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01-04-2018 | Invited Review

Pathology and images of radiation-induced hepatitis: a review article

Authors: Shigeyuki Takamatsu, Kazuto Kozaka, Satoshi Kobayashi, Norihide Yoneda, Kotaro Yoshida, Dai Inoue, Azusa Kitao, Takahiro Ogi, Tetsuya Minami, Wataru Kouda, Tomoyasu Kumano, Nobukazu Fuwa, Osamu Matsui, Toshifumi Gabata

Published in: Japanese Journal of Radiology | Issue 4/2018

Abstract

Recent advances in highly conformal radiotherapies greatly extend the indications for radiotherapy of liver tumors. However, because of poor tolerance to hepatic radiation, estimation of the intensity of irradiation of the liver is important, particularly for a cirrhotic liver. Knowledge of radiation-induced hepatitis is important for understanding how to optimize hepatic radiation therapy. Pathological changes of the irradiated liver, which include perivenular fibrosis, sinusoidal obstruction, and damage to Kupffer cells and hepatocytes, can be visualized using clinical imaging techniques. This review article discusses and illustrates the pathological and radiological changes of hepatic tumors and the surrounding parenchyma of the irradiated liver.

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Title: Pathology and images of radiation-induced hepatitis: a review article
Authors: Shigeyuki Takamatsu
Kazuto Kozaka
Satoshi Kobayashi
Norihide Yoneda
Kotaro Yoshida
Dai Inoue
Azusa Kitao
Takahiro Ogi
Tetsuya Minami
Wataru Kouda
Tomoyasu Kumano
Nobukazu Fuwa
Osamu Matsui
Toshifumi Gabata
Publication date: 01-04-2018
Publisher: Springer Japan
Published in: Japanese Journal of Radiology / Issue 4/2018
Print ISSN: 1867-1071
Electronic ISSN: 1867-108X
DOI: https://doi.org/10.1007/s11604-018-0728-1

At a glance: The ONWARDS insulin icodec trials

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Pathology and images of radiation-induced hepatitis: a review article

Abstract

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