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Forensic Toxicology

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01-07-2020 | Dihydrocodeine | Letter to the Editor

Drug levels in fatal cases where death was not directly attributable to drug toxicity

Authors: Kerryanne Shearer, Julie McAdam, Michael Parsons

Published in: Forensic Toxicology | Issue 2/2020

Excerpt

Dear Editor, …

Scottish government (2020) Alcohol and drugs. https://www.gov.scot/policies/alcohol-and-drugs/. Accessed 18 Feb 2020

Koski A, Ojanperä I, Vuori E (2003) Interaction of alcohol and drugs in fatal poisonings. Hum Exp Toxicol 22:281–287. https://doi.org/10.1191/0960327103ht324oa CrossRefPubMed

Kaye S, Haag HB (1957) Terminal blood alcohol concentrations in ninety-four fatal cases of acute alcoholism. JAMA 165:451–452. https://doi.org/10.1001/jama.1957.7298023000106 CrossRef

Pharmacy Times (2007) Top 200 brand-name drugs by units in 2006: drug topics (March 5, 2007). https://www.pharmacytimes.com/publications/issue/2007/2007-05/2007-05-6472.. Accessed 19 Feb 2020

BoryBorys DJ, Setzer SC, Ling LJ, Reisdorf JJ, Day LC, Krenzelok EP (1992) Acute fluoxetine overdose: a report of 234 cases. Am J Emerg Med 10:115–120. https://doi.org/10.1016/0735-6757(92)90041-u CrossRef

Goeringer KE, Raymon L, Christian GD, Logan BK (2000) Post mortem forensic toxicology of selective serotonin reuptake inhibitors: a review of pharmacology and report of 168 cases. J Forensic Sci 45:633–648 (PMID: 10855970)PubMed

Finkle BS, McCloskey KL, Goodman LS (1979) Diazepam and drug-associated deaths. JAMA 242:429–434 (PMID: 448958)CrossRef

Dinovo EC, Gottschalk LA, McGuire FL, Birch H, Heiser JF (1976) Analysis of results of toxicological examination performed by the coroners’ or medical examiners’ laboratories in 2000 drug-involved deaths in nine major US cities. Clin Chem 22:847–850. https://doi.org/10.1093/clinchem/22.6.847 CrossRefPubMed

Reynolds JEF (ed) (1996) Martindale. The extra pharmacopeia, 31st edn. The Pharmaceutical Press, London

10.

Paterson SC (1985) Drug levels found in cases of fatal self-poisoning. Forensic Sci Int 27:129–133. https://doi.org/10.1016/0379-0738(85)90175-6 CrossRefPubMed

11.

Peat MA, Sengupta A (1997) Toxicological investigations of cases of death involving codeine and dihydrocodeine. Forensic Sci 9:21–32. https://doi.org/10.1016/0300-9432(77)90061-9 CrossRef

12.

Raida J (1994) Drogentodesfälle durch dihydrocodeinhaltige Ersatzmittel. Dtsch Ärtzebl 91:A-1303

13.

Drummer OH (2004) Postmortem toxicology of drugs of abuse. Forensic Sci Int 142:101–113. https://doi.org/10.1016/j.forsciint.2004.02.013 CrossRefPubMed

14.

Logan BK, Oliver JS, Smith H (1987) The measurement and interpretation of morphine in blood. Forensic Sci Int 35:189–195. https://doi.org/10.1016/0379-0738(87)90055-7 CrossRefPubMed

15.

Felby S, Christiansen H, Lund A (1974) Morphine concentrations in blood and organs in cases of fatal poisoning. Forensic Sci 3:77–81. https://doi.org/10.1016/0300-94 CrossRefPubMed

16.

Moffat AC (ed) (1986) Clarkes isolation and identification of drugs. The Pharmaceutical Press, London

17.

