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Japanese Journal of Radiology
Published in: Japanese Journal of Radiology 5/2015

01-05-2015 | Original Article

The incidence of contrast medium-induced nephropathy following endovascular aortic aneurysm repair: assessment of risk factors

Authors: Serkan Guneyli, Halil Bozkaya, Celal Cinar, Mehmet Korkmaz, Soner Duman, Turker Acar, Yigit Akin, Mustafa Parildar, Ismail Oran

Published in: Japanese Journal of Radiology | Issue 5/2015

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Abstract

Purpose

The aim of the study was to investigate the incidence of contrast medium-induced nephropathy (CIN) and risk factors for CIN following endovascular abdominal aortic aneurysm repair or thoracic endovascular aortic aneurysm repair.

Materials and methods

After exclusion criteria, 139 (121 males, 18 females) patients aged 20–86 (median 65.5) years who underwent endovascular aortic aneurysm repair between January 2002 and September 2013 were included in this retrospective study. CIN, with ≥25 % increase in serum creatinine levels within 3 days after contrast medium administration, was compared to the patients’ demographics, risk factors, type and complexity of the endovascular operation, parameters regarding to the contrast medium, preoperative estimated glomerular filtration rate (eGFR), and preoperative and early postoperative serum parameters. Statistical analyses were performed with Kolmogorov-Smirnov, χ 2 and Student’s t tests.

Results

CIN, detected in 39 of 139 patients (28 %), was correlated with preoperative eGFR <60 ml/min/1.73 m2 (P = 0.04) and high preoperative and postoperative serum urea and creatinine levels. Postoperative serum urea levels (P < 0.001) were significant in multivariate analysis.

Conclusion

In patients undergoing endovascular aortic aneurysm repair, CIN was correlated with preoperative and postoperative renal impairment, while it was not correlated with the contrast medium dose.
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Metadata
Title
The incidence of contrast medium-induced nephropathy following endovascular aortic aneurysm repair: assessment of risk factors
Authors
Serkan Guneyli
Halil Bozkaya
Celal Cinar
Mehmet Korkmaz
Soner Duman
Turker Acar
Yigit Akin
Mustafa Parildar
Ismail Oran
Publication date
01-05-2015
Publisher
Springer Japan
Published in
Japanese Journal of Radiology / Issue 5/2015
Print ISSN: 1867-1071
Electronic ISSN: 1867-108X
DOI
https://doi.org/10.1007/s11604-015-0408-3

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