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Sport Sciences for Health
Published in: Sport Sciences for Health 4/2021

01-12-2021 | COVID-19 | Review

Potential role of Nigella sativa supplementation with physical activity in prophylaxis and treatment of COVID-19: a contemporary review

Authors: Hossein Shirvani, Fatemeh Rostamkhani, Ehsan Arabzadeh, Faezeh Mohammadi, Fatemeh Mohammadi

Published in: Sport Sciences for Health | Issue 4/2021

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Abstract

The widespread prevalence and mortality of coronavirus diseases-2019 (COVID-19) lead many researchers to study the SARS-CoV-s2 infection to find a treatment for this disease. Discovering the mechanisms of action of COVID-19 and coping at the cellular level with this disease can have better effects. Including the target tissues of this disease are the lungs and the immune system. It is stated that COVID-19 easily infiltrates into alveoli through its receptors and then starts to proliferate. Subsequently, with the weakening of immune cells and increase inflammatory cytokines, it increases the rate of inflammation in the body. Strengthening the immune system and inhibiting COVID-19 receptors can play a preventive or even therapeutic role for this disease. Nigella sativa (N. sativa) is one of the herbal medicines to possess numerous pharmacological effects related to several organs of the body. Among the extraordinary properties of this plant is improving asthma and several lung diseases. The recent studies have shown that N. sativa at the cellular level can inhibit COVID-19 receptors. It was also stated that performing regular exercise training (especially moderate-intensity exercise training) can modulate the immune system and have an anti-inflammatory effect. Since the use of herbal supplements with exercise can have tremendous therapeutic effects at the cellular level, the hypothesis to use the Nigella sativa along with exercise training to prophylaxis and treatment COVID-19 will be highlighted in this paper.
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Metadata
Title
Potential role of Nigella sativa supplementation with physical activity in prophylaxis and treatment of COVID-19: a contemporary review
Authors
Hossein Shirvani
Fatemeh Rostamkhani
Ehsan Arabzadeh
Faezeh Mohammadi
Fatemeh Mohammadi
Publication date
01-12-2021
Publisher
Springer Milan
Published in
Sport Sciences for Health / Issue 4/2021
Print ISSN: 1824-7490
Electronic ISSN: 1825-1234
DOI
https://doi.org/10.1007/s11332-021-00787-y

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