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Quality of Life Research
Published in: Quality of Life Research 12/2017

Open Access 01-12-2017

Association between chronic conditions and health-related quality of life: differences by level of urbanization in Peru

Authors: Alvaro Taype-Rondan, Elizabeth Sarah Abbs, Maria Lazo-Porras, William Checkley, Robert H. Gilman, Liam Smeeth, J. Jaime Miranda, Antonio Bernabe-Ortiz

Published in: Quality of Life Research | Issue 12/2017

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Abstract

Purpose

To evaluate the role of urbanization as an effect modifier for the association between specific chronic conditions and number of conditions with health-related quality of life (QOL).

Methods

We analyzed cross-sectional data from the CRONICAS Cohort Study conducted in Lima (highly urbanized), Tumbes (semi-urban), as well as rural and urban sites in Puno. Exposures of interest were chronic bronchitis, depressive mood, hypertension, type 2 diabetes, and a composite variable aggregating the number of chronic conditions (the four exposures plus heart disease and stroke). QOL outcomes were assessed with EuroQol’s EQ-5D visual analogue scale (EQ-VAS). We fitted linear regressions with robust variance to evaluate the associations of interest. Study site was assessed as a potential effect modifier using the likelihood-ratio (LR) test.

Results

We evaluated data on 2433 subjects: 51.3% were female, mean age was 57.2 years. Study site was found to be an effect modifier only for the association between depressive mood and EQ-VAS score (LR test p < 0.001). Compared to those without depressive mood, participants with depressive mood scored −13.7 points on the EQ-VAS in Lima, −7.9 in urban Puno, −11.0 in semi-urban Tumbes, and −2.7 in rural Puno. Study site was not found to be an effect modifier for the association between the number of chronic conditions and EQ-VAS (LR test p = 0.64).

Conclusion

The impact of depressive mood on EQ-VAS was larger in urban than in rural sites, while site was not an effect modifier for the remaining associations.
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Metadata
Title
Association between chronic conditions and health-related quality of life: differences by level of urbanization in Peru
Authors
Alvaro Taype-Rondan
Elizabeth Sarah Abbs
Maria Lazo-Porras
William Checkley
Robert H. Gilman
Liam Smeeth
J. Jaime Miranda
Antonio Bernabe-Ortiz
Publication date
01-12-2017
Publisher
Springer International Publishing
Published in
Quality of Life Research / Issue 12/2017
Print ISSN: 0962-9343
Electronic ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-017-1649-7

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