Augsburger M, Donzé N, Ménétrey A, Brossard C, Sporkert F, Giroud C, Mangin P (2005) Concentration of drugs in blood of suspected impaired drivers. Forensic Sci Int 153:11–15. https://doi.org/10.1016/j.forsciint.2005.04.025 CrossRefPubMed

18.

Seymour A, Oliver JS (1999) Role of drugs and alcohol in impaired drivers and fatally injured drivers in the Strathclyde police region of Scotland 1995–1998. Forensic Sci Int 103:89–100. https://doi.org/10.1016/s0379-0738(99)00061-4 CrossRefPubMed

19.

Green M, Luke J, DuPont R (1974) Opiate overdose deaths in the district of Columbia. Part II. Methadone related fatality. J Forensic Sci 19:575–584. https://doi.org/10.1520/JFS10214J CrossRef

20.

Worm K, Steentoft A, Kringsholm B (1993) Methadone and drug addicts. Int J Legal Med 106:119–123. https://doi.org/10.1007/BF01225230 CrossRefPubMed

21.

Gagajewski A, Apple FS (2003) Methadone-related deaths in Hennepin County, Minnesota: 1992–2002. J Forensic Sci 48:668–671. https://doi.org/10.1520/JFS2002424 CrossRefPubMed

22.

Verschraagen M, Maes A, Ruiter B, Bosman IJ, Smink BE, Lusthof KJ (2007) Post-mortem cases involving amphetamine-based drugs in the Netherlands: comparison with driving under the influence cases. Forensic Sci Int 170:163–170. https://doi.org/10.1016/j.forsciint.2007.03.030 CrossRefPubMed

23.

Logan BK, Fligner CL, Haddix T (1998) Cause and manner of death in fatalities involving methamphetamine. J Forensic Sci 43:28–34. https://doi.org/10.1520/JFS16085J CrossRefPubMed

24.

Spiehler V, Reed D (1985) Brain concentrations of cocaine and benzoylecgonine in fatal cases. J Forensic Sci 30:1003–1011. https://doi.org/10.1520/JFS11042J CrossRefPubMed

25.

Dowling GP, McDonough ET 3rd, Bost RO (1987) ‘Eve’ and ‘Ecstasy’, a report of five deaths associated with the use of MDEA and MDMA. JAMA 257:1615–1617. https://doi.org/10.1001/jama.257.12.1615 CrossRefPubMed

26.

Henry JA, Jeffreys KJ, Dawling S (1992) Toxicity and deaths from 3,4-methylenedioxymethamphetamine (“ecstasy”). Lancet 340:384–387. https://doi.org/10.1016/0140-6736(92)91469-O CrossRefPubMed

27.

Baselt RC (2008) Disposition of toxic drugs and chemical in man, 8th edn. Biomedical Publications, Foster City

28.

Kelly CA, Dhaun N, Laing WJ, Strachan FE, Good AM, Batman DN (2004) Comparative toxicity of citalopram and the newer antidepressants after overdose. J Toxicol Clin Toxicol 42:67–71. https://doi.org/10.1081/CLT-120028747 CrossRefPubMed

29.

Anastos N, McIntyre IM, Lynch MJ, Drummer OH (2002) Postmortem concentrations of citalopram. J Forensic Sci 47:882–884. https://doi.org/10.1520/JFS15458J CrossRefPubMed

30.

Darke S, Torok M, Duflou J (2013) Contributory and incidental blood concentrations in deaths involving citalopram. J Forensic Sci 58:432–435. https://doi.org/10.1111/1556-4029.12046 CrossRefPubMed

Title: Drug levels in fatal cases where death was not directly attributable to drug toxicity
Authors: Kerryanne Shearer
Julie McAdam
Michael Parsons
Publication date: 01-07-2020
Publisher: Springer Singapore
Keywords: Dihydrocodeine
Morphine
Methadone
Citalopram
Fluoxetine
Diazepam
Published in: Forensic Toxicology / Issue 2/2020
Print ISSN: 1860-8965
Electronic ISSN: 1860-8973
DOI: https://doi.org/10.1007/s11419-020-00533-y

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