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Published in: Japanese Journal of Radiology 1/2017

01-01-2017 | Original Article

Is it essential to use fiducial markers during cone-beam CT-based radiotherapy for prostate cancer patients?

Authors: Berna A. Yildirim, Cem Onal, Yemliha Dolek

Published in: Japanese Journal of Radiology | Issue 1/2017

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Abstract

Purpose

To compare soft-tissue cone-beam computed tomography (CBCT-P) and fiducial marker (CBCT-FM)-based image guided radiotherapy in prostate cancer patients.

Materials and methods

Sixteen prostate cancer patients were treated with volumetric modulated arc therapy. Manual alignment using CBCT-P and CBCT-FM was performed for each patient. Couch shifts were calculated and compared between methods in the left–right (x), superior–inferior (y), and anterior–posterior (z) directions.

Results

CBCT-P and CBCT-FM alignments were compared using 252 scans from the 16 patients. Mean displacement from zero was 2.4 ± 1.3, 1.7 ± 1.2, and 1.8 ± 1.1 mm for CBCT-P and 2.3 ± 1.3, 1.7 ± 1.1 and 1.8 ± 1.1 mm for CBCT-FM in the x, y and z directions, respectively. There was no difference in median displacement between CBCT-P and CBCT-FM; however, there was a significant positive correlation between CBCT-P- and CBCT-FM-based displacements in the x (r = 0.881; p < 0.001), y (r = 0.789; p < 0.001) and z (r = 0.856; p < 0.001) directions by linear regression analysis. Systematic deviations within each group were <1 mm; however, random and systematic errors were similar in the x and y directions but larger in the z direction.

Conclusion

Our study demonstrated that CBCT-FM was not superior to CBCT-P for image-guided radiotherapy in prostate cancer patients.
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Metadata
Title
Is it essential to use fiducial markers during cone-beam CT-based radiotherapy for prostate cancer patients?
Authors
Berna A. Yildirim
Cem Onal
Yemliha Dolek
Publication date
01-01-2017
Publisher
Springer Japan
Published in
Japanese Journal of Radiology / Issue 1/2017
Print ISSN: 1867-1071
Electronic ISSN: 1867-108X
DOI
https://doi.org/10.1007/s11604-016-0590-y

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