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Oral Radiology
Published in: Oral Radiology 3/2021

01-07-2021 | Case Report

Ghost cell odontogenic carcinoma arising in the background of a calcifying odontogenic cyst

Authors: Chané Nel, Liam Robinson, Willie F. P. van Heerden

Published in: Oral Radiology | Issue 3/2021

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Abstract

Ghost cell odontogenic carcinoma (GCOC) is a rare malignant neoplasm, representing 3% of all ghost cell lesions of the jaws. They can arise de novo or from a pre-existing calcifying odontogenic cyst (COC) or dentinogenic ghost cell tumour (DGCT). A systematic review of the literature reported only 12 cases of a GCOC arising from a pre-existing COC. This report highlights an additional case of a GCOC arising from a pre-existing COC after 3 years in an adolescent male. The patient initially presented with a painless swelling of the right mandibular corpus. Panoramic radiographic examination showed an expansive unilocular radiolucent lesion. After 3 years, the radiographic features appeared more aggressive with increased expansion and cortical perforation. A wide surgical resection was performed, whereby the lesion was diagnosed as a GCOC. Due to the rarity of these malignant neoplasms, limited information is available regarding their biological behaviour. One-year follow-up revealed no clinical signs of recurrence.
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Metadata
Title
Ghost cell odontogenic carcinoma arising in the background of a calcifying odontogenic cyst
Authors
Chané Nel
Liam Robinson
Willie F. P. van Heerden
Publication date
01-07-2021
Publisher
Springer Singapore
Published in
Oral Radiology / Issue 3/2021
Print ISSN: 0911-6028
Electronic ISSN: 1613-9674
DOI
https://doi.org/10.1007/s11282-020-00492-5

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