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International Journal of Computer Assisted Radiology and Surgery

Published in:

01-04-2017 | Original Article

Computer-assisted delineation of cerebral infarct from diffusion-weighted MRI using Gaussian mixture model

Authors: Manas Kumar Nag, Subhranil Koley, Debarghya China, Anup Kumar Sadhu, Ravikanth Balaji, Siddharth Ghosh, Chandan Chakraborty

Published in: International Journal of Computer Assisted Radiology and Surgery | Issue 4/2017

Abstract

Purpose

Diffusion-weighted imaging (DWI) is a widely used medical imaging modality for diagnosis and monitoring of cerebral stroke. The identification of exact location of stroke lesion helps in perceiving its characteristics, an essential part of diagnosis and treatment planning. This task is challenging due to the typical shape of the stroke lesion. This paper proposes an efficient method for computer-aided delineation of stroke lesions from DWI images.

Method

Proposed methodology comprises of three steps. At the initial step, image contrast has been improved by applying fuzzy intensifier leading to the better visual quality of the stroke lesion. In the following step, a two-class (stroke lesion area vs. non-stroke lesion area) segmentation technique based on Gaussian mixture model has been designed for the localization of stroke lesion. To eliminate the artifacts which would appear during segmentation process, a binary morphological post-processing through area operator has been defined for exact delineation of the lesion area.

Result

The performance of the proposed methodology has been compared with the manually delineated images (ground truth) obtained from different experts, individually. Quantitative evaluation with respect to various performance measures (such as dice coefficient, Jaccard score, and correlation coefficient) shows the efficient performance of the proposed technique.

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Title: Computer-assisted delineation of cerebral infarct from diffusion-weighted MRI using Gaussian mixture model
Authors: Manas Kumar Nag
Subhranil Koley
Debarghya China
Anup Kumar Sadhu
Ravikanth Balaji
Siddharth Ghosh
Chandan Chakraborty
Publication date: 01-04-2017
Publisher: Springer International Publishing
Published in: International Journal of Computer Assisted Radiology and Surgery / Issue 4/2017
Print ISSN: 1861-6410
Electronic ISSN: 1861-6429
DOI: https://doi.org/10.1007/s11548-017-1520-x

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Computer-assisted delineation of cerebral infarct from diffusion-weighted MRI using Gaussian mixture model

Abstract

Purpose

Method

Result

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Purpose

Method

Result

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