Trop Med Hyg 1995;98(1):9–21.PubMed
23.
go back to reference Chau TN, Leung VK, Wong S, Law ST, Chan WH, Luk IS et al. Diagnostic challenges of tuberculosis peritonitis in patients with and without end-stage renal failure. Clin Infect Dis 2007;45(12):141–146. doi:10.1086/523727.CrossRef Chau TN, Leung VK, Wong S, Law ST, Chan WH, Luk IS et al. Diagnostic challenges of tuberculosis peritonitis in patients with and without end-stage renal failure. Clin Infect Dis 2007;45(12):141–146. doi:10.​1086/​523727.CrossRef
24.
go back to reference Malik GH, Al-Harbi AS, Al-Mohaya S, Al-Khawajah H, Kechrid M, Al Hassan AO et al. Eleven years of experience with dialysis associated tuberculosis. Clin Nephrol 2002;58(5):356–362.PubMed Malik GH, Al-Harbi AS, Al-Mohaya S, Al-Khawajah H, Kechrid M, Al Hassan AO et al. Eleven years of experience with dialysis associated tuberculosis. Clin Nephrol 2002;58(5):356–362.PubMed
26.
go back to reference McGee GS, Lester WF, Potts J et al. Gastrointestinal tuberculosis resurgence of an old pathogen. Am Surg 1989;55:16–19.PubMed McGee GS, Lester WF, Potts J et al. Gastrointestinal tuberculosis resurgence of an old pathogen. Am Surg 1989;55:16–19.PubMed
31.
go back to reference Isaacs P, Zissis M. Colonic tuberculosis and adenocarcinoma: an unusual presentation. Eur J Gastroenterol Hepatol 1997;9(9):913–915.PubMed Isaacs P, Zissis M. Colonic tuberculosis and adenocarcinoma: an unusual presentation. Eur J Gastroenterol Hepatol 1997;9(9):913–915.PubMed
32.
go back to reference Kaushik R, Sharma R, Attri AK. Coexisting tuberculosis and carcinoma of the colon: a report of two cases and a review of the literature. Trop Gastroenterol 2003;24(3):137–139.PubMed Kaushik R, Sharma R, Attri AK. Coexisting tuberculosis and carcinoma of the colon: a report of two cases and a review of the literature. Trop Gastroenterol 2003;24(3):137–139.PubMed
34.
go back to reference Weissman D, Gumaste VV, Dave PB, Keh W. Bleeding from a tuberculous gastric ulcer. Am J Gastroenterol 1990;85(6):742–744.PubMed Weissman D, Gumaste VV, Dave PB, Keh W. Bleeding from a tuberculous gastric ulcer. Am J Gastroenterol 1990;85(6):742–744.PubMed
35.
go back to reference Sahoo D, Mahapatra MK, Salim S. Rectal tuberculosis: a rare case. Trop Gastroenterol 2004;25(2):84–85.PubMed Sahoo D, Mahapatra MK, Salim S. Rectal tuberculosis: a rare case. Trop Gastroenterol 2004;25(2):84–85.PubMed
36.
go back to reference Monkemuller KE, Lewis JB Jr. Massive rectal bleeding from colonic tuberculosis. Am J Gastroenterol 1996;91(7):1439–1441.PubMed Monkemuller KE, Lewis JB Jr. Massive rectal bleeding from colonic tuberculosis. Am J Gastroenterol 1996;91(7):1439–1441.PubMed
38.
go back to reference Claro I, Leitão CN, Oliveira P, Correia J, da Costa JD, Almeida JM et al. Tuberculous mesenteric lymphadenitis mimicking pancreatic carcinoma. Hepatogastroenterology 1996;43(12):1653–1655.PubMed Claro I, Leitão CN, Oliveira P, Correia J, da Costa JD, Almeida JM et al. Tuberculous mesenteric lymphadenitis mimicking pancreatic carcinoma. Hepatogastroenterology 1996;43(12):1653–1655.PubMed
39.
go back to reference Kim YS, Moon JS, Lee JW, Kim I, Ryu SH, Paik IW. Solitary intra-abdominal tuberculous lymphadenopathy mimicking duodenal GIST. Korean J Intern Med 2005;20(1):72–75.PubMed Kim YS, Moon JS, Lee JW, Kim I, Ryu SH, Paik IW. Solitary intra-abdominal tuberculous lymphadenopathy mimicking duodenal GIST. Korean J Intern Med 2005;20(1):72–75.PubMed
40.
go back to reference Brookes MJ, Field M, Dawkins DM, Gearty J, Wilson P. Massive primary hepatic tuberculoma mimicking hepatocellular carcinoma in an immunocompetent host. Med Gen Med 2006;8(3):11. Brookes MJ, Field M, Dawkins DM, Gearty J, Wilson P. Massive primary hepatic tuberculoma mimicking hepatocellular carcinoma in an immunocompetent host. Med Gen Med 2006;8(3):11.
42.
go back to reference Vanhoenacker FM, De Backer AI, Op DB et al. Imaging of gastrointestinal and abdominal tuberculosis. Eur Radiol 2004;14:103–115. Vanhoenacker FM, De Backer AI, Op DB et al. Imaging of gastrointestinal and abdominal tuberculosis. Eur Radiol 2004;14:103–115.
43.
go back to reference Klimach OE, Ormerod LP. Gastrointestinal tuberculosis: a retrospective review of 109 cases in a district general hospital. Q J Med 1985;56:569–578.PubMed Klimach OE, Ormerod LP. Gastrointestinal tuberculosis: a retrospective review of 109 cases in a district general hospital. Q J Med 1985;56:569–578.PubMed
45.
go back to reference Gilinsky NH, Marks IN, Kottler RE et al. Abdominal tuberculosis: a 10-year review. S Afr Med J 1983;64:849–857.PubMed Gilinsky NH, Marks IN, Kottler RE et al. Abdominal tuberculosis: a 10-year review. S Afr Med J 1983;64:849–857.PubMed
47.
51.
go back to reference Al Quorain AA, Satti MB, al Gindan YM, al Ghassab GA, al Freihi HM. Tuberculous peritonitis: the value of laparoscopy. Hepatogastroenterology 1991;38:37–40.PubMed Al Quorain AA, Satti MB, al Gindan YM, al Ghassab GA, al Freihi HM. Tuberculous peritonitis: the value of laparoscopy. Hepatogastroenterology 1991;38:37–40.PubMed
53.
go back to reference Schippers E, Tittel A, Ottinger A, Schumpelick V. Laparoscopy versus laparotomy: comparison of adhesion formation after bowel resection in a canine model. Dig Surg 1998;15:145–147. doi:10.1159/000018608.PubMedCrossRef Schippers E, Tittel A, Ottinger A, Schumpelick V. Laparoscopy versus laparotomy: comparison of adhesion formation after bowel resection in a canine model. Dig Surg 1998;15:145–147. doi:10.​1159/​000018608.PubMedCrossRef
Metadata
Title
The Spectrum of Abdominal Tuberculosis in a Developed Country: A Single Institution’s Experience Over 7 Years
Authors
Ker-Kan Tan
Kenneth Chen
Richard Sim
Publication date
01-01-2009
Publisher
Springer-Verlag
Published in
Journal of Gastrointestinal Surgery / Issue 1/2009
Print ISSN: 1091-255X
Electronic ISSN: 1873-4626
DOI
https://doi.org/10.1007/s11605-008-0669-6

Other articles of this Issue 1/2009

Journal of Gastrointestinal Surgery 1/2009 Go to the issue

ssat other

Aviation