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Quality of Life Research

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01-02-2021 | Epilepsy

Quality of life among patients with epilepsy in Nigeria: predictors and barriers to routine clinical use of QOLIE-31

Authors: Temitope Ogundare, Timothy O. Adebowale, Obinna A. Okonkwo

Published in: Quality of Life Research | Issue 2/2021

Abstract

Purpose

To determine the factors predicting poorer quality of life (QOL) among patients with epilepsy attending an out-patient clinic in a Nigerian tertiary hospital, and reflect on the barriers to successful adoption of a structured QOL instrument into routine clinical practice.

Methods

Two-hundred and seventy patients with a diagnosis of epilepsy attending the Neuropsychiatric Hospital, Abeokuta, Nigeria were recruited. Sociodemographic and clinical information were collected using a proforma. QOLIE-31 was administered to measure QOL.

Results

The mean (SD) QOLIE-31 scores were 77.98 (13.32), with 15.2%, 74.1%, and 10.7% of the respondents classified as low, moderate, and high QOL, respectively. Factors associated with poorer QOL include seizure frequency, depression, and family history of epilepsy.

Conclusion

Quality of life is an important outcome measure for people with epilepsy and it focuses on the individual’s subjective assessment of their well-being. Although useful for clinical management of patients with epilepsy, the uniqueness of the practice settings and the limitations of clinical practice in a developing country pose challenges to successful adoption of structured QOL instrument into routine clinical practice.

Saxena, S., & Orley, J. (1997). Quality of life assessment: The World Health Organization perspective. European Psychiatry, 12, 263s–266s.CrossRef

Akinsulore, A., & Adewuya, A. (2010). Psychosocial aspects of epilepsy in Nigeria: A review. African Journal of Psychiatry. https://doi.org/10.4314/ajpsy.v13i5.63100.CrossRefPubMed

Wagner, A. K., & Vickrey, B. G. (1995). The routine use of health-related quality of life measures in the care of patients with epilepsy: Rationale and research agenda. Quality of Life Research, 4(2), 169–177.CrossRef

Sunmonu, T. A., Komolafe, M. A., Ogunrin, A. O., & Ogunniyi, A. (2009). Cognitive assessment in patients with epilepsy using the Community Screening Interview for Dementia. Epilepsy & Behavior, 14(3), 535–539.CrossRef

Baker, G. A. (2001). Assessment of quality of life in people with epilepsy: Some practical implications. Epilepsia, 42(SUPPL. 3), 66–69.CrossRef

Grudzinski, A. N., Hakim, Z., Coons, S. J., & Labiner, D. M. (1998). Use of the QOLIE-31 in routine clinical practice. Journal of Epilepsy, 11(1), 34–47.CrossRef

Awaritefe, A., Longe, A. C., & Awaritefe, M. (1985). Epilepsy and psychosis: A comparison of societal attitudes. Epilepsia, 26(1), 1–9.CrossRef

Nabukenya, A. M., Matovu, J. K. B., Wabwire-Mangen, F., Wanyenze, R. K., & Makumbi, F. (2014). Health-related quality of life in epilepsy patients receiving anti-epileptic drugs at National Referral Hospitals in Uganda: A cross-sectional study. Health and Quality of Life Outcomes, 12(1), 49. CrossRef

Ogundare, T., Adebowale, T. O., Borba, C. P. C., & Henderson, D. C. (2020). Correlates of depression and quality of life among patients with epilepsy in Nigeria. Epilepsy Research, 164, 106344. https://www.sciencedirect.com/science/article/pii/S0920121120300838.

10.

Cramer, J. A., Perrine, K., Devinsky, O., Bryant-Comstock, L., Meador, K., Hermann, B. (1998). Development and cross-cultural translations of a 31-item quality of life in epilepsy inventory. Epilepsia, 39(1), 81–88. https://www.ncbi.nlm.nih.gov/pubmed/9578017.

11.

Adebayo, P. B., Akinyemi, R. O., Ogun, S. A., & Ogunniyi, A. (2014). Seizure severity and health-related quality of life of adult Nigerian patients with epilepsy. Acta Neurologica Scandinavica, 129(2), 102–108. https://doi.org/10.1111/ane.12146.CrossRefPubMed

12.

Fawale, M. B., Owolabi, M. O., & Ogunniyi, A. (2014). Effects of seizure severity and seizure freedom on the health-related quality of life of an African population of people with epilepsy. Epilepsy & Behavior, 32, 9–14. https://www.ncbi.nlm.nih.gov/pubmed/24463302.

