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Japanese Journal of Radiology
Published in: Japanese Journal of Radiology 9/2018

01-09-2018 | Original Article

Simple quantification of paracardial and epicardial fat dimensions at low-dose chest CT: correlation with metabolic risk factors and usefulness in predicting metabolic syndrome

Authors: Chaehun Lim, Myeong-Im Ahn, Jung Im Jung, Kyongmin Sarah Beck

Published in: Japanese Journal of Radiology | Issue 9/2018

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Abstract

Purpose

To assess the usefulness of simple axial bi-dimensional diameters of pericardial fat tissues at low-dose chest CT, in correlation with metabolic parameters in predicting metabolic syndrome.

Materials and methods

Subjects were 373 asymptomatic individuals who performed both low-dose chest CT and abdominal fat CT for medical check-up. Maximum bi-dimensional axial diameters of paracardial fats at right (RPF) and left (LPF) cardiophrenic angle portions, and epicardial fats around right (REF) and left (LEF) coronary arteries, and coronary sinus (SEF) were measured. Correlation between pericardial fat diameters and metabolic parameters were statistically analyzed.

Results

RPF, LPF, REF, LEF, and SEF diameters were moderately correlated with abdominal visceral fat (AVF) area (R = 0.74, 0.70, 0.48, 0.41, and 0.53, respectively, p < 0.01) in Pearson’s correlation analysis. In multiple linear regression analysis, coefficient of RPF for AVF showed highest value. Means of each PF and EF diameters in subjects with metabolic syndrome were significantly larger than those without metabolic syndrome (p < 0.001). All PF and EF diameters were well-discriminated for prediction of metabolic syndrome in ROC analysis (AUC values, from 0.696 to 0.795).

Conclusion

RPF diameter at low-dose chest CT would be a simple method for prediction of metabolic syndrome.
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Metadata
Title
Simple quantification of paracardial and epicardial fat dimensions at low-dose chest CT: correlation with metabolic risk factors and usefulness in predicting metabolic syndrome
Authors
Chaehun Lim
Myeong-Im Ahn
Jung Im Jung
Kyongmin Sarah Beck
Publication date
01-09-2018
Publisher
Springer Japan
Published in
Japanese Journal of Radiology / Issue 9/2018
Print ISSN: 1867-1071
Electronic ISSN: 1867-108X
DOI
https://doi.org/10.1007/s11604-018-0752-1

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