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01-05-2017 | Original Article

Estimation of prognosis of tongue cancer using tumor depth and margin shape obtained from ultrasonography

Authors: Sitti Fadhillah Oemar Mattalitti, Toshiyuki Kawazu, Shintaro Kawano, Tatsuya Ikari, Hiroko Wada, Kazunori Yoshiura

Published in: Oral Radiology | Issue 2/2017

Abstract

Objectives

To evaluate the feasibility of using ultrasound-obtained tumor depth (TD) and margin shape (MS) to predict the prognosis of tongue cancer.

Methods

Fifty-two Japanese patients with tongue cancer who underwent ultrasound examination between 2007 and 2012 were retrospectively evaluated. TD was measured at the deepest portion of the tumor. MS was classified as “pressure,” “wedge-shaped,” or “permeated.” Prognosis was assessed by local recurrence, lymph node metastasis, and overall survival rate. We classified the patients into a good prognosis group and poor prognosis group. Relationships among TD, MS, and patient prognosis were evaluated using Spearman rank correlation. A regression formula to predict prognosis using TD and MS was derived.

Results

The correlation between TD and MS was significant (Spearman rank correlation ρ = 0.552, p < 0.01). Using a structure matrix, we identified the contribution of both predictors from an ultrasound image. The contribution of TD was 0.796, while that of MS was better at 0.906. The prognosis could be predicted using the following regression formula: \( D \, = \, - 2.801 \, + \, 0.093x \, + \, 0.872y \), where D prognosis (risk probability), x = TD (mm), and y = MS (grade). The average value for good risk probability was −0.254 (standard deviation, 0.962), while that for poor risk probability was 0.566 (standard deviation, 1.08) (p < 0.05). The cut-off value for classifying cases was −0.00169. Using the formula above, 73.1 % of patients in the poor prognosis group were correctly classified.

Conclusions

MS and TD are useful predictors of tongue cancer prognosis.

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Title: Estimation of prognosis of tongue cancer using tumor depth and margin shape obtained from ultrasonography
Authors: Sitti Fadhillah Oemar Mattalitti
Toshiyuki Kawazu
Shintaro Kawano
Tatsuya Ikari
Hiroko Wada
Kazunori Yoshiura
Publication date: 01-05-2017
Publisher: Springer Singapore
Published in: Oral Radiology / Issue 2/2017
Print ISSN: 0911-6028
Electronic ISSN: 1613-9674
DOI: https://doi.org/10.1007/s11282-016-0251-y

ACC 2024 Congress

Springer Medicine

Estimation of prognosis of tongue cancer using tumor depth and margin shape obtained from ultrasonography

Abstract

Objectives

Methods

Results

Conclusions

ACC 2024 Congress

Springer Medicine

Abstract

Objectives

Methods

Results

Conclusions

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