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01-02-2012 | HSS OSTEOARTHRITIS SYMPOSIUM: FRONTIERS IN OA

Articular Cartilage Degradation in Osteoarthritis

Author: Mary B. Goldring, PhD

Published in: HSS Journal ® | Issue 1/2012

Excerpt

The composition and cellular organization of human adult articular cartilage are complex with qualitative and quantitative differences in matrix constituents ranging from the superficial through deep zones and between the interterritorial and territorial, or pericellular, regions. Chondrocytes, the unique cellular component of articular cartilage, maintain the matrix components under normal, low turnover conditions in which the glycosaminoglycans on proteoglycans and other noncollagen molecules can be replaced. The pericellular matrix is also important, with constituents such as collagen VI, fibromodulin, and matrilin 3, but little or no type II collagen. …

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Title: Articular Cartilage Degradation in Osteoarthritis
Author: Mary B. Goldring, PhD
Publication date: 01-02-2012
Publisher: Springer-Verlag
Published in: HSS Journal ® / Issue 1/2012
Print ISSN: 1556-3316
Electronic ISSN: 1556-3324
DOI: https://doi.org/10.1007/s11420-011-9250-z

At a glance: The STEP trials

Springer Medicine

Articular Cartilage Degradation in Osteoarthritis

Excerpt

At a glance: The STEP trials

Springer Medicine

Excerpt

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