13.

Adebayo, P. B., Abayomi, O., & Ogun, S. A. (2014). Risk and impact of inter-ictal depression on quality of life of Nigerian Women with epilepsy of childbearing age. Journal of Behavioral Health, 3(3), 187–191. https://www.scopemed.org/?mno=160783.

14.

Saadi, A., Patenaude, B., & Mateen, F. J. (2016). Quality of life in epilepsy—31 inventory (QOLIE-31) scores: A global comparison. Epilepsy and Behavior, 65, 13–17. https://doi.org/10.1016/j.yebeh.2016.09.032

15.

Yue, L., Yu, P., Zhao, D., Wu, D., Zhu, G., Wu, X., et al. (2011). Determinants of quality of life in people with epilepsy and their gender differences. Epilepsy & Behavior, 22(4), 692–696. https://www.sciencedirect.com/science/article/pii/S1525505011004860.

16.

Kwan, P., Yu, E., Leung, H., Leon, T., & Mychaskiw, M. A. (2009). Association of subjective anxiety, depression, and sleep disturbance with quality-of-life ratings in adults with epilepsy. Epilepsia, 50, 1059–1066. CrossRef

17.

Stavem, K., Bjornes, H., & Lossius, M. I. (2000). Reliability and validity of a Norwegian Version of the Quality of Life in Epilepsy Inventory (QOLIE-89). Epilepsia, 41(1), 91–97. https://doi.wiley.com. https://doi.org/10.1111/j.1528-1157.2000.tb01511.x.

18.

Zhao, Y., Wu, H., Li, J., Dong, Y., Liang, J., Zhu, J., et al. (2011). Quality of life and related factors in adult patients with epilepsy in China. Epilepsy & Behavior, 22(2), 376–379. https://www.sciencedirect.com/science/article/pii/S1525505011004343.

19.

Leidy, N. K., Elixhauser, A., Vickrey, B., Means, E., & Willian, M. K. (1999). Seizure frequency and the health-related quality of life of adults with epilepsy. Neurology, 53(1), 162–166. https://doi.org/10.1212/wnl.53.1.162

20.

Mosaku, K. S., Fatoye, F. O., Komolafe, M., Lawal, M., & Ola, B. A. (2006). Quality of life and associated factors among adults with epilepsy in Nigeria. International Journal of Psychiatry in Medicine, 36(4), 469.CrossRef

21.

Ettinger, A. B., Good, M. B., Manjunath, R., Edward Faught, R., & Bancroft, T. (2014). The relationship of depression to antiepileptic drug adherence and quality of life in epilepsy. Epilepsy & Behavior, 36(0), 138–143. https://www.sciencedirect.com/science/article/pii/S1525505014001711.

22.

Boylan, L. S., Flint, L. A., Labovitz, D. L., Jackson, S. C., Starner, K., & Devinsky, O. (2004). Depression but not seizure frequency predicts quality of life in treatment-resistant epilepsy. Neurology, 62, 258–261.CrossRef

23.

Jacoby, A., & Baker, G. A. (2008). Quality-of-life trajectories in epilepsy: A review of the literature. Epilepsy & Behavior, 12(4), 557–571.CrossRef

24.

Wasson, J., Keller, A., Rubenstein, L., Hays, R., Nelson, E., & Johnson, D. (1992). Benefits and obstacles of health status. Assessment in ambulatory settings: The clinician’s point of view. Medical Care, 30(5), MS42–MS49.PubMed

25.

Cramer, J. A. (1994). Quality of life for people with epilepsy. Neurologic Clinics, 12(1), 1–13.CrossRef

Title: Quality of life among patients with epilepsy in Nigeria: predictors and barriers to routine clinical use of QOLIE-31
Authors: Temitope Ogundare
Timothy O. Adebowale
Obinna A. Okonkwo
Publication date: 01-02-2021
Publisher: Springer International Publishing
Keyword: Epilepsy
Published in: Quality of Life Research / Issue 2/2021
Print ISSN: 0962-9343
Electronic ISSN: 1573-2649
DOI: https://doi.org/10.1007/s11136-020-02643-x

At a glance: The STEP trials

Springer Medicine

Quality of life among patients with epilepsy in Nigeria: predictors and barriers to routine clinical use of QOLIE-31

Abstract

Purpose

Methods

Results

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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