Skip to main content
Top
Published in: HAND 1/2009

01-03-2009

Delayed Neuropathy Due to Organophosphate Insecticide Injection in an Attempt to Commit Suicide

Authors: Selma Sönmez Ergün, Kahraman Öztürk, Özlem Su, Esra Başar Gürsoy, Işıl Uğurad, Gökşen Yüksel

Published in: HAND | Issue 1/2009

Login to get access

Abstract

Organophosphates (OPs) are commonly used as pesticides throughout the world. Exposures to OPs cause a significant number of poisonings and deaths every year. Organophosphate-induced delayed polyneuropathy is a sensory-motor distal axonopathy which usually occurs after exposure of certain OP insecticides. Neuropathies due to ingestion of OPs have rarely been reported in the literature. Moreover, until now, there is no report of a patient developing organophosphorus injection-induced delayed neuropathy in the literature. We report a patient with serious organophosphorus-induced delayed neuropathy due to malathion injection. The patient was a 32-year-old female who self-injected undetermined amounts of malathion over the median nerve trace on the forearm crease in a suicide attempt which resulted in peripheral neuropathy.
Literature
1.
go back to reference Brannagan TH III, Weimer LH, Latov N. Acquired neuropathies. In: Rowland LP, editor. Merritt’s neurology. 11th ed. New York: Lippincot Williams & Wilkins; 2005. p. 748–67. Brannagan TH III, Weimer LH, Latov N. Acquired neuropathies. In: Rowland LP, editor. Merritt’s neurology. 11th ed. New York: Lippincot Williams & Wilkins; 2005. p. 748–67.
2.
go back to reference Caroldi S, Lotti M, Masutti A. Intra-arterial injection of diisopropylfluorophoshate or phenylmethanesulphonyl fluoride produces unilateral neuropathy or protection, respectively, in hens. Biochem Pharmacol. 1984;33(20):3213–7. doi:10.1016/0006-2952(84)90079-0.PubMedCrossRef Caroldi S, Lotti M, Masutti A. Intra-arterial injection of diisopropylfluorophoshate or phenylmethanesulphonyl fluoride produces unilateral neuropathy or protection, respectively, in hens. Biochem Pharmacol. 1984;33(20):3213–7. doi:10.​1016/​0006-2952(84)90079-0.PubMedCrossRef
3.
go back to reference Frykman GK, Wolf A, Coyle T. An algorithm for management of peripheral nerve injuries. Orthop Clin North Am. 1981;12(2):239–44.PubMed Frykman GK, Wolf A, Coyle T. An algorithm for management of peripheral nerve injuries. Orthop Clin North Am. 1981;12(2):239–44.PubMed
4.
go back to reference Gentili F, Hudson AR, Hunter D. Clinical and experimental aspects of injection injuries of peripheral nerves. Can J Neurol Sci. 1980;7(2):143–51.PubMed Gentili F, Hudson AR, Hunter D. Clinical and experimental aspects of injection injuries of peripheral nerves. Can J Neurol Sci. 1980;7(2):143–51.PubMed
7.
go back to reference Gutowski KA. Peripheral nerves and tendon transfers. In: Hand II. Selected Readings in Plastic Surgery; 2003;9(33). p. 1–55. Gutowski KA. Peripheral nerves and tendon transfers. In: Hand II. Selected Readings in Plastic Surgery; 2003;9(33). p. 1–55.
8.
go back to reference Hadimioğlu N, Dosemeci L, Arici G, Ramazanoglu A. Systemic organophosphate poisoning following the percutaneous injection of insecticide. Case report. Skin Pharmacol Appl Skin Physiol. 2002;15(3):195–9. doi:10.1159/000063548.PubMedCrossRef Hadimioğlu N, Dosemeci L, Arici G, Ramazanoglu A. Systemic organophosphate poisoning following the percutaneous injection of insecticide. Case report. Skin Pharmacol Appl Skin Physiol. 2002;15(3):195–9. doi:10.​1159/​000063548.PubMedCrossRef
9.
go back to reference Latov N. General considerations. In: Rowland LP, editor. Merritt’s neurology. 11th ed. New York: Lippincot Williams & Wilkins; 2005. p. 735–7. Latov N. General considerations. In: Rowland LP, editor. Merritt’s neurology. 11th ed. New York: Lippincot Williams & Wilkins; 2005. p. 735–7.
10.
go back to reference Lotti M, Moretto A. Organophosphate-induced delayed polyneuropathy. Toxicol Rev. 2005;24(1):37–49.PubMedCrossRef Lotti M, Moretto A. Organophosphate-induced delayed polyneuropathy. Toxicol Rev. 2005;24(1):37–49.PubMedCrossRef
12.
go back to reference Moretto A, Lotti M. Poisoning by organophosphorus insecticides and sensory neuropathy. J Neurosurg Psychiatry. 1998;64(4):463–8.CrossRef Moretto A, Lotti M. Poisoning by organophosphorus insecticides and sensory neuropathy. J Neurosurg Psychiatry. 1998;64(4):463–8.CrossRef
14.
go back to reference Omer GE. Timing of tendon transfers in peripheral nerve injury. Hand Clin. 1988;4(2):317–22. Review, May.PubMed Omer GE. Timing of tendon transfers in peripheral nerve injury. Hand Clin. 1988;4(2):317–22. Review, May.PubMed
15.
Metadata
Title
Delayed Neuropathy Due to Organophosphate Insecticide Injection in an Attempt to Commit Suicide
Authors
Selma Sönmez Ergün
Kahraman Öztürk
Özlem Su
Esra Başar Gürsoy
Işıl Uğurad
Gökşen Yüksel
Publication date
01-03-2009
Publisher
Springer-Verlag
Published in
HAND / Issue 1/2009
Print ISSN: 1558-9447
Electronic ISSN: 1558-9455
DOI
https://doi.org/10.1007/s11552-008-9126-y

Other articles of this Issue 1/2009

HAND 1/2009 Go to the issue