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Oral Radiology
Published in: Oral Radiology 2/2020

01-04-2020 | Digital Volume Tomography | Original Article

Accuracy of ITK-SNAP software for 3D analysis of a non-regular topography structure

Authors: Amanda Farias Gomes, Danieli Moura Brasil, Amaro Ilídio Vespasiano Silva, Deborah Queiroz Freitas, Francisco Haiter-Neto, Francisco Carlos Groppo

Published in: Oral Radiology | Issue 2/2020

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Abstract

Objectives

To evaluate the accuracy of ITK-SNAP software for measuring volumes of a non-regular shape structure, using cone beam computed tomography (CBCT) scans, besides for developing a mathematical model to correct the software measurement error in case it existed.

Methods

A phantom made by moulding a rubber duck’s head was filled with total (38,000 mm3) and partial volumes of water (7000 mm3, 14,000 mm3, 21,000 mm3, 28,000 mm3 and 35,000 mm3), which constituted the gold standards. The sound phantom and the phantom filled with different volumes of water were scanned in a Picasso Trio CBCT unit set at 80 kVp, 3.7 mA, 0.2 mm3 voxel and 12 × 8.5 cm field of view. Semi-automatic segmentation was performed with ITK-SNAP 3.0 software by two trained oral radiologists. Linear regression analyzed the relation between ITK-SNAP calculated volumes and the gold standard. Intraclass correlation coefficient was applied to analyze the reproducibility of the method. Significance level was set at 5%.

Results

Linear regression analysis showed a significant relationship between ITK-SNAP volumes and the gold standard (F = 22,537.3, p < 0.0001), with an R2 of 0.9993. The average error found was 4.7 (± 4.3) %. To minimize this error, a mathematical model was developed and provided a reduction of it. ICC revealed excellent intra-examiner agreements for both examiners 1 (ICC = 0.9991, p < 0.0001) and 2 (ICC = 0.9989, p < 0.0001). Likewise, inter-examiner agreement was excellent (ICC = 0.9991, p < 0.0001).

Conclusion

The software showed to be accurate for evaluating non-regular shape structures. The mathematical model developed reduced an already small error on the software’s measurements.
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Metadata
Title
Accuracy of ITK-SNAP software for 3D analysis of a non-regular topography structure
Authors
Amanda Farias Gomes
Danieli Moura Brasil
Amaro Ilídio Vespasiano Silva
Deborah Queiroz Freitas
Francisco Haiter-Neto
Francisco Carlos Groppo
Publication date
01-04-2020
Publisher
Springer Singapore
Published in
Oral Radiology / Issue 2/2020
Print ISSN: 0911-6028
Electronic ISSN: 1613-9674
DOI
https://doi.org/10.1007/s11282-019-00397-y

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