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Published in: Japanese Journal of Radiology 2/2018

01-02-2018 | Technical Note

Four-dimensional cone-beam computed tomography-guided radiotherapy for gastric lymphoma

Authors: Ryo Toya, Tetsuo Saito, Yoshinobu Shimohigashi, Yohei Yotsuji, Tomohiko Matsuyama, Takahiro Watakabe, Yudai Kai, Yasuyuki Yamashita, Natsuo Oya

Published in: Japanese Journal of Radiology | Issue 2/2018

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Abstract

Purpose

We describe a treatment method with four-dimensional cone-beam computed tomography (4D-CBCT)-guided radiotherapy for gastric lymphoma.

Materials and methods

We performed image-guided radiotherapy (IGRT) with 15 fractions for a gastric mucosa-associated lymphoid tissue lymphoma patient, using 4D-CBCT. The stomach was delineated based on 4D-CT images. For image guidance, an automatic registration between planning CT and 4D-CBCT images was performed based on the bony anatomy (bone matching), followed by manual registration based on the stomach in 4D-CBCT images of all 10 phases (4D matching). We calculated the covering ratio (CR) with variable stomach-to-planning target volume (PTV) margins, based on the images of all phases [CR (%) = the number of covering phases/all 150 phases × 100].

Results

The patient underwent radiotherapy (RT) as scheduled, without any significant adverse effects. The appropriate PTV margins (CR ≥ 95%) were 25 mm (CR 99.3%) and 15 mm (CR 98.7%) for bone and 4D matching, respectively.

Conclusion

4D matching using 4D-CBCT is appropriate for IGRT of gastric lymphomas.
Literature
1.
go back to reference Shimohigashi Y, Toya R, Saito T, Ikeda O, Maruyama M, Yonemura K, et al. Tumor motion changes in stereotactic body radiotherapy for liver tumors: an evaluation based on four-dimensional cone-beam computed tomography and fiducial markers. Radiat Oncol. 2017;12:61.CrossRefPubMedPubMedCentral Shimohigashi Y, Toya R, Saito T, Ikeda O, Maruyama M, Yonemura K, et al. Tumor motion changes in stereotactic body radiotherapy for liver tumors: an evaluation based on four-dimensional cone-beam computed tomography and fiducial markers. Radiat Oncol. 2017;12:61.CrossRefPubMedPubMedCentral
2.
go back to reference Matoba M, Oota K, Toyoda I, Kitadate M, Watanabe N, Tonami H. Usefulness of 4D-CT for radiation treatment planning of gastric MZBCL/MALT. J Radiat Res. 2012;53:333–7.CrossRefPubMed Matoba M, Oota K, Toyoda I, Kitadate M, Watanabe N, Tonami H. Usefulness of 4D-CT for radiation treatment planning of gastric MZBCL/MALT. J Radiat Res. 2012;53:333–7.CrossRefPubMed
3.
go back to reference Johnson ME, Pereira GC, El Naqa IM, Goddu SM, Al-Lozi R, Apte A, et al. Determination of planning target volume for whole stomach irradiation using daily megavoltage computed tomographic images. Pract Radiat Oncol. 2012;2:e85–8.CrossRefPubMed Johnson ME, Pereira GC, El Naqa IM, Goddu SM, Al-Lozi R, Apte A, et al. Determination of planning target volume for whole stomach irradiation using daily megavoltage computed tomographic images. Pract Radiat Oncol. 2012;2:e85–8.CrossRefPubMed
4.
go back to reference Castro FA, Jansen L, Krilaviciute A, Katalinic A, Pulte D, Sirri E, et al. Survival of patients with gastric lymphoma in Germany and in the United States. J Gastroenterol Hepatol. 2015;30:1485–91.CrossRefPubMed Castro FA, Jansen L, Krilaviciute A, Katalinic A, Pulte D, Sirri E, et al. Survival of patients with gastric lymphoma in Germany and in the United States. J Gastroenterol Hepatol. 2015;30:1485–91.CrossRefPubMed
5.
go back to reference Yahalom J, Illidge T, Specht L, Hoppe RT, Li YX, Tsang R, et al. Modern radiation therapy for extranodal lymphomas: field and dose guidelines from the International Lymphoma Radiation Oncology Group. Int J Radiat Oncol Biol Phys. 2015;92:11–31.CrossRefPubMed Yahalom J, Illidge T, Specht L, Hoppe RT, Li YX, Tsang R, et al. Modern radiation therapy for extranodal lymphomas: field and dose guidelines from the International Lymphoma Radiation Oncology Group. Int J Radiat Oncol Biol Phys. 2015;92:11–31.CrossRefPubMed
6.
go back to reference Koch P, Probst A, Berdel WE, Willich NA, Reinartz G, Brockmann J, et al. Treatment results in localized primary gastric lymphoma: data of patients registered within the German multicenter study (GIT NHL 02/96). J Clin Oncol. 2005;23:7050–9.CrossRefPubMed Koch P, Probst A, Berdel WE, Willich NA, Reinartz G, Brockmann J, et al. Treatment results in localized primary gastric lymphoma: data of patients registered within the German multicenter study (GIT NHL 02/96). J Clin Oncol. 2005;23:7050–9.CrossRefPubMed
7.
go back to reference Schechter NR, Portlock CS, Yahalom J. Treatment of mucosa-associated lymphoid tissue lymphoma of the stomach with radiation alone. J Clin Oncol. 1998;16:1916–21.CrossRefPubMed Schechter NR, Portlock CS, Yahalom J. Treatment of mucosa-associated lymphoid tissue lymphoma of the stomach with radiation alone. J Clin Oncol. 1998;16:1916–21.CrossRefPubMed
8.
go back to reference Inaba K, Okamoto H, Wakita A, Nakamura S, Kobayashi K, Harada K, et al. Radiotherapy for gastric lymphoma: a planning study of 3D conformal radiotherapy, the half-beam method, and intensity-modulated radiotherapy. J Radiat Res. 2014;55:1141–5.CrossRefPubMedPubMedCentral Inaba K, Okamoto H, Wakita A, Nakamura S, Kobayashi K, Harada K, et al. Radiotherapy for gastric lymphoma: a planning study of 3D conformal radiotherapy, the half-beam method, and intensity-modulated radiotherapy. J Radiat Res. 2014;55:1141–5.CrossRefPubMedPubMedCentral
Metadata
Title
Four-dimensional cone-beam computed tomography-guided radiotherapy for gastric lymphoma
Authors
Ryo Toya
Tetsuo Saito
Yoshinobu Shimohigashi
Yohei Yotsuji
Tomohiko Matsuyama
Takahiro Watakabe
Yudai Kai
Yasuyuki Yamashita
Natsuo Oya
Publication date
01-02-2018
Publisher
Springer Japan
Published in
Japanese Journal of Radiology / Issue 2/2018
Print ISSN: 1867-1071
Electronic ISSN: 1867-108X
DOI
https://doi.org/10.1007/s11604-017-0698-8

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