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Journal of Natural Medicines
Published in: Journal of Natural Medicines 1/2017

01-01-2017 | Original Paper

Evaluation of the chemical quality of Sekkoku (石斛) in current Japanese commercial crude drugs: constituents of Flickingeria xantholeuca (Rchb. f.) A.D. Hawkes

Authors: Mei Muto, Haruka Asahina, Tatsufumi Yoshioka, Kazuo Ozaki, Makio Shibano

Published in: Journal of Natural Medicines | Issue 1/2017

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Abstract

In our investigation, most Shihu (石斛; Japanese name, Sekkoku) in current Japanese commercial crude drugs were from Flickingeria xantholeuca (Orchidaceae). As the index compounds, three new ent-pimarane-type diterpenes, flickinxthanthosides A–C (1–3), one known analogue (7), and three new ent-kaurane-type diterpenes, flickinxanthosides D (4) and E (5) and flickinxanthol A (6) were isolated from the stem of F. xantholeuca. The structures of the new compounds were elucidated on the basis of spectroscopic analyses and chemical methods. We attempted to detect these index compounds from the MeOH extracts of other Dendrobium or Flickingeria plants using TLC and LC/MS.
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Metadata
Title
Evaluation of the chemical quality of Sekkoku (石斛) in current Japanese commercial crude drugs: constituents of Flickingeria xantholeuca (Rchb. f.) A.D. Hawkes
Authors
Mei Muto
Haruka Asahina
Tatsufumi Yoshioka
Kazuo Ozaki
Makio Shibano
Publication date
01-01-2017
Publisher
Springer Japan
Published in
Journal of Natural Medicines / Issue 1/2017
Print ISSN: 1340-3443
Electronic ISSN: 1861-0293
DOI
https://doi.org/10.1007/s11418-016-1054-5

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