Published in:
01-07-2017 | Letter to the Editor
Utility of MR imaging in the evaluation of colon cancer: emphasis on distinguishing tumor tissue from fibrosis and role of contrast media
Authors:
Akitoshi Inoue, Shinichi Ohta, Norihisa Nitta, Masahiro Yoshimura, Tomoharu Shimizu, Masaji Tani, Ryoji Kushima, Kiyoshi Murata
Published in:
Japanese Journal of Radiology
|
Issue 7/2017
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Excerpt
We appreciate the interest of Sivrioglu et al. in our article [
1]. The peritumoral fibrosis is known as a desmoplastic reaction. It is a state of increasing fibroblasts and myofibroblasts in the interstitium with tumor invasion. The linear architecture of the fat indicated a desmoplastic reaction and T3 tumor in our study, but it was observed in one patient with T2 tumor [
2]. This fibrosis results in overdiagnosis in T staging. Earlier research stated a speculation that perirectal fat represented a T2 tumor, whereas another one suggested an early T3 tumor. It is important and difficult to distinguish tumor invasion from fibrosis for accurate T staging, especially in discriminating a T2 (limited within the colon wall) from a T3 tumor (beyond the colon wall). …
