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01-12-2017 | Technical Note

Preliminary results of a new workflow for MRI/CT-based image-guided brachytherapy in cervical carcinoma

Authors: Miho Watanabe Nemoto, Yuma Iwai, Gentaro Togasaki, Marie Kurokawa, Rintarou Harada, Hiroki Kobayashi, Takashi Uno

Published in: Japanese Journal of Radiology | Issue 12/2017

Abstract

Purpose

We propose a method of image-guided brachytherapy (IGBT) that combines MRI-based target volume delineation for the first fraction with CT datasets of subsequent fractions, using an automatic, applicator-based co-registration, and report our preliminary experience.

Materials and methods

The MRI of the first fraction was used for the first brachytherapy planning. For each subsequent brachytherapy fraction, after the same applicator insertion, a new CT scan with the applicator in place was obtained. The MR image set was registered to the subsequent brachytherapy treatment planning CT using the applicator for rigid body registration. To demonstrate the registration quality, we used here the Dice index as a measurement of tandem delineation overlap between CT and MRI.

Results

The median Dice index was 0.879 (range 0.610–0.932), which indicated that the contours on CT and MRI fitted well. With this combination method, the median D90 of HR CTV and the calculated D2 cm³ of the bladder, rectum, and sigmoid in each fraction were 7.2 (4.0–10.4), 5.9 (2.3–7.7), 4.0 (1.9–6.7), and 3.8 (0.6–7.2) Gy, respectively.

Conclusion

Our described method of MRI-guided IGBT offers a practical option for the benefits of target delineation.

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Title: Preliminary results of a new workflow for MRI/CT-based image-guided brachytherapy in cervical carcinoma
Authors: Miho Watanabe Nemoto
Yuma Iwai
Gentaro Togasaki
Marie Kurokawa
Rintarou Harada
Hiroki Kobayashi
Takashi Uno
Publication date: 01-12-2017
Publisher: Springer Japan
Published in: Japanese Journal of Radiology / Issue 12/2017
Print ISSN: 1867-1071
Electronic ISSN: 1867-108X
DOI: https://doi.org/10.1007/s11604-017-0690-3

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Springer Medicine

Preliminary results of a new workflow for MRI/CT-based image-guided brachytherapy in cervical carcinoma

Abstract

Purpose

Materials and methods

Results

Conclusion

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Abstract

Purpose

Materials and methods

Results

Conclusion

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