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Japanese Journal of Radiology
Published in: Japanese Journal of Radiology 8/2017

01-08-2017 | Original Article

Coronary computed tomography angiography using 128-slice dual-source computed tomography in patients with severe calcification

Authors: Suguru Sato, Yosuke Horii, Norihiko Yoshimura, Takuya Yagi, Hidefumi Aoyama

Published in: Japanese Journal of Radiology | Issue 8/2017

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Abstract

Purpose

To compare coronary computed tomography angiography (CTA) and coronary angiography (CAG) with regard to luminal graphic definition of calcified segments using 128-slice dual-source computed tomography (DSCT), specifically for patients with an Agatston score >400.

Materials and methods

Of 1148 consecutive patients who underwent coronary CTA using a 128-slice DSCT, 132 subjects had severe calcification with an Agatston score >400. Thirty-nine of the 132 patients who had undergone CAG within 3 months before or after coronary CTA were included. We investigated the distribution of calcification, and we visually evaluated significant stenosis in the calcified and all segments. Results were compared with CAG.

Results

The target group in this study had a very high mean Agatston score of 1771 ± 1724. Results for sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of 247 calcified vs all 325 segments were as follows: sensitivity 93.2 vs 92.2%, specificity 83.9 vs 87.5%, PPV 70.8 vs 69.6%, and NPV 96.7 vs 97.3%, respectively.

Conclusion

128-slice DSCT has potential for evaluation of calcified segments in the lumen, even in patients whose Agatston score exceeds 400.
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Metadata
Title
Coronary computed tomography angiography using 128-slice dual-source computed tomography in patients with severe calcification
Authors
Suguru Sato
Yosuke Horii
Norihiko Yoshimura
Takuya Yagi
Hidefumi Aoyama
Publication date
01-08-2017
Publisher
Springer Japan
Published in
Japanese Journal of Radiology / Issue 8/2017
Print ISSN: 1867-1071
Electronic ISSN: 1867-108X
DOI
https://doi.org/10.1007/s11604-017-0650-y

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