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Published in: HSS Journal ® 1/2012

01-02-2012 | HSS OSTEOARTHRITIS SYMPOSIUM: FRONTIERS IN OA

Osteoarthritis as a Whole Joint Disease

Author: A. Robin Poole, PhD, DSc

Published in: HSS Journal ® | Issue 1/2012

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Excerpt

Osteoarthritis (OA) is a disease that causes pain and disability. It is usually slowly progressive, and cartilage degeneration with a loss of joint space (a common measure of progression) is often not continuous, as evidenced by numerous clinical trials and longitudinal studies. The emphasis of research and clinical trials has been on the degeneration of articular cartilage, being required with synovial fluid for the almost frictionless articulation and a key determinant, with the meniscus, of knee joint space on radiographic analysis. However, emerging evidence exists that all or almost all joint tissues are involved and/or affected by this degenerative process (Fig. 1).
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Metadata
Title
Osteoarthritis as a Whole Joint Disease
Author
A. Robin Poole, PhD, DSc
Publication date
01-02-2012
Publisher
Springer-Verlag
Published in
HSS Journal ® / Issue 1/2012
Print ISSN: 1556-3316
Electronic ISSN: 1556-3324
DOI
https://doi.org/10.1007/s11420-011-9248-6

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